Citations (82)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (13)
P. J. Simons, I. D. Cockshott, J. B. Glen, E. A. Gordon, S. Knott & R. J. Ruane. (1992) Disposition and pharmacology of propofol glucuronide administered intravenously to animals. Xenobiotica 22:11, pages 1267-1273.
Read now
Read now
P. J. Simons, I. D. Cockshott, E. J. Douglas, E. A. Gordon, S. Knott & R. J. Ruane. (1991) Species differences in blood profiles, metabolism and excretion of 14C-propofol after intravenous dosing to rat, dog and rabbit. Xenobiotica 21:10, pages 1243-1256.
Read now
Read now
J. A. Watt & R. G. Dickinson. (1990) Effects of blockage of urine and/or bile flow on diflunisal conjugation and disposition in rats. Xenobiotica 20:8, pages 835-845.
Read now
Read now
T. A. Sutfin, M. Gabrielsson & C. G. Regårdh. (1987) Effects of biliary excretion on the disposition of felodipine and metabolites in the rat. Xenobiotica 17:10, pages 1203-1214.
Read now
Read now
Harold Boxenbaum. (1983) Evolutionary Biology, Animal Behavior, Fourth-Dimensional Space, and the Raison ďEtre of Drug Metabolism and Pharmacokinetics. Drug Metabolism Reviews 14:5, pages 1057-1097.
Read now
Read now
K. Rozman, K. H. Summer, T. Rozman, H. Greim & Karl K. Rozman. (1982) Elimination of Thioethers Following Administration of Naphthalene and Diethylmaleate to the Rhesus Monkey. Drug and Chemical Toxicology 5:3, pages 265-275.
Read now
Read now
J. K. Chipman, N. A. Bhave, P. C. Hirom & P. Millburn. (1982) Metabolism and excretion of benzo[a]pyrene in the rabbit. Xenobiotica 12:6, pages 397-404.
Read now
Read now
M. E. Davis, W. O. Berndt & H. M. Mehendale. (1980) Alterations of xenobiotic excretory function induced by potassium dichromate or carbon tetrachloride pretreatment. Journal of Toxicology and Environmental Health 6:2, pages 455-465.
Read now
Read now
A. G. M. Willems, H. Overmars, P. Scherpenisse, N. De Lange & L. C. Post. (1980) Diflubenzuron: Intestinal absorption and metabolism in the rat. Xenobiotica 10:2, pages 103-112.
Read now
Read now
J. Jorritsma, J. H. N. Meerman, R. J. Vonk & G. J. Mulder. (1979) Biliary and urinary excretion of drug conjugates: Effect of diuresis and choleresis on excretion of harmol sulphate and harmol glucuronide in the rat. Xenobiotica 9:4, pages 247-252.
Read now
Read now
K.-J. Hoffmann, A. Arfwidsson, K. O. Borg & I. Skånberg. (1979) Identification of Urinary and Biliary Metabolites of Alprenolol in the Rat. Xenobiotica 9:2, pages 93-106.
Read now
Read now
Günther Schmalzing & Ursula Breyer. (1978) Kinetics of [3H] Trifluoperazine in Bile Fistula Rats. Xenobiotica 8:1, pages 45-54.
Read now
Read now
A. M. Guarino, M. O. James & J. R. Bend. (1977) Fate and Distribution of the Herbicides 2,4-Dichloro-phenoxyacetic Acid (2,4-D) and 2,4,5-Trichlorophenoxy-acetic Acid (2,4,5-T) in the Dogfish Shark. Xenobiotica 7:10, pages 623-631.
Read now
Read now
Articles from other publishers (69)
Allan W. Wolkoff. 2011. Comprehensive Physiology. Comprehensive Physiology
1715
1735
.
Alexander V. LyubimovRobert S. Foti, Dan A. Rock, Larry C. Wienkers & Jan L. Wahlstrom. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions
1
68
.
. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety
1
5
.
