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Xenobiotica
the fate of foreign compounds in biological systems
Volume 6, 1976 - Issue 3
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Original Article

Metabolism in Rats and Man of Piromidic Acid, a New Antibacterial Agent

Yutaka Sekine Research and Development Division, Dainippon Pharmaceutical Co., Ltd., 33–94 Enoki-cho, Suita, Osaka, Japan
,
Mie Miyamoto Research and Development Division, Dainippon Pharmaceutical Co., Ltd., 33–94 Enoki-cho, Suita, Osaka, Japan
,
Masahisa Hashimoto Research and Development Division, Dainippon Pharmaceutical Co., Ltd., 33–94 Enoki-cho, Suita, Osaka, Japan
&
Kiyoshi Nakamura Research and Development Division, Dainippon Pharmaceutical Co., Ltd., 33–94 Enoki-cho, Suita, Osaka, Japan
Pages 185-198 | Received 12 May 1975, Published online: 30 Sep 2009

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Read on this site (5)

M. Tanaka, F. Ishikawa & H. Hakusui. (1995) Isolation and identification of seven metabolites of a water-soluble platelet aggregation inhibitor in rat urine. Xenobiotica 25:11, pages 1247-1257.
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Y. Fujimaki, K. Hashimoto, K. Sudo & H. Tachizawa. (1990) Biotransformation of a new pyrrolidinone cognition-enhancing agent: isolation and identification of metabolites in human urine. Xenobiotica 20:10, pages 1081-1094.
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Dennis A. Smith, Kevan Brown & Michael G. Neale. (1985) Chromone-2-Carboxylic Acids: Roles of Acidity and Lipophilicity in Drug Disposition. Drug Metabolism Reviews 16:4, pages 365-388.
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N. Kurobe, S. Nakamura & M. Shimizu. (1980) Metabolites of pipemidic acid in human urine. Xenobiotica 10:1, pages 37-46.
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Jerome Edelson, Clarke Davison & David P. Benziger. (1977) Quinolone and “Azaquinolone” Antimicrobial Agents. Drug Metabolism Reviews 6:1, pages 105-148.
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Articles from other publishers (6)

M. Madhu Sekhar, U. Nagarjuna, V. Padmavathi, A. Padmaja, N. Vasudeva Reddy & T. Vijaya. (2018) Synthesis and antimicrobial activity of pyrimidinyl 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazoles. European Journal of Medicinal Chemistry 145, pages 1-10.
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Toshio Uno, Koji Iuch, Yoshihiro Kawahata & Goro Tsukamoto. (1987) Synthesis of antimicrobial agents. II. Syntheses and antibacterial activities of optically active 7-(3-hydroxypyrrolidin-1-yl)quinolones . Journal of Heterocyclic Chemistry 24:4, pages 1025-1028.
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H. Greg Thomas & Peter C. Ruenitz. (2009) Mechanistic aspects of oxidation of N ‐substituted 5 H ‐dibenz[ c,e ]azepines by aldehyde oxidase . Journal of Heterocyclic Chemistry 21:4, pages 1057-1062.
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H. KATAE, K. KOUNO, Y. SEKINE, M. HASHIMOTO & M. SHIMIZU. (2006) Distribution, excretion and biotransformation of 14 C‐piromidic acid in goldfish Carassius aumtus (L.) . Journal of Fish Diseases 2:6, pages 529-542.
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Hugh M. McIlhenny. 1977. 201 209 .
R. Albrecht. 1977. Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des rechersches pharmaceutiques. Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des rechersches pharmaceutiques 9 104 .

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