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Xenobiotica
the fate of foreign compounds in biological systems
Volume 4, 1974 - Issue 3
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Research Article

Complexes of Metabolites of Amphetamines with Hepatic Cytochrome P-450

Pages 133-142 | Received 13 Jul 1973, Published online: 14 Oct 2008

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Y. Joulin, M. Delaforge, H. Hoellinger, J. L. Moretti, M. Sonnier & P. Cesaro. (1990) In Vitro Covalent Binding of New Brain Tracer, Para 125 I-Amphetamine, to Rat Liver and Lung Microsomes. Drug and Chemical Toxicology 13:4, pages 325-346.
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R. Braun, U. Greeff & K. J. Netter. (1980) Indications for nitrosamide formation from the mushroom poison gyromitrin by rat liver microsomes. Xenobiotica 10:7-8, pages 557-564.
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Articles from other publishers (39)

Ye Guan, Jennifer Londoño-Salazar, Zheng Pei, Douglas R. Powell, Yihan Shao & George B. Richter-Addo. (2022) Interactions of N-hydroxyamphetamine with an iron porphyrin: A unique intramolecular H-bond probed by DFT calculations. Journal of Inorganic Biochemistry 231, pages 111779.
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Samantha M. Powell, Leonard M. Thomas & George B. Richter-Addo. (2020) The nitrosoamphetamine metabolite is accommodated in the active site of human hemoglobin: Spectroscopy and crystal structure. Journal of Inorganic Biochemistry 213, pages 111262.
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Bing Wang, Samantha M. Powell, Ye Guan, Nan Xu, Leonard M. Thomas & George B. Richter-Addo. (2017) Nitrosoamphetamine binding to myoglobin and hemoglobin: Crystal structure of the H64A myoglobin-nitrosoamphetamine adduct. Nitric Oxide 67, pages 26-29.
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A SEAGO & J W GORROD. (1987) The in-vitro metabolism of [14C]pentobarbitone and [14C]phenobarbitone by hamster liver microsomes. Journal of Pharmacy and Pharmacology 39:2, pages 84-89.
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R. Scott Obach, Odette A. Fahmi & Robert L. Walsky. 2010. Enzyme- and Transporter-Based Drug-Drug Interactions. Enzyme- and Transporter-Based Drug-Drug Interactions 473 495 .
Karl-Henrik Jönsson & Björn Lindeke. (1990) Cytochrome P-455 nm complex formation in the metabolism of phenylalkylamines. XI. Peroxygenase versus monooxygenase function of cytochrome P-450 in rat liver microsomes. Chemico-Biological Interactions 75:3, pages 267-279.
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Toshinori Yamamoto, Ritsuko Takano, Toru Egashira & Yasumitu Yamanaka. (1988) Reversible inhibition of aromatic hydroxylation of methamphetamine in rat liver microsomal preparations pretreated with methamphetamine. Biochemical Pharmacology 37:8, pages 1433-1437.
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Ulla Paulsen-Sörman, Karl-Henrik Jönsson & Björn Lindeke. (1988) Cytochrome P-455 nm complex formation in the metabolism of phenylalkylamines. IX. A comparative study with enantiomeric 2-nitroso-1-phenylpropane in microsomes and a reconstituted cytochrome P-450 system from rat liver. Chemico-Biological Interactions 67:1-2, pages 49-58.
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C.J. Schmidt, D.R. Gehlert, M.A. Peat, P.K. Sonsalla, G.R. Hanson, J.K. Wamsley & J.W. Gibb. (1985) Studies on the mechanism of tolerance to methamphetamine. Brain Research 343:2, pages 305-313.
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Marcel Delaforge, Maryse Jaouen & Daniel Mansuy. (1983) Dual effects of macrolide antibiotics on rat liver cytochrome P-450. Biochemical Pharmacology 32:15, pages 2309-2318.
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Dominique Larrey, Marina Tinel & Dominique Pessayre. (1983) Formation of inactive cytochrome P-450 Fe(II)-metabolite complexes with several erythromycin derivatives but not with josamycin and midecamycin in rats. Biochemical Pharmacology 32:9, pages 1487-1493.
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Aalt Bast & Jan Noordhoek. (1982) Spectral interaction of orphenadrine and its metabolites with oxidized and reduced hepatic microsomal cytochrome P-450 in the rat. Biochemical Pharmacology 31:17, pages 2745-2753.
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Samar F. Muakkassah, Wayne R. Bidlack & William C.T. Yang. (1981) Mechanism of the inhibitory action of isoniazid on microsomal drug metabolism. Biochemical Pharmacology 30:12, pages 1651-1658.
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Dominique Pessayre, Veronique Descatoire, Mitka Konstantinova-Mitcheva, Joao-Carlos Wandscheer, Barton Cobert, Regine Level, Jean-Pierre Benhamou, Maryse Jaouen & Daniel Mansuy. (1981) Self-induction by triacetyloleandomycin of its own transformation into a metabolite forming a stable 456 nm-absorbing complex with cytochrome P-450. Biochemical Pharmacology 30:6, pages 553-558.
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Björn Lindere, Ulla Paulsen, Christer Von Bahr & Carl-Gustav Groth. (1981) Cytochrome P-455 complex formation in the metabolism of phenylalkylamines—V. Biochemical Pharmacology 30:4, pages 388-390.
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PETER G. WISLOCKI, GERALD T. MIWA & ANTHONY Y.H. LU. 1980. Enzymatic Basis of Detoxication. Enzymatic Basis of Detoxication 135 182 .