Sophie L. Regan, James L. Maggs, Thomas G. Hammond, Craig Lambert, Dominic P. Williams & B. Kevin Park. (2010) Acyl glucuronides: the good, the bad and the ugly. Biopharmaceutics & Drug Disposition 31:7, pages 367-395.
Crossref
Crossref
William J. Egan. 2010. Drug Design. Drug Design
165
178
.
B Hagenbuch. (2009) Drug Uptake Systems in Liver and Kidney: A Historic Perspective. Clinical Pharmacology & Therapeutics 87:1, pages 39-47.
Crossref
Crossref
Karl K. Rozman, John Doull & Wayland J. HayesJr.Jr.. 2010. Hayes' Handbook of Pesticide Toxicology. Hayes' Handbook of Pesticide Toxicology
3
101
.
Takashi Nagashima, Takahiko Aoyama, Tsubasa Yokoe, Akiko Fukasawa, Noboru Fukuda, Takahiro Ueno, Hiroshi Sugiyama, Hiroki Nagase & Yoshiaki Matsumoto. (2009) Pharmacokinetic Modeling and Prediction of Plasma Pyrrole-Imidazole Polyamide Concentration in Rats Using Simultaneous Urinary and Biliary Excretion Data. Biological and Pharmaceutical Bulletin 32:5, pages 921-927.
Crossref
Crossref
. (2008) Toxicokinetics of Bisphenol A ‐ Scientific Opinion of the Panel on Food additives, Flavourings, Processing aids and Materials in Contact with Food (AFC). EFSA Journal 6:7.
Crossref
Crossref
William J. Egan. 2007. Annual Reports in Medicinal Chemistry Volume 42. Annual Reports in Medicinal Chemistry Volume 42
449
467
.
Rakesh Dixit. 2007. Veterinary Toxicology. Veterinary Toxicology
25
41
.
Mark J Bailey & Ronald G Dickinson. (2003) Acyl glucuronide reactivity in perspective: biological consequences. Chemico-Biological Interactions 145:2, pages 117-137.
Crossref
Crossref
Sriram Shankar, Ganesan Vaidyanathan, Donna Affleck, Phillip C. Welsh & Michael R. Zalutsky. (2003)
N
-Succinimidyl 3-[
131
I]Iodo-4-phosphonomethylbenzoate ([
131
I]SIPMB), a Negatively Charged Substituent-Bearing Acylation Agent for the Radioiodination of Peptides and mAbs
. Bioconjugate Chemistry 14:2, pages 331-341.
Crossref
Crossref
Maria Shipkova, Victor William Armstrong, Michael Oellerich & Eberhard Wieland. (2003) Acyl Glucuronide Drug Metabolites: Toxicological and Analytical Implications. Therapeutic Drug Monitoring 25:1, pages 1-16.
Crossref
Crossref
Klaas Nico Faber, Michael Müller & Peter L.M Jansen. (2003) Drug transport proteins in the liver. Advanced Drug Delivery Reviews 55:1, pages 107-124.
Crossref
Crossref
Karl K. Rozman, John Doull & Wayland J. HayesJr.Jr.. 2001. Handbook of Pesticide Toxicology. Handbook of Pesticide Toxicology
1
93
.
Min Wang & Ronald G. Dickinson. (1998) Hepatobiliary transport of diflunisal conjugates and taurocholate by the perfused rat liver: The effect of chronic exposure of rats to diflunisal. Life Sciences 62:8, pages 751-762.
Crossref
Crossref
Hisatoshi Shinagawa, Hiroshi Yamaga, Hitoshi Houchigai, Yoshihiro Sumita & Makoto Sunagawa. (1997) Synthesis and biological properties of a new series of anti-MRSA β-lactams; 2-(thiazol-2-ylthio)carbapenems. Bioorganic & Medicinal Chemistry 5:3, pages 601-621.
Crossref
Crossref
Andrew R. King & Ronald G. Dickinson. (1996) The utility of the bile-exteriorized rat as a source of reactive acyl glucuronides: Studies with zomepirac. Journal of Pharmacological and Toxicological Methods 36:3, pages 131-136.
