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Xenobiotica
the fate of foreign compounds in biological systems
Volume 3, 1973 - Issue 1
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Research Article

Glucuronide Synthesis in the Rat and Guinea Pig Lung

Pages 13-22 | Received 25 Aug 1972, Published online: 14 Oct 2008

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G. M. Pacifici, M. Franchi, C. Bencini, F. Repetti, N. Di Lascio & G. B. Muraro. (1988) Tissue distribution of drug-metabolizing enzymes in humans. Xenobiotica 18:7, pages 849-856.
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I. C. Shaw, A. M. Hackett & L. A. Griffiths. (1982) Metabolism and excretion of the liver-protective agent (+)-catechin in experimental hepatitis. Xenobiotica 12:7, pages 405-416.
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Robin H. Briant, Elaine W. Blackwell, Faith M. Williams, Donald S. Davies & Colin T. Dollery. (1973) The Metabolism of Sympathomimetic Bronchodilator Drugs by the Isolated Perfused Dog Lung. Xenobiotica 3:12, pages 787-799.
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Articles from other publishers (43)

Souradipta Ganguly, Taposh Kumar G.Sudarshan Mantha & Koustubh Panda. (2016) Simultaneous Determination of Black Tea-Derived Catechins and Theaflavins in Tissues of Tea Consuming Animals Using Ultra-Performance Liquid-Chromatography Tandem Mass Spectrometry. PLOS ONE 11:10, pages e0163498.
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E. Hietanen, J. Marniemi, K. Liippo, A. Seppänen, J. Hartiala & O. Viinamäki. (2008) Role of pulmonary diseases and physical condition in the regulation of vasoactive hormones. Clinical Physiology 8:6, pages 581-590.
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Hiroshi Yokota, Hisahiko Hashimoto, Michiyo Motoya & Akira Yuasa. (1988) Enhancement of UDP-glucuronyltransferase, UDP-glucose dehydrogenase, and glutathione S-transferase activities in rat liver by dietary administration of eugenol. Biochemical Pharmacology 37:5, pages 799-802.
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Michael Mollière, Heidi Foth, Regine Kahl & Georg F. Kahl. (1987) Metabolism of benzo[α] pyrene in the combined rat liver —lung perfusion system. Toxicology 45:2, pages 143-154.
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Katarina Victorin, Leif Busk & Ulf G. Ahlborg. (1987) Retinol (vitamin A) inhibits the mutagenicity of o-aminoazotoluene activated by liver microsomes from several species in the Ames test. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 179:1, pages 41-48.
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Michael Molli�re, Heidi Foth, Regine Kahl & Georg F. Kahl. (1987) Comparison of benzo(a)pyrene metabolism in isolated perfused rat lung and liver. Archives of Toxicology 60:4, pages 270-277.
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Daniel M. Bagley & Johnnie R. Hayes. (1985) Neonatal phenobarbital imprinting of hepatic microsomal enzymes in adult rats: Modulation by neonatal testosterone presence. Toxicology and Applied Pharmacology 79:2, pages 227-235.
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Daniel M. Bagley & Johnnie R. Hayes. (1985) Xenobiotic imprinting of the hepatic monooxygenase system. Biochemical Pharmacology 34:7, pages 1007-1014.
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Tuula Thunberg, Ulf G. Ahlborg & Bo Wahlstr�m. (1984) Comparison between the effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin and six other compounds on the vitamin A storage, the UDP-glucuronosyltransferase and the aryl hydrocarbon hydroxylase activity in the rat liver. Archives of Toxicology 55:1, pages 16-19.
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D.M. Bagley & J.R. Hayes. (1983) Neonatal phenobarbital administration results in increased cytochrome P450-dependent monooxygenase activity in adult male and female rats. Biochemical and Biophysical Research Communications 114:3, pages 1132-1137.
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Tuula Thunberg & Helen H�kansson. (1983) Vitamin A (retinol) status in the Gunn rat. Archives of Toxicology 53:3, pages 225-233.
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Jeffrey Baron & Thomas T. Kawabata. 1983. Biological Basis of Detoxication. Biological Basis of Detoxication 105 135 .
Gary E.R. Hook. 1982. Presystemic Drug Elimination. Presystemic Drug Elimination 117 146 .
S.I. Hogg, C.G. Curtis, D.G. Upshall & G.M. Powell. (1981) Conjugation of phenol by rat lung. Biochemical Pharmacology 30:12, pages 1551-1555.
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Tuula Thunberg, Ulf G. Ahlborg, Helen H�kansson, Cilla Krantz & Mats Monier. (1980) Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the hepatic storage of retinol in rats with different dietary supplies of vitamin A (retinol). Archives of Toxicology 45:4, pages 273-285.
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CHARLES B. KASPER & DONABY HENTON. 1980. Enzymatic Basis of Detoxication. Enzymatic Basis of Detoxication 3 36 .
V.Paul AddonizioJr.Jr. & Alden H. Harken. (1980) The surgical implications of nonrespiratory lung function. Journal of Surgical Research 28:1, pages 86-95.
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G. D. Paulson. 1980. Residue Reviews. Residue Reviews 31 72 .
