Citations (58)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (5)
Christopher J. H. Porter & William N. Charman. (2001) LIPID-BASED FORMULATIONS FOR ORAL ADMINISTRATION: OPPORTUNITIES FOR BIOAVAILABILITY ENHANCEMENT AND LIPOPROTEIN TARGETING OF LIPOPHILIC DRUGS. Journal of Receptors and Signal Transduction 21:2-3, pages 215-257.
Read now
Read now
T. Ichihashi, H. Kinoshita & H. Yamada. (1991) Absorption and disposition of epithiosteroids in rats (2): Avoidance of first-pass metabolism of mepitiostane by lymphatic absorption. Xenobiotica 21:7, pages 873-880.
Read now
Read now
M. Mishima, S. Kobayashi, S. Abe & C. Yamato. (1990) Metabolic fate of indometacin farnesil, a prodrug of indomethacin: characteristic biotransformation of indometacin farnesil in rats. Xenobiotica 20:2, pages 135-146.
Read now
Read now
R. C. Grimus & I. Schuster. (1984) The role of the lymphatic transport in the enteral absorption of naftifine by the rat. Xenobiotica 14:4, pages 287-294.
Read now
Read now
J. D. Kamp & H.-G. Neumann. (1975) Absorption of Carcinogens into the Thoracic Duct Lymph of the Rat: Aminostilbene Derivatives and 3-Methylcholanthrene. Xenobiotica 5:12, pages 717-727.
Read now
Read now
Articles from other publishers (53)
Yenju Chu, Chaolong Qin, Wanshan Feng, Charles Sheriston, Yu Jane Khor, Concepción Medrano-Padial, Birgit E. Watson, Teddy Chan, Binhua Ling, Michael J. Stocks, Peter M. Fischer & Pavel Gershkovich. (2021) Oral administration of tipranavir with long-chain triglyceride results in moderate intestinal lymph targeting but no efficient delivery to HIV-1 reservoir in mesenteric lymph nodes. International Journal of Pharmaceutics 602, pages 120621.
Crossref
Crossref
Pavel Ryšánek, Tomáš Grus, Martin Šíma & Ondřej Slanař. (2020) Lymphatic Transport of Drugs after Intestinal Absorption: Impact of Drug Formulation and Physicochemical Properties. Pharmaceutical Research 37:9.
Crossref
Crossref
William N. Charman & Valentino J. StellaTetsuo Noguchi. 2019. Lymphatic Transport of Drugs. Lymphatic Transport of Drugs
211
232
.
René Holm, Anette Müllertz & Huiling Mu. (2013) Bile salts and their importance for drug absorption. International Journal of Pharmaceutics 453:1, pages 44-55.
Crossref
Crossref
Suzanne M. Caliph, Natalie L. Trevaskis, William N. Charman & Christopher J.H. Porter. (2012) Intravenous Dosing Conditions May Affect Systemic Clearance for Highly Lipophilic Drugs: Implications for Lymphatic Transport and Absolute Bioavailability Studies. Journal of Pharmaceutical Sciences 101:9, pages 3540-3546.
Crossref
Crossref
. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety
1
16
.
. 2002. The MAK-Collection for Occupational Health and Safety. The MAK-Collection for Occupational Health and Safety
1
318
.
Jaime A. Yáñez, Stephen W.J. Wang, Ian W. Knemeyer, Mark A. Wirth & Kevin B. Alton. (2011) Intestinal lymphatic transport for drug delivery. Advanced Drug Delivery Reviews 63:10-11, pages 923-942.
Crossref
Crossref
Teruhisa Ichihashi, Haruki Kinoshita, Yasushi Takagishi & Hideo Yamada. (1992) Effect of Bile on Absorption of Mepitiostane by the Lymphatic System in Rats. Journal of Pharmacy and Pharmacology 44:7, pages 565-569.
Crossref
Crossref
Teruhisa Ichihashi, Haruki Kinoshita, Yasushi Takagishi & Hideo Yamada. (1992) Effect of Oily Vehicles on Absorption of Mepitiostane by the Lymphatic System in Rats. Journal of Pharmacy and Pharmacology 44:7, pages 560-564.
Crossref
Crossref
S G Woolfrey, K J Palin & S S Davis. (1989) The effect of Miglyol 812 oil on the oral absorption of propranolol in the rat. Journal of Pharmacy and Pharmacology 41:8, pages 579-581.
Crossref
Crossref
M Cheema, K J Palin & S S Davis. (1987) Lipid vehicles for intestinal lymphatic drug absorption. Journal of Pharmacy and Pharmacology 39:1, pages 55-56.
Crossref
Crossref
K J Palin, C G Wilson, S S Davis & A J Phillips. (1982) The effect of oils on the lymphatic absorption of DDT. Journal of Pharmacy and Pharmacology 34:11, pages 707-710.
