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Xenobiotica
the fate of foreign compounds in biological systems
Volume 3, 1973 - Issue 6
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Research Article

The Metabolism of Benomyl Fungicide in Mammals

P. G. C. Douch Wallaceville Animal Research Centre, Ministry of Agriculture and Fisheries, Upper HuttNew Zealand
Pages 367-380 | Received 09 Dec 1972, Published online: 14 Oct 2008

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L. Somerville. (1986) The metabolism of fungicides. Xenobiotica 16:10-11, pages 1017-1030.
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J. Krechniak & B. Kłosowska. (1986) The fate of 14C-carbendazim in rat. Xenobiotica 16:9, pages 809-815.
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P. G. C. Douch & L. L. Buchanan. (1979) The metabolism of nitrophenolic and 5-arylazorhodanine anthelmintics by Ascaris suum, Moniezia expansa and by mouse- and sheep-liver enzymes. Xenobiotica 9:8, pages 467-473.
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P. G. C. Douch & S. S. B. Blair. (1975) The Metabolism of Foreign Compounds in the Cestode, Moniezia expansa, and the Nematode, Ascaris lumbricoides var suum. Xenobiotica 5:5, pages 279-292.
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P. G. C. Dough. (1974) The Metabolism of some Thioureidobenzene Fungicides in Mice and Sheep. Xenobiotica 4:8, pages 457-475.
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Articles from other publishers (27)

Yanran Huang, Japhet Cheuk-Fung Law & Kelvin Sze-Yin Leung. (2023) The quest for metabolic biomarkers of agrochemicals exposure via in vitro studies and suspect screening. Science of The Total Environment 861, pages 160701.
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JAQUELINE N. DA SILVA, NAYARA R. MONTEIRO, PATRICIA A. ANTUNES & ANA PAULA A. FAVARETO. (2020) Maternal and developmental toxicity after exposure to formulation of chlorothalonil and thiophanate-methyl during organogenesis in rats. Anais da Academia Brasileira de Ciências 92:4.
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Amina Farag, Hala Ebrahim, Reda ElMazoudy & Ezzat Kadous. (2011) Developmental toxicity of fungicide carbendazim in female mice. Birth Defects Research Part B: Developmental and Reproductive Toxicology 92:2, pages 122-130.
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Elvira González de Mejía, Marco Vinicio Ramírez-Mares & Muraleedharan G. Nair. (2002) Topoisomerase I and II Enzyme Inhibitory Aqueous Extract of Ardisia compressa and Ardisin Protect against Benomyl Oxidation of Hepatocytes . Journal of Agricultural and Food Chemistry 50:26, pages 7714-7719.
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Ronald L. Mull & Leon W. Hershberger. 2001. Handbook of Pesticide Toxicology. Handbook of Pesticide Toxicology 1673 1699 .
Sonia Radice, Laura Marabini, Marco Gervasoni, Michela Ferraris & Enzo Chiesara. (1997) Carbendazim and n-butylisocyanate: metabolites responsible for benomyl double action on cytochrome P450 in HepG2 cells. Toxicology 123:1-2, pages 135-142.
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Sonia Radice, Laura Marabini, Barbara Cipelletti & Enzo Chiesara. (2020) Effects of Benomyl on Cytochrome P450 Monooxygenase Systems in the Hep G2 Cell Line. Alternatives to Laboratory Animals 24:4, pages 589-595.
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Awni M. Sarrif, Gail T. Arce, David F. Krahn, Rita M. O'Neil & Vincent L. Reynolds. (1994) Evaluation of carbendazim for gene mutations in the Salmonella/Ames plate-incorporation assay: the role of aminophenazine impurities. Mutation Research/Genetic Toxicology 321:1-2, pages 43-56.
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R. von Burg. (2006) Benomyl. Journal of Applied Toxicology 13:5, pages 377-381.
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L.H. Leenheers, R. Engel, W.E.T. Spruit, W.J.A. Meuling & M.J.M. Jongen. (1993) Determination of methyl 5-hydroxy-2-benzimidazole carbamate in urine by high-performance liquid chromatography with electrochemical detection. Journal of Chromatography B: Biomedical Sciences and Applications 613:1, pages 89-94.
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Ramesh R. Dalvi. (1992) Effect of the fungicide benomyl on xenobiotic metabolism in rats. Toxicology 71:1-2, pages 63-68.
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I. Ralph Edwards, Donald G. Ferry & Wayne A. Temple. 1991. Classes of Pesticides. Classes of Pesticides 1409 1470 .
Björn Hellman & Daneil Laryea. (1990) Inhibitory effects of benomyl and carbendazim on the [3H]thymidine incorporation in various organs of the mouse — Evidence for a more pronounced action of benomyl. Toxicology 61:2, pages 161-169.
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B. Hellman & D. Laryea. (1990) Inhibitory action of benzimidazole fungicides on the in vivo incorporation of [3H]thymidine in various organs of the mouse. Food and Chemical Toxicology 28:10, pages 701-706.
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O. Caputo, G. Grosa, M. Ceruti, F. Viola & F. Rocco. (1989) In vivo metabolism of the anti-inflammatory agent 2-(5-ethylpyridin-2-yl)benzimidazole. European Journal of Drug Metabolism and Pharmacokinetics 14:4, pages 263-268.
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Donald U. Palawski & Charles O. Knowles. (2009) Toxicological studies of benomyl and carbendazim in rainbow trout, channel catfish and bluegills. Environmental Toxicology and Chemistry 5:12, pages 1039-1046.
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Jasenka V. Zbozinek. 1984. Residue Reviews. Residue Reviews 113 155 .
Calvin C. Willhite. (2006) Benomyl. Journal of Applied Toxicology 3:5, pages 261-264.
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R. J. Allan & T. R. Watson. (1982) Identification of biliary metabolites of Mebendazole in the rat. European Journal of Drug Metabolism and Pharmacokinetics 7:2, pages 131-136.
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. 1982. Metabolic Maps of Pesticides. Metabolic Maps of Pesticides 212 219 .
Hugh D. Sisler. 1982. Biodegradation of Pesticides. Biodegradation of Pesticides 133 155 .
P.W. Rankin, J.G. Surak & N.P. Thompson. (1977) Effect of benomyl and benomyl hydrolysis products on Tetrahymena pyriformis. Food and Cosmetics Toxicology 15:3, pages 187-193.
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R.C. Couch & H.W. Dorough. 1977. Fate of Pesticides in Large Animals. Fate of Pesticides in Large Animals 127 157 .
Austin Stringer & Michael A. Wright. (2006) The toxicity of benomyl and some related 2‐substituted benzimidazoles to the earthworm Lumbricus terrestris . Pesticide Science 7:5, pages 459-464.
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David A. M. Watkins. (2006) Benzimidazole pesticides: Analysis and transformations. Pesticide Science 7:2, pages 184-192.
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W. E. G. Meuldermans, R. M. A. Hurkmans, W. F. J. Lauwers & J. J. P. Heykants. (1976) Thein vitro metabolism of mebendazole by pig, rat and dog liver fractions. European Journal of Drug Metabolism and Pharmacokinetics 1:1, pages 35-40.
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J.P. Seiler. (1975) Toxicology and genetic effects of benzimidazole compounds. Mutation Research/Reviews in Genetic Toxicology 32:2, pages 151-167.
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