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Xenobiotica
the fate of foreign compounds in biological systems
Volume 6, 1976 - Issue 2
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Original Article

Urinary Excretion of C-Hydroxy Derivatives of Methaqualone in Man

David Burnett Department of Clinical Biochemistry, St. Albans City Hospital, St Albans, Hertfordshire, UK
,
Cedric N. Reynolds School of Natural Sciences, The Hatfield Polytechnic, Hatfield, Hertfordshire, UK
,
Keith Wilson School of Natural Sciences, The Hatfield Polytechnic, Hatfield, Hertfordshire, UK
&
J. Robert Francis Department of Biochemistry, Roche Products Limited, Welwyn Garden City, Hertfordshire, UK
Pages 125-134 | Received 10 Jul 1975, Published online: 30 Sep 2009

Citations (14)

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Andrea Poropatich & Robert Rothchild. (1990) 1H NMR Spectral Simplification with Achiral and Chiral Lanthanide Shift Reagents. 2-Methyl-3-(2′-Hydroxymethylphenyl)-4(3H)-Quinazolinone, A Major Metabolite of Methaqualone. Spectroscopy Letters 23:1, pages 29-43.
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Cedric N. Reynolds, Keith Wilson & David Burnett. (1976) Urinary Excretion of Methaqualone-N-oxide in Man. Xenobiotica 6:2, pages 113-124.
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Articles from other publishers (12)

Donald G. Barceloux. 2012. Medical Toxicology of Drug Abuse. Medical Toxicology of Drug Abuse 504 513 .
Francine Prost & Wolfgang Thormann. (2001) Enantiomeric analysis of the five major monohydroxylated metabolites of methaqualone in human urine by chiral capillary electrophoresis. ELECTROPHORESIS 22:15, pages 3270-3280.
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C. Brenner, R. Hui, J. Passarelli, R. Wu, R. Brenneisen, K. Bracher, M.A. ElSohly, V.D. Ghodoussi & S.J. Salamone. (1996) Comparison of methaqualone excretion patterns using abuscreen ONLINE and EMIT II immunoassays and. Forensic Science International 79:1, pages 31-41.
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S. Goenechea, W. Wessling & K. -J. Goebel. (1983) Studies on the cleavage of glucuronides of some major metabolites of methaqualone with hydrochloric acidUntersuchungen über die Spaltung der Glucuronide einiger bedeutender Methaqualonmetabolite mit Salzsäure. Fresenius' Zeitschrift für analytische Chemie 315:4, pages 359-360.
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M Oram, K Wilson & D Burnett. (2012) The influence of oral contraceptives on the metabolism of methaqualone in man.. British Journal of Clinical Pharmacology 14:3, pages 341-345.
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K Wilson, M Oram, CE Horth & D Burnett. (2012) The influence of the menstrual cycle on the metabolism and clearance of methaqualone.. British Journal of Clinical Pharmacology 14:3, pages 333-339.
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M. Oram, K. Wilson, D. Burnett, S. G. Al-Dabbagh, J. R. Idle & R. L. Smith. (1982) Metabolic oxidation of methaqualone in extensive and poor metabolisers of debrisoquine. European Journal of Clinical Pharmacology 23:2, pages 147-150.
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Keith Wilson, David Burnett, Marcia Oram & Cedric Tabossi Reynolds. (1981) The kinetics of the urinary excretion of the N-oxide and glucuronides of methaqualone in man. European Journal of Drug Metabolism and Pharmacokinetics 6:4, pages 289-295.
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D. Burnett, C. N. Reynolds & K. Wilson. (1979) The metabolism of methaqualone in patients with biliary cirrhosis or secondary carcinoma of the liver. European Journal of Clinical Pharmacology 15:1, pages 57-61.
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G. A. Brine, M. L. Coleman & F. I. Carroll. (2009) Carbon‐13 nuclear magnetic resonance spectra of methaqualone metabolites. Journal of Heterocyclic Chemistry 16:1, pages 25-28.
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K. Wilson, C. N. Reynolds & D. Burnett. (1978) Inter- and intra-individual variation in the metabolism of methaqualone in man after a single oral dose. European Journal of Clinical Pharmacology 13:4, pages 291-297.
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C. N. Reynolds, K. Wilson & D. Burnett. (1978) Metabolism of methaqualone in geriatric patients. European Journal of Clinical Pharmacology 13:4, pages 285-289.
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