Björn Lindeke, Ulla Paulsen & Elisabet Anderson. (1979) Cytochrome P-455 complex formation in the metabolism of phenylalkylamines—IV. Biochemical Pharmacology 28:24, pages 3629-3635.
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Robert Snyder & Herbert Remmer. (1979) Classes of hepatic microsomal mixed function oxidase inducers. Pharmacology & Therapeutics 7:2, pages 203-244.
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Masaharu Hirata, Björn Lindeke & Sten Orrenius. (1979) Cytochrome P450 product complexes and glutathione consumption produced in isolated hepatocytes by norbenzphetamine and its N-oxidized congeners. Biochemical Pharmacology 28:4, pages 479-484.
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Volker Ullrich. 1979. Blood Vessels. Blood Vessels 67 104 .
Daniel MANSUY, Philippe BEAUNE, Thierry CRESTEIL, Charles BACOT, Jean‐Claude CHOTTARD & Pierre GANS. (2008) Formation of Complexes between Microsomal Cytochrome P ‐450‐Fe(II) and Nitrosoarenes Obtained by Oxidation of Arylhydroxylamines or Reduction of Nitroarenes in situ . European Journal of Biochemistry 86:2, pages 573-579.
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Robert C. James & Michael R. Franklin. (1978) The triphasic amphetamine lethal dose curve in mice and its possible relationship to drug metabolism. Toxicology and Applied Pharmacology 44:1, pages 63-73.
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Arthur K. Cho & Jeremy Wright. (1978) Pathways of metabolism of amphetamine and related compounds. Life Sciences 22:5, pages 363-371.
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A.R. Dahl & Ernest Hodgson. (1978) The affinity of cytochrome P-450 for ethyl isocyanide: An explanation of double Soret spectra. Chemico-Biological Interactions 20:2, pages 171-180.
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Daniel Mansuy, Evelyne Rouer, Charles Bacot, Pierre Gans, Jean Claude Chottard & Jean Paul Leroux. (1978) Interaction of aliphatic N-hydroxylamines with microsomal cytochrome P450: Nature of the different derived complexes and inhibitory effects on monoxygenases activities. Biochemical Pharmacology 27:8, pages 1229-1237.
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Neal CastagnoliJr.Jr.. 1978. Stimulants. Stimulants 335 387 .
Daniel MANSUY, Jean Claude CHOTTARD & Genevieve CHOTTARD. (1977) Nitrosoalkanes as Fe(II) Ligands in the Hemoglobin and Myoglobin Complexes Formed from Nitroalkanes in Reducing Conditions. European Journal of Biochemistry 76:2, pages 617-623.
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Daniel MANSUY, Pierre GANS, Jean-Claude CHOTTARD & Jean-Francois BARTOLI. (1977) Nitrosoalkanes as Fe(II) Ligands in the 455-nm-Absorbing Cytochrome P-450 Complexes Formed from Nitroalkanes in Reducing Conditions. European Journal of Biochemistry 76:2, pages 607-615.
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John Jonsson. (2009) On the Aromatic Hydroxylation of Amphetamine in Rat Liver Microsomes and Perfused Liver Preparations: Effects of Long-term Administration. Acta Pharmacologica et Toxicologica 40, pages 517-528.
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John Jonsson. (2009) On the Aromatic Hydroxylation of Amphetamine in Rat Liver Microsomes and Perfused Liver Preparations: Effects of Long‐term Administration. Acta Pharmacologica et Toxicologica 40:4, pages 517-528.
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Michael R. Franklin. 1977. Microsomes and Drug Oxidations. Microsomes and Drug Oxidations 284 291 .
Michael R. Franklin. (1977) Inhibition of mixed-function oxidations by substrates forming reduced cytochrome P-450 metabolic-intermediate complexes. Pharmacology & Therapeutics. Part A: Chemotherapy, Toxicology and Metabolic Inhibitors 2:1, pages 227-245.
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Malcolm B. Baird, Linda S. Birnbaum, Harvey V. Samis, Harold R. Massie & Jay A. Zimmerman. (1976) Allylisopropylacetamide preferentially interacts with the phenobarbital-inducible form of rat hepatic microsomal P-450. Biochemical Pharmacology 25:21, pages 2415-2417.
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Michael R. Franklin. (1976) A new class of inhibitory cytochrome P-450 complexes formed during metabolism: A comparison with amphetamine and SKF 525-A type complexes. Chemico-Biological Interactions 14:3-4, pages 337-346.
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M R Franklin. (1976) Methylenedioxyphenyl insecticide synergists as potential human health hazards.. Environmental Health Perspectives 14, pages 29-37.
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D. Mansuy, P. Beaune, J.C. Chottard, J.F. Bartoli & P. Gans. (1976) The nature of the “455 nm absorbing complex” formed during the cytochrome P450 dependent oxidative metabolism of amphetamine. Biochemical Pharmacology 25:5, pages 609-612.
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Robert C. James & Michael R. Franklin. (1975) Comparisons of the formation of cytochrome P-450 complexes absorbing at 455 nm in rabbit and rat microsomes. Biochemical Pharmacology 24:8, pages 835-838.
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Jurgen Werringloer & Ronald W. Estabrook. (1975) Heterogeneity of liver microsomal cytochrome P-450: The spectral characterization of reactants with reduced cytochrome P-450. Archives of Biochemistry and Biophysics 167:1, pages 270-286.
Crossref
E. Änggård, T. Lewander & L.-M. Gunne. 1977. Drug Addiction II. Drug Addiction II 3 275 .

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