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Xenobiotica
the fate of foreign compounds in biological systems
Volume 3, 1973 - Issue 6
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Research Article

The Stimulation of Lipid Peroxidation Produced by Dimethylnitrosamine in Rat Liver Microsomes in vitro: The Effects of Promethazine and Inhibitors of Drug Metabolism, and a Comparison with Previous Studies using Carbon Tetrachloride

P. J. Jose Department of Biochemistry, Brunel University, Kingston Lane, Uxbridge, Middlesex, UB8 3PH, England
&
T. F. Slater Department of Biochemistry, Brunel University, Kingston Lane, Uxbridge, Middlesex, UB8 3PH, England
Pages 357-366 | Received 04 Nov 1972, Published online: 14 Oct 2008

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Read on this site (2)

M. Ahotupa, J. C. Béréziat, V. Bussacchini Griot, A. M. Camus & H. Bartsch. (1987) Lipid Peroxidation Induced ByN-Nitrosodimethylamine (Ndma) In Rats In Vivo and in Isolated Hepatocytes. Free Radical Research Communications 3:1-5, pages 285-291.
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B. G. Lake, M. A. Collins, Rosalyn A. Harris, J. C. Phillips, R. C. Cottrell & S. D. Gangolli. (1982) Studies on the metabolism of dimethylnitrosamine in vitro by rat-liver preparations.: I. Comparison with mixed-function oxidase enzymes. Xenobiotica 12:7, pages 435-445.
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Articles from other publishers (10)

Reham Z. Hamza, Hayat A.A. Ismail & Nahla S. El-Shenawy. (2017) Oxidative stress, histopathological and electron microscopic alterations induced by dimethylnitrosamine in renal male mice and the protective effect of α-lipoic acid. Journal of Basic and Clinical Physiology and Pharmacology 28:2, pages 149-158.
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Helmut Bartsch, Eino Hietanen & Christian Malaveille. (1989) Carcinogenic nitrosamines: Free radical aspects of their action. Free Radical Biology and Medicine 7:6, pages 637-644.
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Janet C. Ludwig & Milos Chvapil. 1982. Inflammatory Diseases and Copper. Inflammatory Diseases and Copper 565 580 .
Carl E. Aronson & Elaine R.S. Hanno. (1979) Effects of promethazine on the isolated perfused rat heart. General Pharmacology: The Vascular System 10:5, pages 389-395.
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Robert A. Floyd, Lailing M. Soong, Melissa A. Stuart & Darryel L. Reigh. (1978) SPIN TRAPPING OF FREE RADICALS PRODUCED FROM NITROSOAMINE CARCINOGENS. Photochemistry and Photobiology 28:4-5, pages 857-862.
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A.N. Saprin, J. Ramseyer, J. McConn & L.H. Piette. (1977) Electron spin resonance and optical spectra of the complexes of dialkylnitrosoamines with cytochrome P-450. Biochemical and Biophysical Research Communications 77:2, pages 789-796.
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H. Kappus, H. Kieczka, M. Scheulen & H. Remmer. (1977) Molecular aspects of catechol and pyrogallol inhibition of liver microsomal lipid peroxidation stimulated by ferrous ion-ADP-complexes or by carbon tetrachloride. Naunyn-Schmiedeberg's Archives of Pharmacology 300:2, pages 179-187.
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S.S. Thorgeirsson, J.R. Mitchell, H.A. SaSame & W.Z. Potter. (1976) Biochemical changes after hepatic injury by allyl alcohol and N-hydroxy-2-acetylaminoflourene. Chemico-Biological Interactions 15:2, pages 139-147.
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Brian G. Lake, John C. Phillips, Christine E. Heading & Sharat D. Gangolli. (1976) Studies on the in vitro metabolism of dimethylnitrosamine by rat liver. Toxicology 5:3, pages 297-309.
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N. D'Acosta, J.A. Castro, C.R. de Castro, M.I. Díaz Gómez, E.C. de Ferreyra & O.M. de Fenos. (1975) Mechanismofdimethylnitrosamine and carbon tetrachloride-induced liver necrosis: Similarities and differences. Toxicology and Applied Pharmacology 32:3, pages 474-481.
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