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Xenobiotica
the fate of foreign compounds in biological systems
Volume 2, 1972 - Issue 1
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Research Article

Retention, Metabolism and Elimination of 17α-Ethynyl-Estradiol-3-Methyl Ether (Mestranol)

H. M. Bolt Institute of Toxicology, University of Töbingen, Germany
&
H. Remmer Institute of Toxicology, University of Töbingen, Germany
Pages 77-88 | Received 21 Oct 1971, Published online: 22 Sep 2008

Citations (15)

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Read on this site (3)

J. L. Maggs, P. S. Grabowski & B. K. Park. (1983) The enterohepatic circulation of the metabolites of 17α-ethynyl[3H]estradiol in the rat. Xenobiotica 13:10, pages 619-626.
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Hermann M. Bolt, Hermann Kappus & Herbert Remmer. (1973) Studies on the Metabolism of Ethynylestradiol in vitro and in vivo: The Significance of 2-Hydroxylation and the Formation of Polar Products. Xenobiotica 3:12, pages 773-785.
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H. M. Bolt & H. Remmer. (1972) The Accumulation of Mestranol and Ethynyloestradiol Metabolites in the Organism. Xenobiotica 2:5, pages 489-498.
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Articles from other publishers (12)

Michel Oettel & Ekkehard SchillingerW. Kuhnz, H. Blode & H. Zimmermann. 1999. Estrogens and Antiestrogens II. Estrogens and Antiestrogens II 261 322 .
Humeida A. El-Obeid & Abdullah A. Al-Badr. 1982. 375 406 .
Nello J. Spiteri, Robert F. Drewett & Una Padel. (1980) Behavioral effects of ethynyl estrogens in the female rat. Physiology & Behavior 25:3, pages 409-415.
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Betty L. Warren & Gail D. Bellward. (2016) Benign Liver Tumors and Oral Contraceptive Therapy. Drug Intelligence & Clinical Pharmacy 13:11, pages 680-689.
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H.M. Bolt. (1979) Metabolism of estrogens—natural and synthetic. Pharmacology & Therapeutics 4:1, pages 155-181.
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David Brewster, Robin S. Jones & Andrew M. Symons. (1977) Effects of neomycin on the biliary excretion and enterohepatic circulation of mestranol and 17β-oestradiol. Biochemical Pharmacology 26:10, pages 943-946.
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Edward D. Helton & Joseph W. Goldzieher. (1977) The pharmacokinetics of ethynyl estrogens. A review. Contraception 15:3, pages 255-284.
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Ira Weinstein, Richard Belitsky, Susan Seedman, Melvin J. Fregly & Terry N. Thrasher. (1975) Effect of long-term therapy with an oral contraceptive on some aspects of hepatic lipid metabolism in vitro. Biochemical Pharmacology 24:17, pages 1583-1588.
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C. Longcope & K.I.H. Williams. (1975) The metabolism of synthetic estrogens in non-users and users of oral contraceptives. Steroids 25:1, pages 121-133.
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H. M. Bolt & W. H. Bolt. (1974) Pharmacokinetics of mestranol in man in relation to its oestrogenic activity. European Journal of Clinical Pharmacology 7:4, pages 295-305.
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H. Kappus, H.M. Bolt & H. Remmer. (1973) Irreversible protein binding of metabolites of ethynylestradiol in vivo and in vitro. Steroids 22:2, pages 203-225.
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H. Kappus, H.M. Bolt & H. Remmer. (1973) Affinity of ethynyl-estradiol and mestranol for the uterine estrogen receptor and for the microsomal mixed function oxidase of the liver. Journal of Steroid Biochemistry 4:2, pages 121-128.
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