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Xenobiotica
the fate of foreign compounds in biological systems
Volume 6, 1976 - Issue 8
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Original Article

Pharmacokinetics and Metabolism of the New Analgesic Meptazinol in Rats and Patas Monkeys

R. A. Franklin Wyeth Laboratories, Maidenhead, Berks
&
A. Aldridge Wyeth Laboratories, Maidenhead, Berks
Pages 499-508 | Received 13 Nov 1975, Published online: 30 Sep 2009

Citations (11)

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Read on this site (2)

G. R. Murray, G. M. Whiffin, R. A. Franklin & J. A. Henry. (1989) Quantitative Aspects of the Urinary Excretion of Meptazinol and Its Metabolites in Human Volunteers. Xenobiotica 19:6, pages 669-675.
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R. A. Franklin. (1988) The clinical pharxnacokinetics and metabolism of the analgesic meptazinol. Xenobiotica 18:1, pages 105-112.
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Articles from other publishers (9)

R A FranklinD M PierceP G Goode. (1976) On the relation between the analgesic activity of meptazinol and its plasma concentrations in rats, mice and monkeys. Journal of Pharmacy and Pharmacology 28:11, pages 852-853.
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C. Rudolphi & G. Blaschke. (1995) Determination of the stereoselective aspects in in-vitro and in-vivo metabolism of the analgesic meptazinol by high-performance liquid chromatography. Journal of Chromatography B: Biomedical Sciences and Applications 663:2, pages 315-326.
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Harold C. Grice. 1984. Interpretation and Extrapolation of Chemical and Biological Carcinogenicity Data to Establish Human Safety Standards. Interpretation and Extrapolation of Chemical and Biological Carcinogenicity Data to Establish Human Safety Standards 1 152 .
G. Davies, A. J. Sinclair, S. J. Warrington, R. Franklin, T. Frost, A. Latham & P. J. Robson. (1982) Pharmacokinetics of meptazinol in man following repeated intramuscular administration. European Journal of Clinical Pharmacology 23:6, pages 535-538.
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V.J. Stella, S.A. Varia & M. Riedy. (1979) Radiochemical Plasma Salicylamide Assay Using Ring-Labeled Tritiated Salicylamide. Journal of Pharmaceutical Sciences 68:5, pages 648-650.
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R.J. Stephens, J.F. Waterfall & R.A. Franklin. (1978) A review of the biological properties and metabolic disposition of the new analgesic agent, meptazinol. General Pharmacology: The Vascular System 9:2, pages 73-78.
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R.A. FRANKLIN. (2012) THE INFLUENCE OF GASTRIC EMPTYING ON PLASMA CONCENTRATIONS OF THE ANALGESIC, MEPTAZINOL. British Journal of Pharmacology 59:4, pages 565-569.
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RA Franklin, PJ Southgate & AJ Coleman. (2012) Studies on the absorption and disposition of meptazinol following rectal administration.. British Journal of Clinical Pharmacology 4:2, pages 163-167.
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Hugh M. McIlhenny. 1977. 201 209 .

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