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Xenobiotica
the fate of foreign compounds in biological systems
Volume 4, 1974 - Issue 7
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Research Article

The Metabolic Fate of the Coronary Dilator 4-(3,4,5-Trimethoxycinnamoyl)-1-(N-Isopropylcarbamoylmethyl)- Piperazine in the Rat, Dog and Man

L. F. Chasseaud Department of Metabolism and Pharmacokinetics, Huntingdon Research Centre, Huntingdon, UK
,
D. R. Hawkins Department of Metabolism and Pharmacokinetics, Huntingdon Research Centre, Huntingdon, UK
,
B. J. Fry Department of Metabolism and Pharmacokinetics, Huntingdon Research Centre, Huntingdon, UK
,
J. D. Lewis Department of Metabolism and Pharmacokinetics, Huntingdon Research Centre, Huntingdon, UK
,
V. H. Saggers Department of Metabolism and Pharmacokinetics, Huntingdon Research Centre, Huntingdon, UK
&
I. P. Sword Department of Metabolism and Pharmacokinetics, Huntingdon Research Centre, Huntingdon, UK
Pages 393-407 | Received 01 Nov 1973, Published online: 22 Sep 2008

Citations (9)

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Read on this site (8)

B. A. John, L. F. Chasseaud, S. G. Wood & P. Forlot. (1992) Metabolism of the anti-psoriatic agent 5-methoxypsoralen in humans: comparison with rat and dog. Xenobiotica 22:11, pages 1339-1351.
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Bruce Clark, Dennis A. Smith & John Caldwell. (1984) Pharmacokinetics and Toxicity Testing. CRC Critical Reviews in Toxicology 12:4, pages 343-385.
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S. G. Wood, B. A. John, L. F. Chasseaud, I. Johnstone, S. R. Biggs, D. R. Hawkins, J. G. Priego, A. Darragh & R. F. Lambe. (1983) The metabolism of the anti-inflammatory drug eterylate in rat, dog and man. Xenobiotica 13:12, pages 731-742.
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S. G. Wood, D. Kirkpatrick, A. J. S. Jackson, D. R. Hawkins, W. H. Down, L. F. Chasseaud, S. R. Biggs & A. Darragh. (1982) The metabolism of the hypolipidaemic drug sultosilic acid in rat, dog and man. Xenobiotica 12:3, pages 165-176.
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B. C. Mayo, S. R. Biggs, L. F. Chasseaud, D. R. Hawkins, A. Darragh & D. A. O'kelly. (1980) The metabolic fate of Sormodren (bornaprine hydrochloride) in animals and humans. Xenobiotica 10:12, pages 873-888.
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R. Girkin, G. A. Baldock, L. F. Chasseaud, M. Hümpel, D. R. Hawkins & B. C. Mayo. (1980) The absorption, distribution and excretion of [14C]lormetazepam in dogs, rabbits, rats and rhesus monkeys. Xenobiotica 10:6, pages 401-411.
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D. R. Hawkins, D. H. Moore & L. F. Chasseaud. (1977) The Metabolism of the Neuroleptic Agent 1-(4′ -Fluorophenyl)-4-(cyclohexyl-1′-piperazinyl-4′-carboxylate)-butan-1-one Hydrochloride in Rats and Man. Xenobiotica 7:5, pages 315-325.
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B. D. Cameron, L. F. Chasseaud, D. R. Hawkins & T. Taylor. (1976) The Metabolic Fate of the Coronary Vasodilator 4-(3,4,5-Trimethoxycinnamoyl)-l-(N-pyrrolidino-carbonylmethyl)piperazine (Cinepazide) in the Rat, Dog and Man. Xenobiotica 6:7, pages 441-455.
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Articles from other publishers (1)

D. R. Hawkins, K. T. Weston, L. F. Chasseaud, A. Darragh & A. O’kelly. (1980) The absorption and excretion of the peripheral vasodilator14C-mecinarone, (14C-6809 MD) in rat, dog and man. European Journal of Drug Metabolism and Pharmacokinetics 5:3, pages 135-143.
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