Crossref
Crossref
Mark J. Bailey & Ronald G. Dickinson. (1996) Chemical and Immunochemical Comparison of Protein Adduct Formation of Four Carboxylate Drugs in Rat Liver and Plasma. Chemical Research in Toxicology 9:3, pages 659-666.
Crossref
Crossref
Andrew R. King & Ronald G. Dickinson. (1991) Studies on the reactivity of acyl glucuronides—I. Biochemical Pharmacology 42:12, pages 2289-2299.
Crossref
Crossref
Š. Bezek, V. Ščasnár, M. Kukan & T. Trnovec. (2006) Kinetics of biliary elimination of pentacaine in rats. Biopharmaceutics & Drug Disposition 11:5, pages 403-409.
Crossref
Crossref
T. A. Sutfin, T. Lind, M. Gabrielsson & C. G. Reg»rdh. (1990) Biliary secretion of felodipine metabolites in man after intravenous [14C]felodipine. European Journal of Clinical Pharmacology 38:5, pages 421-424.
Crossref
Crossref
Ch. Fleck & A. Barth. (1990) Influence of xenobiotics on bile flow and bile composition in rats — Methodological approach. Experimental Pathology 39:3-4, pages 175-185.
Crossref
Crossref
K. P. R. Gartland, C. T. Eason, F. W. Bonner & J. K. Nicholson. (1990) Effects of biliary cannulation and buthionine sulphoximine pretreatment on the nephrotoxicity of para-aminophenol in the Fischer 344 rat. Archives of Toxicology 64:1, pages 14-25.
Crossref
Crossref
Wade J. Adams. 1990. Early Phase Drug Evaluation in Man. Early Phase Drug Evaluation in Man
25
38
.
Dirk K. F. Meijer. 2011. Comprehensive Physiology. Comprehensive Physiology
717
758
.
Markku Ylinen, Hannu Hanhijärvi, Jaana Jaakonaho & Pekka Peura. (1989) Stimulation by Oestradiol of the Urinary Excretion of Perfluorooctanoic Acid in the Male rat. Pharmacology & Toxicology 65:4, pages 274-277.
Crossref
Crossref
Ch. Fleck, T. Nguyen Trong & H. Bräunlich. (1989) Relation between renal and hepatic excretion of drugs. Experimental pathology 36:1, pages 43-52.
Crossref
Crossref
Ch. Fleck, S. Richter, G. Tischendorf, W. Klemm & H. Bräunlich. (1989) Relation between renal and hepatic excretion of drugs: XIII. Pharmacokinetics of new antiarrhythmic drug Bonnecor® in rats with normal and impaired excretory functions. Experimental pathology 36:3, pages 165-175.
Crossref
Crossref
ANNIE ARVIDSSON, BARBRO LEIJD, C. E. NORD & B. ANGELIN. (1988) Interindividual variability in biliary excretion of ceftriaxone: effects on biliary lipid metabolism and on intestinal microflora. European Journal of Clinical Investigation 18:3, pages 261-266.
Crossref
Crossref
Karl Rozman. (2016) Disposition of Xenobiotics: Species Differences. Toxicologic Pathology 16:2, pages 123-129.
Crossref
Crossref
Ch. Fleck, Nguyen Trong Thong & H. Bräunlich. (1988) Relation between renal and hepatic excretion of drugs. Experimental pathology 35:2, pages 115-127.
Crossref
Crossref
Ch. Fleck, M. Schultz, D. Seidel & H. Bräunlich. (1988) Relation between renal and hepatic excretion of drugs:. Experimental pathology 34:3, pages 171-180.
Crossref
Crossref
D.J. Maddalena, G.M. Snowdon & J.G. Wilson. (1988) Structure-distribution studies on some 99mTc-o-hydroxybenzyliminodiacetic acid complexes. International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology 15:3, pages 319-325.
Crossref
Crossref
R. K. Verbeeck, R. G. Dickinson & S. M. Pond. (1988) Biliary excretion of diflunisal conjugates in patients with T-tube drainage. European Journal of Clinical Pharmacology 34:4, pages 423-426.
