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Xenobiotica
the fate of foreign compounds in biological systems
Volume 6, 1976 - Issue 10
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Original Article

Activity of liver microsomal mono-oxygenases on some epoxide-forming tricyclic drugs. I. Kinetics in vitro

J. Pachecka Istituto di Ricerche Farmacologiche ' Mario Negri ', Via Eritrea, 62, 20157, Milan, Italy
,
M. Salmona Istituto di Ricerche Farmacologiche ' Mario Negri ', Via Eritrea, 62, 20157, Milan, Italy
,
L. Cantoni Istituto di Ricerche Farmacologiche ' Mario Negri ', Via Eritrea, 62, 20157, Milan, Italy
,
E. Mussini Istituto di Ricerche Farmacologiche ' Mario Negri ', Via Eritrea, 62, 20157, Milan, Italy
,
C. Pantarotto Istituto di Ricerche Farmacologiche ' Mario Negri ', Via Eritrea, 62, 20157, Milan, Italy
,
A. Frigerio Istituto di Ricerche Farmacologiche ' Mario Negri ', Via Eritrea, 62, 20157, Milan, Italy
&
G. Belvedere Istituto di Ricerche Farmacologiche ' Mario Negri ', Via Eritrea, 62, 20157, Milan, Italy
 show all
Pages 593-598 | Received 25 Jan 1976, Published online: 30 Sep 2009

Citations (11)

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Nevio Cimolai. (2009) Cyclobenzaprine: a new look at an old pharmacological agent. Expert Review of Clinical Pharmacology 2:3, pages 255-263.
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Articles from other publishers (10)

M Salmona, I Conti, R Testa, C Fracasso & S Caccia. (1988) Interaction of the Anticonvulsants, Denzimol and Nafimidone, with Liver Cytochrome P450 in the Rat. Journal of Pharmacy and Pharmacology 40:1, pages 17-21.
Crossref
Meredith L Cotton & G.R. Brian Down. 1988. 41 72 .
C.J. van Boxtel, A. Rane, R.D. Brown & J.T. Wilson. (1981) The formation of carbamazepine epoxide by rat liver microsomes: an investigation of the biphasic kinetic profile. Life Sciences 29:25, pages 2575-2584.
Crossref
Hassan Y. Aboul-Enein & A.A. Al-Badr. 1981. 87 106 .
M M Manson. (1980) Epoxides--is there a human health problem?. Occupational and Environmental Medicine 37:4, pages 317-336.
Crossref
R. Jung, P. Bentley & F. Oesch. (1980) Influence of carbamazepine 10, 11-oxide on drug metabolizing enzymes. Biochemical Pharmacology 29:8, pages 1109-1112.
Crossref
M. H. Bickel. 1980. Psychotropic Agents. Psychotropic Agents 551 572 .
M.S.F. Ross, D.S. Lines, K.R. Brain & R.G. Stevens. (1978) Monooxygenase and epoxide hydratase analysis by high-performance liquid chromatography. Analytical Biochemistry 87:1, pages 267-271.
Crossref
C. Pantarotto, L. Cappellini, A. De Pascale & A. Frigerio. (1977) Epoxide-diol pathway in the metabolism of 5H-dibenzo[b,f]-azepine (iminostilbene). Journal of Chromatography A 134:2, pages 307-314.
Crossref
C. Pantarotto, L. Cappellini, P. Negrini & A. Frigerio. (1977) “Epoxide-diol” metabolic pathway of 5H-dibenzo[a,d]cycloheptene in the rat. Journal of Chromatography A 131, pages 430-436.
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