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Xenobiotica
the fate of foreign compounds in biological systems
Volume 6, 1976 - Issue 8
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Original Article

Mechanism of 2-Naphthylamine Oxidation Catalysed by Pig Liver Microsomes

Lawrence L. Poulsen Clayton Foundation Biochemical Institute, Dallas, Texas, USA; Department of Chemistry, University of Texas at Austin, Dallas, Texas, USA; Department of Biochemistry, University of Texas Health Science Center (Southwestern Medical School), Dallas, Texas, USA
,
Bettie Sue Siler Masters Clayton Foundation Biochemical Institute, Dallas, Texas, USA; Department of Chemistry, University of Texas at Austin, Dallas, Texas, USA; Department of Biochemistry, University of Texas Health Science Center (Southwestern Medical School), Dallas, Texas, USA
&
Daniel M. Ziegler Clayton Foundation Biochemical Institute, Dallas, Texas, USA; Department of Chemistry, University of Texas at Austin, Dallas, Texas, USA; Department of Biochemistry, University of Texas Health Science Center (Southwestern Medical School), Dallas, Texas, USA
Pages 481-498 | Received 18 Nov 1975, Published online: 30 Sep 2009

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Peter Hlavica & John W. Gorrod. (1982) Biological Oxidation of Nitrogen in Organic Compounds and Disposition of N-Oxidized Product. Critical Reviews in Biochemistry 12:1, pages 39-101.
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Björn Lindeke. (1982) The Non-and Postenzymatic Chemistry of N-Oxygenated Molecules. Drug Metabolism Reviews 13:1, pages 71-121.
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A. Stier, R. Clauss, A. Lücke & I. Reitz. (1980) Redox cycle of stable mixed nitroxides formed from carcinogenic aromatic amines. Xenobiotica 10:7-8, pages 661-673.
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Bernard Testa & Peter Jenner. (1978) Novel Drug Metabolites Produced by Functionalization Reactions: Chemistry and Toxicology. Drug Metabolism Reviews 7:2, pages 325-369.
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Articles from other publishers (17)

Shijiao Huang, Marshall B. Howington, Craig J. Dobry, Charles R. Evans & Scott F. Leiser. (2021) Flavin-Containing Monooxygenases Are Conserved Regulators of Stress Resistance and Metabolism. Frontiers in Cell and Developmental Biology 9.
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P. Hlavica, I. Golly, M. Lehnerer & J. Schulze. (2016) Primary aromatic amines: their N-oxidative bioactivation. Human & Experimental Toxicology 16:8, pages 441-448.
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Terrence J. Monks & Serrine S. Lau. (1988) Reactive intermediates and their toxicological significance. Toxicology 52:1-2, pages 1-53.
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Peter J. Formosa & Tammy M. Bray. (1988) Evidence for metabolism of 3-methylindole by prostaglandin H synthase and mixed-function oxidases in goat lung and liver microsomes. Biochemical Pharmacology 37:22, pages 4359-4366.
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Ronald E. Tynes & Ernest Hodgson. (1985) Catalytic activity and substrate specificity of the flavin-containing monooxygenase in microsomal systems: Characterization of the hepatic, pulmonary and renal enzymes of the mouse, rabbit, and rat. Archives of Biochemistry and Biophysics 240:1, pages 77-93.
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Chikayoshi Nagata, Masahiko Kodama, Teruyuki Kimura & Tsutomu Nakayama. 1985. P-450 and Chemical Carcinogenesis. P-450 and Chemical Carcinogenesis 93 110 .
Peter J. O'Brien. 1984. Free Radicals in Biology. Free Radicals in Biology 289 322 .
Gregory L. Kedderis & Douglas E. Rickert. (1983) Inhibition of the microsomal N-hydroxylation of 2-amino-6-nitrotoluene by a metabolite of methimazole. Biochemical and Biophysical Research Communications 113:2, pages 433-438.
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L.A. DAMANI. 1982. Metabolic Basis of Detoxication. Metabolic Basis of Detoxication 127 149 .
R.W. Estabrook, J. Werringloer, B.S.S. Masters & J.A. Peterson. 1982. Oxidases and Related Redox Systems. Oxidases and Related Redox Systems 811 835 .
R.A. Prough, P.C. Freeman & R.N. Hines. (1981) The oxidation of hydrazine derivatives catalyzed by the purified liver microsomal FAD-containing monooxygenase.. Journal of Biological Chemistry 256:9, pages 4178-4184.
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F.F. Kadlubar, L.E. Unruh, T.J. Flammang, D. Sparks, R.K. Mitchum & G.J. Mulder. (1981) Alteration of urinary levels of the carcinogen, N-hydroxy-2-naphthylamine, and its N-glucuronide in the rat by control of urinary pH, inhibition of metabolic sulfation, and changes in biliary excretion. Chemico-Biological Interactions 33:2-3, pages 129-147.
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R.A. Pelroy & A.J. Gandolfi. (1980) Use of a mixed function amine oxidase for metabolic activation in the ames/salmonella assay system. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 72:2, pages 329-334.
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CHARLES B. KASPER & DONABY HENTON. 1980. Enzymatic Basis of Detoxication. Enzymatic Basis of Detoxication 3 36 .
DANIEL M. ZIEGLER. 1980. Enzymatic Basis of Detoxication. Enzymatic Basis of Detoxication 201 227 .
Bettie Sue Siler Masters. 1978. Biomembranes - Part C: Biological Oxidations. Biomembranes - Part C: Biological Oxidations 240 251 .
Daniel M. Ziegler. 1978. The Molecular Biology of Membranes. The Molecular Biology of Membranes 193 204 .

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