Crossref
Crossref
I Laws & P G Mantle. (1987) Elimination of roquefortine in the rat. Mycotoxin Research 3:1, pages 3-6.
Crossref
Crossref
Ch. Fleck, Ch. Kunze & H. Bräunlich. (1987) Relation between renal and hepatic excretion of drugs. Experimental pathology 32:2, pages 99-110.
Crossref
Crossref
O. Motheová, Š. Bezek, M. Ďurišová, V. Faberová, M. Zemánek, K. Mišánikova & T. Trnovec. (2006) The pharmacokinetics of exaprolol and propranolol in rats with interrupted enterohepatic circulation. Biopharmaceutics & Drug Disposition 7:2, pages 151-162.
Crossref
Crossref
Ch. Fleck & H. Bräunlich. (1986) Relation between renal and hepatic excretion of drugs. Experimental pathology 29:4, pages 235-247.
Crossref
Crossref
C.J. Bowmer & M.S. Yates. (1984) Pharmacokinetics and biliary excretion of bromosulphophthalein, [3H]-ouabain and [3H]-taurocholic acid in rats with glycerol-induced acute renal failure. British Journal of Pharmacology 83:3, pages 773-782.
Crossref
Crossref
Eivor Elovaara, Kerstin Engström & Harri Vainio. (1984) Metabolism and disposition of simultaneously inhaled m-xylene and ethylbenzene in the rat. Toxicology and Applied Pharmacology 75:3, pages 466-478.
Crossref
Crossref
J.J. McDonald, B.M. North, C.R. Breeden, C.-C. Lai & R.W. Roth. (1984) Synthesis and disposition of 14C-labelled gentian violet in F344 rats and B6C3F1 mice. Food and Chemical Toxicology 22:5, pages 331-336.
Crossref
Crossref
O. Tomčíková, Š. Bezek, M. Ďurišová, V. Faberová, M. Zemánek & T. Trnovec. (2006) Biliary excretion and enterohepatic circulation of two beta‐adrenergic blocking drugs, exaprolol and propranolol in rats. Biopharmaceutics & Drug Disposition 5:2, pages 153-162.
Crossref
Crossref
John A. Nash, Laurence J. King, Edward A. Lock & Trevor Green. (1984) The metabolism and disposition of hexachloro-1:3-butadiene in the rat and its relevance to nephrotoxicity. Toxicology and Applied Pharmacology 73:1, pages 124-137.
Crossref
Crossref
Christian Fleck & Helmut Bräunlich. (1984) Methods in testing interrelationships between excretion of drugs via urine and bile. Pharmacology & Therapeutics 25:1, pages 1-22.
Crossref
Crossref
J. L. Barnhart. 1984. Radiocontrast Agents. Radiocontrast Agents
367
418
.
R. J. Allan & T. R. Watson. (1983) The metabolic and pharmacokinetic disposition of mebendazole in the rat. European Journal of Drug Metabolism and Pharmacokinetics 8:4, pages 373-381.
Crossref
Crossref
Lee A. Celio, G. John Digregorio, Eileen Ruch Joseph N. Pace & Anthony J. Piraino. (1983) 5-Fluorouracil Concentrations in Rat Plasma, Parotid Saliva, and Bile and Protein Binding in Rat Plasma. Journal of Pharmaceutical Sciences 72:6, pages 597-599.
Crossref
Crossref
Michele A. Medinsky & John G. Dent. (1983) Biliary excretion and enterohepatic circulation of 2,4-dinitrotoluene metabolites in Fischer-344 rats. Toxicology and Applied Pharmacology 68:3, pages 359-366.
Crossref
Crossref
M Nussbaum, E S Fiala, B Kulkarni, K El-Bayoumy & J H Weisburger. (1983) In vivo metabolism of 3,2'-dimethyl-4-aminobiphenyl (DMAB) bearing on its organotropism in the Syrian golden hamster and the F344 rat.. Environmental Health Perspectives 49, pages 223-231.
