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Xenobiotica
the fate of foreign compounds in biological systems
Volume 2, 1972 - Issue 3
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Research Article

The Metabolism of Some Aromatic Aldehydes and Alcohols by the Rat Intestinal Microflora

Pages 227-236 | Received 14 Jan 1972, Published online: 22 Sep 2008

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D. Kirkpatrick, D. R. Hawkins, L. F. Chasseaud, C. M. Finn, B. Conway, M. R. Al-ani & A. F. Al-sayyab. (1983) The metabolism of salicylidene benzylamine, a pro-drug for salicylate, in rats and dogs. Xenobiotica 13:1, pages 53-64.
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Linda P. Strand & Ronald R. Scheline. (1975) The Metabolism of Vanillin and Isovanillin in the Rat. Xenobiotica 5:1, pages 49-63.
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Ralph Gingell. (1973) Substrate Non-specificity of Streptococcus faecalis Azoreductase. Xenobiotica 3:3, pages 165-169.
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Hyun Wook Huh, Hee-Yong Song, Young-Guk Na, Minki Kim, Mingu Han, Thi Mai Anh Pham, Hyeonmin Lee, Jungkyu Suh, Seok-Jong Lee, Hong-Ki Lee & Cheong-Weon Cho. (2020) Bioanalytical Method Development and Validation of Veratraldehyde and Its Metabolite Veratric Acid in Rat Plasma: An Application for a Pharmacokinetic Study. Molecules 25:12, pages 2800.
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A.M. Api, D. Belsito, S. Biserta, D. Botelho, M. Bruze, G.A. BurtonJr.Jr., J. Buschmann, M.A. Cancellieri, M.L. Dagli, M. Date, W. Dekant, C. Deodhar, A.D. Fryer, S. Gadhia, L. Jones, K. Joshi, A. Lapczynski, M. Lavelle, D.C. Liebler, M. Na, D. O'Brien, A. Patel, T.M. Penning, G. Ritacco, F. Rodriguez-Ropero, J. Romine, N. Sadekar, D. Salvito, T.W. Schultz, F. Siddiqi, I.G. Sipes, G. Sullivan, Y. Thakkar, Y. Tokura & S. Tsang. (2019) RIFM fragrance ingredient safety assessment, anisyl alcohol, CAS registry number 105-13-5. Food and Chemical Toxicology 134, pages 110702.
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. (2012) Scientific Opinion on Flavouring Group Evaluation 20, Revision 4 (FGE.20Rev4): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30. EFSA Journal 10:12.
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D. Belsito, D. Bickers, M. Bruze, P. Calow, M.L. Dagli, A.D. Fryer, H. Greim, Y. Miyachi, J.H. Saurat & I.G. Sipes. (2012) A toxicological and dermatological assessment of aryl alkyl alcohol simple acid ester derivatives when used as fragrance ingredients. Food and Chemical Toxicology 50, pages S269-S313.
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J. Scognamiglio, L. Jones, C.S. Letizia & A.M. Api. (2012) Fragrance material review on anisyl alcohol. Food and Chemical Toxicology 50, pages S134-S139.
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. (2012) Scientific Opinion on the safety and efficacy of benzyl alcohols, aldehydes, acids, esters and acetals (chemical group 23) when used as flavourings for all animal species. EFSA Journal 10:7.
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. (2011) Scientific Opinion on Flavouring Group Evaluation 20, Revision 3(FGE.20Rev3): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30. EFSA Journal 9:7.
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. (2010) Scientific Opinion on Flavouring Group Evaluation 20, Revision 2 (FGE.20Rev2): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30. EFSA Journal 8:7, pages 1405.
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. (2009) Flavouring Group Evaluation 20, Revision 1 (FGE.20Rev1): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters from chemical group 23. EFSA Journal 7:2, pages 976.
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. (2006) Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to Flavouring Group Evaluation 20 (FGE.20): Benzyl alcohols, benzaldehydes, a related acetal,. EFSA Journal 4:1, pages 296.
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T.B. Adams, S.M. Cohen, J. Doull, V.J. Feron, J.I. Goodman, L.J. Marnett, I.C. Munro, P.S. Portoghese, R.L. Smith, W.J. Waddell & B.M. Wagner. (2005) The FEMA GRAS assessment of hydroxy- and alkoxy-substituted benzyl derivatives used as flavor ingredients. Food and Chemical Toxicology 43:8, pages 1241-1271.
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Kenneth F. Ilett, Lisa B.G. Tee, Philip T. Reeves & Rodney F. Minchin. (1990) Mebolism of drugs and other xenobiotics in the gut lumen and wall. Pharmacology & Therapeutics 46:1, pages 67-93.
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Lawrence Fishbein. (2016) An Overview of Some Metabolic and Modulating Factors in Toxicity and Chemical Carcinogenesis. Journal of the American College of Toxicology 2:1, pages 63-89.
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David M. Conning & A. B. G. LansdownI. R. Rowland & R. Walker. 1983. Toxic Hazards in Food. Toxic Hazards in Food 183 274 .
A.G. Renwick. 1982. Presystemic Drug Elimination. Presystemic Drug Elimination 3 28 .
. 1979. Monographs on Fragrance Raw Materials. Monographs on Fragrance Raw Materials 719 724 .
D.L.J. Opdyke. (1977) Monographs on fragrance raw materials. Food and Cosmetics Toxicology 15:6, pages 633-638.
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R. Walker. (2007) The influence of gut micro-organisms on the metabolism of drugs and food additives. Proceedings of the Nutrition Society 32:2, pages 73-78.
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