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Xenobiotica
the fate of foreign compounds in biological systems
Volume 2, 1972 - Issue 2
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Research Article

Metabolism of Oxisuran, an Immunosuppressant, by the Rat

Frederick J. Di Carlo Department of Drug Metabolism, Warner-Lambert Research Institute, Morris Plains, New Jersey, 07950, USA
,
Malcolm C. Crew Department of Drug Metabolism, Warner-Lambert Research Institute, Morris Plains, New Jersey, 07950, USA
,
Lloyd J. Haynes Department of Drug Metabolism, Warner-Lambert Research Institute, Morris Plains, New Jersey, 07950, USA
&
Rosemarie L. Gala Department of Drug Metabolism, Warner-Lambert Research Institute, Morris Plains, New Jersey, 07950, USA
Pages 159-168 | Received 15 Nov 1971, Published online: 22 Sep 2008

Citations (10)

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Read on this site (3)

Frederick J. Di Carlo. (1979) Interspecies Comparisons of Oxisuran Metabolism and Pharmacokinetics. Drug Metabolism Reviews 10:2, pages 225-237.
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Franz-Josef Leinweber, R. Clive Greenough & Frederick J. Di Carlo. (1976) A New Oxisuran Metabolite. Xenobiotica 6:10, pages 617-624.
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Malcolm C. Crew, Myriam D. Melgar, Lloyd J. Haynes, Rosemarie L. Gala & Frederick J. Di Carlo. (1972) Disposition and Biotransformation of 14C-Oxisuran in the Dog. Xenobiotica 2:5, pages 431-440.
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Articles from other publishers (7)

H. El Ouazzani, N. Khiar, I. Fernández & F. Alcudia. (1997) General Method for Asymmetric Synthesis of α-Methylsulfinyl Ketones:  Application to the Synthesis of Optically Pure Oxisuran and Bioisosteres. The Journal of Organic Chemistry 62:2, pages 287-291.
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F. Alcudia, I. Fernández, J.M. Llera, M. Trujillo & F. Zorrilla. (1989) Studies on conformation and configuration of β-hydroxysulphoxides. Journal of Molecular Structure: THEOCHEM 186, pages 211-238.
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J.L.Garcia Ruano, C. Pedregal & J.H. Rodriguez. (1987) Synthesis and conformational analysis of some oxisuran metabolites and their o-methylderivatives. Tetrahedron 43:19, pages 4407-4416.
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Daniel B. Prelusky, Ronald T. Coutts & Franco M. Pasutto. (1982) Stereospecific Metabolic Reduction of Ketones. Journal of Pharmaceutical Sciences 71:12, pages 1390-1393.
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Garvin S. BixlerJr.Jr. & T.Juhani Linna. (1982) Oxisuran: Influence on allograft rejection and graft versus host reactivity in chickens and mice. Immunopharmacology 4:1, pages 79-85.
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G. Briziarelli, D. Abrutyn, J.A. Tornaben & E. Schwartz. (1976) Safety evaluation studies on oxisuran, a differential inhibitor of cell-mediated hypersensitivity. Toxicology and Applied Pharmacology 36:1, pages 49-64.
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F. J. Di Carlo, P. J. Jacques, N. R. Di Luzio, J. Hobeke, G. Lázár, R. L. Gross, P. M. Newberne, E. G. Bliznakov, R. Gallily, K. Flemming, M. Timar, S. S. Lefkowitz, G. De Francisci, M. De Giacomo, E. Scrascia, S. I. Magalini & J. P. Gusdon. 1976. The Reticuloendothelial System in Health and Disease. The Reticuloendothelial System in Health and Disease 411 471 .

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