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Xenobiotica
the fate of foreign compounds in biological systems
Volume 4, 1974 - Issue 7
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Research Article

Entero-bacterial Formation of Cyclohexylamine in Rats Ingesting Cyclamate

M. H. Bickel Medizinisch-chemisches Institut, University of Berne, Berne, Switzerland
,
B. Burkard Medizinisch-chemisches Institut, University of Berne, Berne, Switzerland
,
E. Meier-strasser Medizinisch-chemisches Institut, University of Berne, Berne, Switzerland
&
M. Van Den Broek-Boot Medizinisch-chemisches Institut, University of Berne, Berne, Switzerland
Pages 425-439 | Received 11 Dec 1973, Published online: 22 Sep 2008

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I. R. Rowland. (1988) Factors Affecting Metabolic Activity of the Intestinal Microflora. Drug Metabolism Reviews 19:3-4, pages 243-261.
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Barbara A. Bopp, Robert C. Sonders, James W. Kesterson & A. G. Renwick. (1986) Toxicological aspects of cyclamate and cyclohexylamine. CRC Critical Reviews in Toxicology 16:3, pages 213-306.
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A. G. Renwick. (1986) The metabolism of intense sweeteners. Xenobiotica 16:10-11, pages 1057-1071.
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Ian R. Rowland, Anthony K. Mallett & Alan Wise. (1985) The Effect of Diet on the Mammalian Gut Flora and Its Metabolic Activities. CRC Critical Reviews in Toxicology 16:1, pages 31-103.
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Sik Yu So, Qinglong Wu & Tor Savidge. 2023. Present Knowledge in Food Safety. Present Knowledge in Food Safety 812 828 .
Sandrine P Claus, Hervé Guillou & Sandrine Ellero-Simatos. (2016) The gut microbiota: a major player in the toxicity of environmental pollutants?. npj Biofilms and Microbiomes 2:1.
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Marco Scheurer, Heinz-Jürgen Brauch & Frank Thomas Lange. 2014. Transformation Products of Emerging Contaminants in the Environment. Transformation Products of Emerging Contaminants in the Environment 525 544 .
K Walton, R Walker, J.J.M van de Sandt, J.V Castell, A.G.A.A Knapp, G Kozianowski, M Roberfroid & B Schilter. (1999) The application of in vitro data in the derivation of the Acceptable Daily Intake of food additives. Food and Chemical Toxicology 37:12, pages 1175-1197.
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Marie E. Coates & R. Walker. (2007) Interrelationships between the Gastrointestinal Microflora and Non-Nutrient Components of the Diet. Nutrition Research Reviews 5:1, pages 85-96.
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Roy FullerIan R. Rowland. 1992. Probiotics. Probiotics 29 53 .
Dianne M. Creasy, Graham R. Ford & Tim J.B. Gray. (1990) The morphogenesis of cyclohexylamine-induced testicular atrophy in the rat: In vivo and in vitro studies. Experimental and Molecular Pathology 52:2, pages 155-169.
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MARILYN C. HENDERSON. 1990. Nitrogen and Phosphorus Solvents. Nitrogen and Phosphorus Solvents 24 37 .
A. Roberts & A.G. Renwick. (1989) The pharmacokinetics and tissue concentrations of cyclohexylamine in rats and mice. Toxicology and Applied Pharmacology 98:2, pages 230-242.
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A. Roberts, A.G. Renwick, G. Ford, D.M. Creasy & I. Gaunt. (1989) The metabolism and testicular toxicity of cyclohexylamine in rats and mice during chronic dietary administration. Toxicology and Applied Pharmacology 98:2, pages 216-229.
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A.G. RENWICK. 1988. Role of the Gut Flora in Toxicity and Cancer. Role of the Gut Flora in Toxicity and Cancer 175 206 .
M.E. COATES, B.S. DRASAR, A.K. MALLETT & I.R. ROWLAND. 1988. Role of the Gut Flora in Toxicity and Cancer. Role of the Gut Flora in Toxicity and Cancer 1 21 .
A.K. Mallett, I.R. Rowland, C.A. Bearne, R. Purchase & S.D. Gangolli. (1985) Metabolic adaptation of rat faecal microflora to cyclamate in vitro. Food and Chemical Toxicology 23:12, pages 1029-1034.
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A.G. Renwick. (1985) The fate of intense sweeteners in the body. Food Chemistry 16:3-4, pages 281-301.
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A K Mallett, C A Bearne & I R Rowland. (1983) Metabolic activity and enzyme induction in rat fecal microflora maintained in continuous culture. Applied and Environmental Microbiology 46:3, pages 591-595.
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PETER GOLDMAN. 1983. Human Intestinal Microflora in Health and Disease. Human Intestinal Microflora in Health and Disease 241 263 .
A.G. Renwick. 1982. Presystemic Drug Elimination. Presystemic Drug Elimination 3 28 .
William J. Spillane & G. Anthony Benson. (1978) Metabolic Studies of the Nonnutritive Sweeteners Cyclopentylmethylsulfamate and Cyclopentylsulfamate: Determination of Metabolites in Rat Urine. Journal of Pharmaceutical Sciences 67:2, pages 226-228.
Crossref
A. Kinawi & H. Kia. (1978) Zur Umsetzung von Cyclohexylsulfamins?ure (Cyclamat) mit salpetriger S?ure in w??riger HCl-L?sung, isoliertem menschlichen Magensaft und Urin. Clinical Chemistry and Laboratory Medicine 16:6.
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R.A. PRINS. 1978. Nutrition and Drug Interrelations. Nutrition and Drug Interrelations 189 251 .

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