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Xenobiotica
the fate of foreign compounds in biological systems
Volume 5, 1975 - Issue 12
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Research Article

Metabolites of Pindolol in Different Animal Species

J. R. Kiechel Department of Pharmaceutical Research and Development, Sandoz Ltd., Basel, Switzerland
,
P. Niklaus Department of Pharmaceutical Research and Development, Sandoz Ltd., Basel, Switzerland
,
E. Schreier Department of Pharmaceutical Research and Development, Sandoz Ltd., Basel, Switzerland
&
H. Wagner Department of Pharmaceutical Research and Development, Sandoz Ltd., Basel, Switzerland; Biological and Medical Research Division, Sandoz Ltd., Basel, Switzerland
Pages 741-754 | Received 21 Mar 1975, Published online: 14 Oct 2008

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André Guillouzo, Jean-Marc Bégué, Gérard Maurer & Patrick Koch. (1988) Identification of metabolic pathways of pindolol and fluperlapine in adult human hepatocyte cultures. Xenobiotica 18:2, pages 131-139.
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G. Maurer, P. Donatsch, H. Galliker, J. R. Kiechel & J. Meier. (1981) Pindolol: Disposition and metabolism in rhesus monkeys after chronic treatment. Xenobiotica 11:1, pages 33-41.
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Articles from other publishers (18)

Magdalena Ogrodowczyk, Barbara Marciniec & Piotr Kachlicki. (2014) Spectroscopic analysis of pindolol irradiated in the solid state. Open Chemistry 12:1, pages 60-66.
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Weber Heinz. 2005. The Laboratory Primate. The Laboratory Primate 259 272 .
M. S. Leloux & R. A. A. Maes. (1990) The use of electron impact and positive chemical ionization mass spectrometry in the screening of beta blockers and their metabolites in human urine. Biological Mass Spectrometry 19:3, pages 137-142.
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J.D. Fitzgerald. 1984. Pharmacology of Antihypertensive Drugs. Pharmacology of Antihypertensive Drugs 249 306 .
H. Weber. (1982) Meeting Requirements for Primate Animals in Drug Development. Journal of Medical Primatology 11:5, pages 263-271.
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L.A. DAMANI & P.A. CROOKS. 1982. Metabolic Basis of Detoxication. Metabolic Basis of Detoxication 69 89 .
V. O. Illi, J. Heindl, J. Balzer & W. Schwartz. (2006) Synthesis of 14 C‐labelled 4‐(2‐hydroxy‐3‐isopropylaminopropoxy)‐2‐methyl‐indole (mapindolol) . Journal of Labelled Compounds and Radiopharmaceuticals 18:5, pages 707-711.
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N. Himori, S. Honma, A. Izumi & T. Ishimori. (1981) Duration and selectivity in ?-adrenoceptor blocking action of a ?-adrenoceptor blocking drug, D-32 in conscious dogs. Naunyn-Schmiedeberg's Archives of Pharmacology 316:1, pages 19-23.
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A. J. Smith & G. T. Tucker. 1981. Adrenergic Activators and Inhibitors. Adrenergic Activators and Inhibitors 417 504 .
M. Guerret, D. Lavene & J.R. Kiechel. (1980) Determination of pindolol in biological fluids by electron-capture GLC. Journal of Pharmaceutical Sciences 69:10, pages 1191-1193.
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Anders Arfwidsson, Göran Hallhagen & Kurt‐Jürgen Hoffmann. (2006) A convenient method for the specific tritium labelling of beta‐adrenoceptor antagonists. Journal of Labelled Compounds and Radiopharmaceuticals 17:3, pages 369-382.
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K. -J. Hoffmann, I. Skånberg & K. O. Borg. (1979) Species differences in the metabolism of pamatolol, a cardioselective beta — adrenoceptor antagonist. European Journal of Drug Metabolism and Pharmacokinetics 4:3, pages 163-173.
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P. Dayer, L. Balant, A. Gorgia, J-L. Eberlin & J. Fabre. (1979) THE DURATION OF ACTION OF PINDOLOL and ITS RELATION TO PLASMA LEVELS. Journal of Clinical Pharmacy and Therapeutics 4:2, pages 87-93.
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Kurt-Jürgen Hoffmann, Anders Arfwidsson, Karl Olof Borg & Inger Skånberg. (1978) Study of the metabolic pathways of alprenolol in man and the dog using stable isotopes. Biological Mass Spectrometry 5:11, pages 634-640.
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R.E. BUCKINGHAM, T.C. HAMILTON & D. ROBSON. (1978) DIMINISHING HYPOTENSIVE EFFECT OF INCREASING DOSES OF PINDOLOL IN DOCA/SALINE HYPERTENSIVE RATS. British Journal of Pharmacology 62:3, pages 362-363.
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R.E. BUCKINGHAMM, C. HAMILTON & D. ROBSON. (2012) STUDIES ON THE CARDIOVASCULAR EFFECTS OF PINDOLOL IN DOCA/SALINE HYPERTENSIVE RATS. British Journal of Pharmacology 60:3, pages 461-469.
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J Meier & E Nuesch. (2012) Pindolol, a beta‐adrenoceptor blocking agent with a negligible first‐ pass effect.. British Journal of Clinical Pharmacology 4:3, pages 371-372.
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W. Riess, S. Brechbühler & W. Theobald. (1976) The Pharmacokinetic Characteristics of Beta-Receptor Antagonists in Man-Similarities and Differences of Clinical Relevance. Australian and New Zealand Journal of Medicine 6, pages 4-13.
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