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Xenobiotica
the fate of foreign compounds in biological systems
Volume 3, 1973 - Issue 8
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Research Article

Oxidation of Polycyclic N -Arylacetamides to Glycol-amides and Hydroxamic Acids in Rabbits

Wolfgang Fries Pharmakologisches Institut der Universitat München, Munich, FRG
,
Manfred Kiese Pharmakologisches Institut der Universitat München, Munich, FRG
&
Werner Lenk Pharmakologisches Institut der Universitat München, Munich, FRG
Pages 525-540 | Received 08 Feb 1973, Published online: 14 Oct 2008

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W. Lenk & R. Rosenbauer-Thilmann. (1993) Metabolism of 2-acetylaminofluorene. I. Metabolism in vitro, of 2-acetylaminofluorene and 2-acetylaminofluoren-9-one by hepatic enzymes. Xenobiotica 23:3, pages 241-257.
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W. Lenk & H. Sterzl. (1986) N-Hydroxy-N-arylacetamides. II: Molecular aspects of ferrihaemoglobin formation by N-hydroxy-N-arylacetamides and arylhydroxylamines in the rat. Xenobiotica 16:8, pages 703-716.
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J. W. Gorrod & D. Manson. (1986) The metabolism of aromatic amines. Xenobiotica 16:10-11, pages 933-955.
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T. Fischbach & W. Lenk. (1985) Additional routes in the metabolism of phenacetin. Xenobiotica 15:2, pages 149-164.
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Peter Hlavica & John W. Gorrod. (1982) Biological Oxidation of Nitrogen in Organic Compounds and Disposition of N-Oxidized Product. Critical Reviews in Biochemistry 12:1, pages 39-101.
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G. Huizing & A. H. Beckett. (1980) Metabolism of clebopride in vitro Identification of N-oxidized products. Xenobiotica 10:7-8, pages 593-602.
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W. Lenk & U. Scharmer. (1980) Reaction of microsomal and cytosolic enzymes with N-arylacetohydroxamic acids. Xenobiotica 10:7-8, pages 573-591.
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N. M. Woolhouse, B. Kaye, A. M. Monro & D. V. Parke. (1973) The Metabolism of 5,7-Dinitroindazole in the Mouse and the Rat. Xenobiotica 3:8, pages 511-524.
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Articles from other publishers (8)

S. D. Jatoe & J. W. Gorrod. (1987) The in vitro/in vivo comparative metabolism of 4-aminobiphenyl using isolated hepatocytes. Archives of Toxicology 60:1-3, pages 65-68.
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Tilman Fischbach, Hildegard Hertle, Manfred Kiese, Werner Lenk, Heidrun Sterzl & Peter Meister. (1984) N-Hydroxy-N-arylacetamides. Archives of Toxicology 56:2, pages 96-105.
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Noel W. Davies, Werner Lenk & Stuart McLean. (2005) Mass spectra of some N ‐arylacetylhydroxamic acids, acetamidophenols and their methyl dervatives . Organic Mass Spectrometry 17:12, pages 649-651.
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Werner Lenk. (1979) Mixed function oxygenation of the lower fatty acyl residues—I. Hydroxylation of the acetic, propionic, butyric, and valeric residues by rabbit liver microsomes. Biochemical Pharmacology 28:14, pages 2149-2159.
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Michael D. Corbett, Daniel G. Baden & Bernadette R. Chipko. (1979) The nonmicrosomal production of N-(4-chlorophenyl)-glycolhydroxamic acid from 4-chloronitrosobenzene by rat liver homogenates. Bioorganic Chemistry 8:2, pages 227-235.
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Lance R. Pohl & Gopal Krishna. (1978) Study of the mechanism of metabolic activation of chloramphenicol by rat liver microsomes. Biochemical Pharmacology 27:3, pages 335-341.
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Neal CastagnoliJr.Jr.. 1978. Stimulants. Stimulants 335 387 .
Klaus Benkert, Wolfgang Fries, Manfred Kiese & Werner Lenk. (1975) N-(9-hydroxy-9H-fluoren-2yl)-acetamide and N-(9-oxo-9H-fluoren-2yl)-acetamide: metabolites of N-(9H-fluoren-2yl)-acetamide. Biochemical Pharmacology 24:15, pages 1375-1380.
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