Crossref
Crossref
Walter G. Levine. 1983. Biological Basis of Detoxication. Biological Basis of Detoxication
251
285
.
Alan R. Fritzberg & Duane C. Bloedow. 1983. Animal Models in Radiotracer Design. Animal Models in Radiotracer Design
179
209
.
Rolf Gebhardt & Wilhelm Jung. (1982) Biliary secretion of sodium fluorescein in primary monolayer cultures of adult rat hepatocytes and its stimulation by nicotinamide. Journal of Cell Science 56:1, pages 233-244.
Crossref
Crossref
Vernon L. Singleton. 1981.
149
242
.
R. W. Nicholson, K. J. Herman, R. A. Shields & H. J. Testa. (1980) The plasma protein binding of HIDA. European Journal of Nuclear Medicine 5:4, pages 311-312.
Crossref
Crossref
W E Wright & V D Line. (1980) Biliary excretion of cephalosporins in rats: influence of molecular weight. Antimicrobial Agents and Chemotherapy 17:5, pages 842-846.
Crossref
Crossref
Ivor Surveyor, Wye-Poh Fung & Alan J. Jameson. (1980) Prostaglandins and excretion of 99mTc-HIDA in the rat. International Journal of Nuclear Medicine and Biology 7:4, pages 299-303.
Crossref
Crossref
E. Chiotellis & A. Varvarigou. (1980) 99mTc-labelled N-substituted carbamoyl iminodiacetates: Relationship between structure and biodistribution. International Journal of Nuclear Medicine and Biology 7:1, pages 1-7.
Crossref
Crossref
. (1979) Benzoic acid. Food and Cosmetics Toxicology 17, pages 715-722.
Crossref
Crossref
K.H. Summer, K. Rozman, F. Coulston & H. Greim. (1979) Urinary excretion of mercapturic acids in chimpanzees and rats. Toxicology and Applied Pharmacology 50:2, pages 207-212.
Crossref
Crossref
Thomas C. Marshall & H.Wyman Dorough. (1979) Biliary excretion of carbamate insecticides in the rat. Pesticide Biochemistry and Physiology 11:1-3, pages 56-63.
Crossref
Crossref
. (2012) Proceedings of the British Pharmacological Society. British Journal of Pharmacology 64:3.
Crossref
Crossref
Ugo Fonda & Bente Pedersen. (1978) 99mTc-Diethyl-HIDA. European Journal of Nuclear Medicine 3:2, pages 87-89.
Crossref
Crossref
Norbert Kolassa, Elisabeth Tuisl & Otto Kraupp. (1978) Effects of the carboxylesterase inhibitor bis-(p-nitrophenyl)-phosphate on elimination of hexobendine. Biochemical Pharmacology 27:18, pages 2269-2273.
Crossref
Crossref
Nicholas F. Larusso, Donald G. Lindmark & Miklós Müller. (1978) Biliary and renal excretion, hepatic metabolism, and hepatic subcellular distribution of metronidazole in the rat. Biochemical Pharmacology 27:18, pages 2247-2254.
Crossref
Crossref
H. Eckert, J. R. Kiechel, J. Rosenthaler, R. Schmidt & E. Schreier. 1978. Ergot Alkaloids and Related Compounds. Ergot Alkaloids and Related Compounds
719
803
.
D. Lee, Robyn K. Holland & Anne K. Groufsky. (2008) THE EFFECT OF COLLOID CONCENTRATION ON THE FUNCTIONAL CHARACTERISTICS OF ISOLATED PERFUSED RAT LIVER. Australian and New Zealand Journal of Surgery 47:6, pages 822-827.
Crossref
Crossref
Ursula Breyer, Ilse Jahns, Gerhard Irmscher, Hannelore Rassner & Sabine Rehmer. (1977) Kinetics of 35S-perazine in the bile fistula rat. Naunyn-Schmiedeberg's Archives of Pharmacology 300:1, pages 47-56.
Crossref
Crossref