Niklas Simberg & Pekka Uotila. (2006) Stimulatory effect of cigarette smoke on the metabolism and covalent binding of benzo( a )pyrene in the trachea of the rat . International Journal of Cancer 22:1, pages 28-31.
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A. Norling. (1978) Buffer effects on the xenobiotic hydroxylation and glucuronidation catalyzed by native and pretreated rat liver microsomes. Pharmacological Research Communications 10:6, pages 511-527.
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Åke Ryrfeldt & Elisabeth Nilsson. (1978) Uptake and biotransformation of ibuterol and terbutaline in isolated perfused rat and guinea pig lungs. Biochemical Pharmacology 27:3, pages 301-305.
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Robert M. Hollingworth. 2011. Comprehensive Physiology. Comprehensive Physiology 455 468 .
Kirsi Vähäkangas, Kaisu Nevasaari, Olavi Pelkonen & Niilo T. Kärki. (2009) The Metabolism of Benzo(a)pyrene in Isolated Perfused Lungs from Variously‐treated Rats. Acta Pharmacologica et Toxicologica 41:2, pages 129-140.
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J P Gorski & C B Kasper. (1977) Purification and properties of microsomal UDP-glucuronosyltransferase from rat liver.. Journal of Biological Chemistry 252:4, pages 1336-1343.
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Harri Vainio, Jukka Marniemi, Max Parkki & Reijo Luoma. 1977. Biological Reactive Intermediates. Biological Reactive Intermediates 251 262 .
A. Aitio & H. Vainio. (2009) UDPGlucuronosyltransferase and Mixed Function Oxidase Activity in Microsomes Prepared by Differential Centrifugation and Calcium Aggregation. Acta Pharmacologica et Toxicologica 39:5, pages 555-561.
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Pekka Uotila & Jukka Marniemi. (1976) Variable effects of cigarette smoking on aryl hydrocarbon hydroxylase, epoxide hydratase and UDP-glucuronosyltransferase activities in rat lung, kidney and small intestinal mucosa. Biochemical Pharmacology 25:20, pages 2323-2328.
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Antero Aitio, Jaakko Hartiala & Pekka Uotila. (1976) Glucuronide synthesis in the isolated perfused rat lung. Biochemical Pharmacology 25:16, pages 1919-1920.
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Antero Aitio. (1976) Glucuronide conjugation in the lung. Agents and Actions 6:4, pages 531-533.
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J. Hartiala. (1976) Steroid metabolism in adult lung. Agents and Actions 6:4, pages 522-526.
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Gary E.R. Hook & John R. Bend. (1976) Pulmonary metabolism of xenobiotics. Life Sciences 18:3, pages 279-290.
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Jukka Marniemi, Antero Aitio & Harri Vainio. (2009) Ethanol Induced Alteration of Microsomal Membrane Bound Enzymes of Rat Liver in Vitro . Acta Pharmacologica et Toxicologica 37:3, pages 222-232.
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Edward G. Mimnaugh, Charles L. Litterst & Theodore E. Gram. (1975) Effects of activators in vitro on rabbit lung and liver microsomal UDP-glucuronyl-transferase activity. Biochemical Pharmacology 24:17, pages 1633-1635.
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Harri Vainio & Antero Aitio. (2009) Influence of Hematin, Carbon Tetrachloride and SKF 525‐A Administration on the Enhancement of Microsomal Monooxygenase and UDPglucuronosyltransferase by 3,4‐Benzpyrene in Rat Liver. Acta Pharmacologica et Toxicologica 37:1, pages 23-32.
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J.M. Ziegler, B.P. Lisboa, A.M. Batt & G. Siest. (1975) Determination of UDP-glucuronyltransferase using UDP-[14C]glucuronic acid. Biochemical Pharmacology 24:13-14, pages 1291-1292.
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Terence E. Nicholas & Patricia A. Kim. (1975) The metabolism of 3H-cortisone and 3H-cortisol by the isolated perfused rat and guinea pig lungs. Steroids 25:3, pages 387-402.
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H. Vainio & O. Hänninen. (2009) A Comparative Study on Drug Hydroxylation and Glucuronidation in Liver Microsomes of Phenobarbital and 3‐Methylcholanthrene Treated Rats. Acta Pharmacologica et Toxicologica 35:1, pages 65-75.
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Antero Aitio. (1974) Effect of various membrane perturbating agents on the UDP-glucuronosyltransferase activity in different rat tissues. International Journal of Biochemistry 5:7-8, pages 617-621.
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Antero Aitio. (1974) Effect of chrysene and carbon tetrachloride administration on rat hepatic microsomal monooxygenase and UDPglucuronosyltransferase activity. FEBS Letters 42:1, pages 46-49.
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Antero Aitio. (1974) UDF glucuronyltransferase activity in various rat tissues. International Journal of Biochemistry 5:3, pages 325-330.
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Harri Vainio & Antero Aitio. (2009) Enhancement of Microsomal Drug Hydroxylation and Glucuronidation in Rat Liver by Phenobarbital and 3‐Methylcholanthrene in Combination. Acta Pharmacologica et Toxicologica 34:2, pages 130-140.
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A. Aitio. (1973) Induction of UDP glucuronyltransferase in the liver and extrahepatic organs of the rat. Life Sciences 13:12, pages 1705-1713.
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