Crossref
Crossref
K Palin, S S Davis, A J Phillips, D Whalley & C G Wilson. (1980) Effect of Lipid Vehicles on the Oral Absorption of A Model Compound (Ddt). Journal of Pharmacy and Pharmacology 32:Supplement_1, pages 62P-62P.
Crossref
Crossref
Natalie L. Trevaskis, William N. Charman & Christopher J. H. Porter. (2010) Targeted Drug Delivery to Lymphocytes: A Route to Site-Specific Immunomodulation?. Molecular Pharmaceutics 7:6, pages 2297-2309.
Crossref
Crossref
Andrew G. Smith. 2010. Hayes' Handbook of Pesticide Toxicology. Hayes' Handbook of Pesticide Toxicology
1975
2032
.
Natalie L. Trevaskis, David M. Shackleford, William N. Charman, Glenn A. Edwards, Anne Gardin, Silke Appel-Dingemanse, Olivier Kretz, Bruno Galli & Christopher J. H. Porter. (2009) Intestinal Lymphatic Transport Enhances the Post-Prandial Oral Bioavailability of a Novel Cannabinoid Receptor Agonist Via Avoidance of First-Pass Metabolism. Pharmaceutical Research 26:6, pages 1486-1495.
Crossref
Crossref
Natalie L. Trevaskis, William N. Charman & Christopher J.H. Porter. (2008) Lipid-based delivery systems and intestinal lymphatic drug transport: A mechanistic update. Advanced Drug Delivery Reviews 60:6, pages 702-716.
Crossref
Crossref
Christopher J. H. Porter, Natalie L. Trevaskis & William N. Charman. (2007) Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs. Nature Reviews Drug Discovery 6:3, pages 231-248.
Crossref
Crossref
Natalie L. Trevaskis, Christopher J.H. Porter & William N. Charman. (2006) AN EXAMINATION OF THE INTERPLAY BETWEEN ENTEROCYTE-BASED METABOLISM AND LYMPHATIC DRUG TRANSPORT IN THE RAT. Drug Metabolism and Disposition 34:5, pages 729-733.
Crossref
Crossref
Natalie L. Trevaskis, Patrick Tso, Therese Rider, William N. Charman, Christopher J.H. Porter & Ronald Jandacek. (2005) Tissue uptake of DDT is independent of chylomicron metabolism. Archives of Toxicology 80:4, pages 196-200.
Crossref
Crossref
Natalie L. Trevaskis, Christopher J. H. Porter & William N. Charman. (2005) Bile Increases Intestinal Lymphatic Drug Transport in the Fasted Rat. Pharmaceutical Research 22:11, pages 1863-1870.
Crossref
Crossref
Christopher Porter & William Charman. 2001. Drug Targeting Technology. Drug Targeting Technology.
Andrew G. Smith. 2001. Handbook of Pesticide Toxicology. Handbook of Pesticide Toxicology
1305
1355
.
Françoise Nielloud & Gilberte Marti-MestresDuncan Craig, Manisha Patel & Marianne Ashford. 2000. Pharmaceutical Emulsions and Suspensions. Pharmaceutical Emulsions and Suspensions
323
360
.
Kenneth A Koeplinger, Thomas J Raub, Guy E Padbury & Zhiyang Zhao. (1999) Equilibrium distribution of HIV antiviral drugs into human peripheral blood mononuclear cells (PBMC) is controlled by free drug concentration in the extracellular medium. Journal of Pharmaceutical and Biomedical Analysis 19:3-4, pages 399-411.
Crossref
Crossref
Gloria Y Kwei, Linda B Novak, Lisa H Hettrick, Elisabeth R Reiss, Eva K Fong, Timothy V Olah & Alice E Loper. (1998) Lymphatic uptake of MK-386, a sterol 5α-reductase inhibitor, from aqueous and lipid formulations. International Journal of Pharmaceutics 164:1-2, pages 37-44.
Crossref
Crossref
William N. Charman & Christopher J.H. Porter. (1996) Lipophilic prodrugs designed for intestinal lymphatic transport. Advanced Drug Delivery Reviews 19:2, pages 149-169.
Crossref
Crossref
. 1994. Neglected Factors in Pharmacology and Neuroscience Research - Biopharmaceutics, Animal characteristics Maintenance, Testing conditions. Neglected Factors in Pharmacology and Neuroscience Research - Biopharmaceutics, Animal characteristics Maintenance, Testing conditions
59
115
.
Shozo Muranishi, Akira Yamamoto & Hiroaki Okada. 1993. Biological Barriers to Protein Delivery. Biological Barriers to Protein Delivery
199
227
.
S.G. Barnwell, T. Laudanski, M.J. Story, C.B. Mallinson, R.J. Harris, S.K. Cole, M. Keating & D. Attwood. (1992) Improved oral bioavailability of propranolol in healthy human volunteers using a liver bypass drug delivery system containing oleic acid. International Journal of Pharmaceutics 88:1-3, pages 423-432.
