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Xenobiotica
the fate of foreign compounds in biological systems
Volume 4, 1974 - Issue 1
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Research Article

Pharmacokinetics and Metabolism of [3H] Thebaine

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Pages 17-32 | Received 26 Jun 1973, Published online: 22 Sep 2008

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Allister Vale$suffix/text()$suffix/text(). (2023) Poisoning from non-food grade poppy seeds. Clinical Toxicology 61:9, pages 625-628.
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Rowena Penafiel, David Yoo, Claire Turner, Jared A. Brown, Catherine McDonald, Jason Tran, Vanessa Shaw & Darren M. Roberts. (2023) Toxicokinetics of thebaine in those consuming non-food grade poppy seeds as a tea. Clinical Toxicology 61:9, pages 644-648.
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G. Mikus, A. A. Somogyi, F. Bochner & M. Eichelbaum. (1991) Thebaine O-demethylation to oripavine: Genetic differences between two rat strains. Xenobiotica 21:11, pages 1501-1509.
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A. L. Misra, R. B. Pontani & N. L. Vadlamani. (1979) Metabolism of norcocaine, N-hydroxy norcocaine and cocaine-N-oxide in the rat. Xenobiotica 9:3, pages 189-199.
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A. L. Misra, M. N. Patel, V. R. Alluri, S. J. Mulé & P. K. Nayak. (1976) Disposition and Metabolism of [3HCocaine in Acutely and Chronically treated Dogs. Xenobiotica 6:9, pages 537-552.
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A. L. Misra, R. Bloch, N. L. Vadlamani & S. J. Mulé. (1975) Laevo-[1-3H]Methadone Disposition in Tolerant Dogs. Xenobiotica 5:4, pages 237-244.
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A. L. Misra, R. B. Pontani & S. J. Mulé. (1974) [2-14C] Amobarbital Metabolism in Tolerant Rats. Xenobiotica 4:7, pages 409-423.
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Kuntal Manna, Waikhom Somraj Singh, Sanchari Goswami, Abu Md Ashif Ikbal, Amlanjyoti Rajkhowa & Bikash Debnath. (2023) Metabolites Study of Experimental Plant Derived Alkaloids: A Review. The Natural Products Journal 13:7.
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Nadine Theofel, Philipp Möller, Elke Vejmelka, Claus Kramer, Michael Tsokos & Stefan Scholtis. (2022) A Fatal Case Report Resulting from the Abuse of the Designer Benzodiazepines Clonazolam and Flualprazolam in Conjunction with Dried Opium Poppy Pods. Journal of Analytical Toxicology 46:9, pages e285-e290.
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Hauke Reimann, Ezgi Eylül Bankoglu, Helga Stopper & Henning Hintzsche. (2021) In vitro evaluation of chromosomal damage and DNA strand breaks after treatment with the poppy seed alkaloid thebaine. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 870-871, pages 503393.
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Andreas Eisenreich, Benjamin Sachse, Rainer Gürtler, Birgit Dusemund, Oliver Lindtner & Bernd Schäfer. (2020) What do we know about health risks related to thebaine in food?. Food Chemistry 309, pages 125564.
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Bikash Debnath, Waikhom Somraj Singh, Manik Das, Sanchari Goswami, Mahesh Kumar Singh, Debasish Maiti & Kuntal Manna. (2018) Role of plant alkaloids on human health: A review of biological activities. Materials Today Chemistry 9, pages 56-72.
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Helle Katrine Knutsen, Jan Alexander, Lars Barregård, Margherita Bignami, Beat Brüschweiler, Sandra Ceccatelli, Bruce Cottrill, Michael Dinovi, Lutz Edler, Bettina Grasl‐Kraupp, Christer Hogstrand, Laurentius (Ron) Hoogenboom, Carlo Stefano Nebbia, Isabelle P Oswald, Annette Petersen, Martin Rose, Alain‐Claude Roudot, Tanja Schwerdtle, Günter Vollmer, Heather Wallace, Diane Benford, Girolamo Calò, Albert Dahan, Birgit Dusemund, Patrick Mulder, Éva Németh‐Zámboriné, Davide Arcella, Katleen Baert, Claudia Cascio, Sara Levorato, Marijke Schutte & Christiane Vleminckx. (2018) Update of the Scientific Opinion on opium alkaloids in poppy seeds. EFSA Journal 16:5.
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Alexandra Maas, Burkhard Madea & Cornelius Hess. (2018) Confirmation of recent heroin abuse: Accepting the challenge. Drug Testing and Analysis 10:1, pages 54-71.
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A. Laux-Biehlmann, J. Mouheiche, J. Vérièpe & Y. Goumon. (2013) Endogenous morphine and its metabolites in mammals: History, synthesis, localization and perspectives. Neuroscience 233, pages 95-117.
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. (2011) Scientific Opinion on the risks for public health related to the presence of opium alkaloids in poppy seeds. EFSA Journal 9:11.
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A L MisraP K NayakR BlochS J Mulé. (1975) Estimation and disposition of [3H]benzoylecgonine and pharmacological activity of some cocaine metabolites. Journal of Pharmacy and Pharmacology 27:10, pages 784-786.
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A L Misra, N L Vadlamani, R B Pontani & S J Mule. (1974) Some physicochemical and pharmacological properties of morphine-2,3-quinone, the morphine metabolite in the rat brain. Journal of Pharmacy and Pharmacology 26:12, pages 990-992.
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Nadja GrobeMarc LamshöftRobert G. Orth, Birgit Dräger, Toni M. KutchanMeinhart H. ZenkMichael Spiteller. (2010) Urinary excretion of morphine and biosynthetic precursors in mice. Proceedings of the National Academy of Sciences 107:18, pages 8147-8152.
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Fedor Medzihradsky, Paul J. Emmerson & Carol A. Mousigian. (1992) Lipophilicity of opioids determined by a novel micromethod. Journal of Pharmacological and Toxicological Methods 27:2, pages 67-69.
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Yasushi YAMAZOE, Hiroaki NUMATA & Tomoji YANAGITA. (1981) THEBAINE METABOLITES IN THE URINE OF RHESUS MONKEYS. Japanese Journal of Pharmacology 31:3, pages 433-442.
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S.J. Mulé & A.L. Misra. (1978) PHARMACOLOGY OF ?-?-ACETYLMETHADOL (LAAM) IN SUBHUMAN PRIMATES. Annals of the New York Academy of Sciences 311:1 Recent Develo, pages 199-213.
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A. L. Misra, N. L. Vadlamani & R. B. Pontani. (1977) Differential effects of opiates on the incorporation of [14C] thiamine in the central nervous system of the rat. Experientia 33:3, pages 372-374.
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A. L. Misra, R. B. Pontani & S. J. Mule'. (1976) [3H]-Norcocaine and [3H]-pseudococaine: Effect of N-demethylation and C2-epimerization of cocaine on its pharmacokinetics in the rat. Experientia 32:7, pages 895-897.
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John K. Haleblian & Frank W. Goodhart. (1975) Pharmaceutical Sciences—1974: Literature Review of Pharmaceutics. Journal of Pharmaceutical Sciences 64:7, pages 1085-1148.
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A. L. Misra, P. K. Nayak, M. N. Patel, N. L. Vadlamani & S. J. Mulé. (1974) Identification of norcocaine as a metabolite of [3H]-cocaine in rat brain. Experientia 30:11, pages 1312-1314.
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