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Xenobiotica
the fate of foreign compounds in biological systems
Volume 5, 1975 - Issue 8
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Research Article

Properties of Benzpyrene Hydroxylase from Human Liver and Comparison with the Rat, Rabbit and Guinea-pig Enzymes

Olavi Pelkonen Departments of Pharmacology and Surgery, University of Oulu, SF-90220, Oulu, Finland, 22
,
Eero H. Kaltiala Departments of Pharmacology and Surgery, University of Oulu, SF-90220, Oulu, Finland, 22
,
Niilo T. Kärki Departments of Pharmacology and Surgery, University of Oulu, SF-90220, Oulu, Finland, 22
,
Kari Jalonen Departments of Pharmacology and Surgery, University of Oulu, SF-90220, Oulu, Finland, 22
&
Kalevi Pyörälä Departments of Pharmacology and Surgery, University of Oulu, SF-90220, Oulu, Finland, 22; Finnish Red Cross Blood Transfusion Service, SF-00310, Helsinki, Finland, 31
Pages 501-509 | Received 18 Sep 1974, Published online: 14 Oct 2008

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Cheryl A. Mugford & Gregory L. Kedderis. (1998) Sex-Dependent Metabolism of Xenobiotics. Drug Metabolism Reviews 30:3, pages 441-498.
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M. M. Husain, A. Kumar, H. Mukhtar & C. R. Krishnamurti. (1981) Xenobiotic biotransformation in wild birds: Activity, induction, characterization and comparison with rat and mouse microsomal enzymes. Xenobiotica 11:11, pages 785-793.
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E J Calabrese. (1988) Comparative biology of test species.. Environmental Health Perspectives 77, pages 55-62.
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Edward J. Calabrese. 1988. Carcinogen Risk Assessment. Carcinogen Risk Assessment 115 122 .
Olavi Pelkonen & Eero A. Sotaniemi. (1987) Environmental factors of enzyme induction and inhibition. Pharmacology & Therapeutics 33:1, pages 115-120.
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Edward J. Calabrese. (1986) Animal Extrapolation and the Challenge of Human Heterogeneity. Journal of Pharmaceutical Sciences 75:11, pages 1041-1046.
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O. Pelkonen, M. Pasanen, H. Kuha, B. Gachalyi, M. Kairaluoma, EA Sotaniemi, SS Park, FK Friedman & HV Gelboin. (1986) The effect of cigarette smoking on 7-ethoxyresorufin O-deethylase and other monooxygenase activities in human liver: analyses with monoclonal antibodies.. British Journal of Clinical Pharmacology 22:2, pages 125-134.
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O Pelkonen, EA Sotaniemi & JT Ahokas. (1985) Coumarin 7-hydroxylase activity in human liver microsomes. Properties of the enzyme and interspecies comparisons.. British Journal of Clinical Pharmacology 19:1, pages 59-66.
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Olavi Pelkonen, Kirsi Vähäkangas, Niilo T. Kärki & Eero A. Sotaniemi. (2016) Genetic and Environmental Regulation of Aryl Hydrocarbon Hydroxylase in Man: Studies with Liver, Lung, Placenta, and Lymphocytes. Toxicologic Pathology 12:3, pages 256-260.
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P. Lindström-Seppä, U. Koivusaari & O. Hänninen. (1983) Metabolism of foreign compounds in freshwater crayfish (Astacus astacus L.) tissues. Aquatic Toxicology 3:1, pages 35-46.
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P. Sanz, P. Villar & M. Repetto. 1983. Toxicology in the Use, Misuse, and Abuse of Food, Drugs, and Chemicals. Toxicology in the Use, Misuse, and Abuse of Food, Drugs, and Chemicals 115 120 .
W. Klinger. (1982) Biotransformation of drugs and other xenobiotics during postnatal development. Pharmacology & Therapeutics 16:3, pages 377-429.
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P. Lesca, P. Beaune & B. Monsarrat. (1981) Ellipticines and human liver microsomes: Spectral interaction with cytochrome P-450 and hydroxylation. Inhibition of aryl hydrocarbon metabolism and mutagenicity. Chemico-Biological Interactions 36:3, pages 299-309.
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M. J. Brodie, A. R. Boobis, C. J. Bulpitt & D. S. Davies. (1981) Influence of liver disease and environmental factors on hepatic monooxygenase activity in vitro. European Journal of Clinical Pharmacology 20:1, pages 39-46.
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Theodore L. McLemore & R. Russell Martin. 1981. Lung Cancer 1. Lung Cancer 1 1 34 .
AR Boobis, MJ Brodie, GC Kahn, DR Fletcher, JH Saunders & DS Davies. (2012) Monooxygenase activity of human liver in microsomal fractions of needle biopsy specimens.. British Journal of Clinical Pharmacology 9:1, pages 11-19.
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S. S. Rossi & J. W. Anderson. (1978) Petroleum hydrocarbon resistance in the marine wormNeanthes arenaceodentata (polychaeta: Annelida), induced by chronic exposure to no. 2 fuel oil. Bulletin of Environmental Contamination and Toxicology 20:1, pages 513-521.
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Jacquelene M. Fysh & Allan B. Okey. (1978) Aryl hydrocarbon (benzo[a]pyrene) hydroxylase development in rat mammary tissue. Biochemical Pharmacology 27:24, pages 2968-2972.
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Olavi Pelkonen, Eero Sotaniemi & Risto Mokka. (1977) The in vitro oxidative metabolism of benzo(a)pyrene in human liver measured by different assays. Chemico-Biological Interactions 16:1, pages 13-22.
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P. Arvela, N. T. Kärki & R. O. Pelkonen. (1976) Lipoperoxidation rates and drug-oxidizing enzyme activities in the liver and placenta of some mammal species during the perinatal period. Experientia 32:10, pages 1311-1313.
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C. Harris. (1976) Chemical Carcinogenesis and Experimental Models Using Human Tissues. Beiträge zur Pathologie 158:4, pages 389-404.
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