Crossref
Crossref
Teruhisa Ichihashi, Yasushi Takagishi, Kiyohisa Uchida & Hideo Yamada. (1992) Colonic Absorption of Menaquinone-4 and Menaquinone-9 in Rats. The Journal of Nutrition 122:3, pages 506-512.
Crossref
Crossref
R.A. Myers & V.J. Stella. (1992) Factors affecting the lymphatic transport of penclomedine (NSC-338720), a lipophilic cytotoxic drug: Comparison to DDT and hexachlorobenzene. International Journal of Pharmaceutics 80:1-3, pages 51-62.
Crossref
Crossref
D.G. White, M.J. Story & S.G. Barnwell. (1991) An experimental animal model for studying the effects of a novel lymphatic drug delivery system for propranolol. International Journal of Pharmaceutics 69:2, pages 169-174.
Crossref
Crossref
SHOZO MURANISHI. 1991.
1
38
.
J. A. Barrowman & P. Tso. 2011. Comprehensive Physiology. Comprehensive Physiology
1733
1777
.
Peter A. Van Veld, John S. Patton & Richard F. Lee. (1988) Effect of preexposure to dietary benzo[a]pyrene (BP) on the first-pass metabolism of BP by the intestine of toadfish (Opsanus tau): in vivo studies using portal vein-catheterized fish. Toxicology and Applied Pharmacology 92:2, pages 255-265.
Crossref
Crossref
R. Schulz & D. Winne. (1987) Relationship between antipyrine absorption and blood flow rate in rat jejunum, ileum, and colon. Naunyn-Schmiedeberg's Archives of Pharmacology 335:1, pages 97-102.
Crossref
Crossref
W.N.A. Charman & V.J. Stella. (1986) Estimating the maximal potential for intestinal lymphatic transport of lipophilic drug molecules. International Journal of Pharmaceutics 34:1-2, pages 175-178.
Crossref
Crossref
Walter G. Gowan & Salomon Stavchansky. (1986) The effect of solvent composition upon the blood and lymph levels of phenytoin in rats after gastric administration. International Journal of Pharmaceutics 28:2-3, pages 193-199.
Crossref
Crossref
John S. Patton. 1986. Human Lactation 2. Human Lactation 2
475
497
.
. (2016) 1 Final Report on the Safety Assessment of Stearyl Alcohol, Oleyl Alcohol, and Octyl Dodecanol. Journal of the American College of Toxicology 4:5, pages 1-29.
Crossref
Crossref
Koichiro Hirano & C. Anthony Hunt. (1985) Lymphatic Transport of Liposome-Encapsulated Agents: Effects of Liposome Size Following Intraperitoneal Administration. Journal of Pharmaceutical Sciences 74:9, pages 915-921.
Crossref
Crossref
T. Noguchi, W.N.A. Charman & V.J. Stella. (1985) The effect of drug lipophilicity and lipid vehicles on the lymphatic absorption of various testosterone esters. International Journal of Pharmaceutics 24:2-3, pages 173-184.
Crossref
Crossref
Clarence T. Ueda, Michel Lemaire, Guy Gsell & Kurt Nussbaumer. (2006) Intestinal lymphatic absorption of cyclosporin a following oral administration in an olive oil solution in rats. Biopharmaceutics & Drug Disposition 4:2, pages 113-124.
Crossref
Crossref
R.F. Addison. (1982) Organochlorine compounds and marine lipid. Progress in Lipid Research 21:1, pages 47-71.
Crossref
Crossref
Rajendra S. Chhabra. (1979) Intestinal absorption and metabolism of xenobiotics. Environmental Health Perspectives 33, pages 61-69.
Crossref
Crossref
A Kuksis, N A Shaikh & A G Hoffman. (1979) Lipid absorption and metabolism.. Environmental Health Perspectives 33, pages 45-55.
Crossref
Crossref
. (1979) Benzoic acid. Food and Cosmetics Toxicology 17, pages 715-722.
Crossref
Crossref
D. Wine. (1979) Influence of blood flow on intestinal absorption of drugs and nutrients. Pharmacology & Therapeutics 6:2, pages 333-393.
Crossref
Crossref
D.L.J. Opdyke. (1979) Monographs on fragrance raw materials. Food and Cosmetics Toxicology 17:4, pages 357-390.
Crossref
Crossref
M.J. Patterson, K.F. Ilett, B.W. Madsen & L.B. Jellett. (1978) The effect of food on the disposition of radioactivity in rats after administration of 14C-haloperidol. Pharmacological Research Communications 10:2, pages 111-125.
Crossref
Crossref
Robert L. Smith & P. Millburn. 1976. Mechanisms of Toxicity and Metabolism. Mechanisms of Toxicity and Metabolism
77
88
.