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Xenobiotica
the fate of foreign compounds in biological systems
Volume 7, 1977 - Issue 8
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Research Article

Circadian Variations in Microsomal Drug-Metabolizing Enzyme Activities in Rat and Rabbit Tissues

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Pages 481-489 | Received 25 Jul 1976, Published online: 22 Sep 2008

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Uğur Hodoglugil, Öznur Ongun, Zafer Güney, Nilgün Allan & Hakan Zengil. (1995) Temporal Variation in Hepatic Superoxide Dismutase Activity in Mice. Chronobiology International 12:2, pages 152-155.
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Laurence S. Kaminsky & Michael J. Fasco. (1992) Small Intestinal Cytochromes P450. Critical Reviews in Toxicology 21:6, pages 407-422.
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RajendraS. Chhabra. (1981) Effect of dietary factors and environmental chemicals on intestinal drug metabolizing enzymes. Toxicological & Environmental Chemistry 3:3-4, pages 173-199.
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J. F. Wheldrake, D. Hawke & R. V. Baudinette. (1979) Mixed-Function Oxidase Activity in a Desert Rodent, Notomys Alexis. Xenobiotica 9:9, pages 565-569.
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Sambamoorthy Bolla, Ramesh R. Boinpally, Srinivasu Poondru, Rambhau Devaraj & Bhaskara R. Jasti. (2013) Pharmacokinetics of Diethylcarbamazine after Single Oral Dose at Two Different Times of Day in Human Subjects. The Journal of Clinical Pharmacology 42:3, pages 327-331.
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Young C Kim & Soo J Lee. (1998) Temporal variation in hepatotoxicity and metabolism of acetaminophen in mice. Toxicology 128:1, pages 53-61.
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. 1994. Neglected Factors in Pharmacology and Neuroscience Research - Biopharmaceutics, Animal characteristics Maintenance, Testing conditions. Neglected Factors in Pharmacology and Neuroscience Research - Biopharmaceutics, Animal characteristics Maintenance, Testing conditions 343 381 .
Amnon Hoffman. (1993) Chronopharmacodynamics of Theophylline Neurotoxicity in Rats. Journal of Pharmaceutical Sciences 82:6, pages 668-669.
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Steven K. Kuwahara & Gilbert J. Mannering. (2009) Effects of Interferon, Polyriboinosinic Acid‐Polyribocytidilic Acid and Steroids on the Cytochrome P450 System of Cultured Primary Mouse Hepatocytes *. Pharmacology & Toxicology 72:4-5, pages 199-204.
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Raghu G. Nath, Suryanarayana V. Vulimiri & Kurt Randerath. (1992) Circadian rhythm of covalent modifications in liver DNA. Biochemical and Biophysical Research Communications 189:1, pages 545-550.
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M. F. Malmary, K. Kabbaj, C. Labat, A. Batalla, I. Houti, S. Moussamih & J. Oustrin. (1992) Chronopharmacokinetics of Cyclosporine A in the Wistar rat following oral administration. European Journal of Drug Metabolism and Pharmacokinetics 17:2, pages 135-144.
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S. Waguri, T. Iyanagi & Y. Uchiyama. (1992) Variations in immunoreactivity for phenobarbital- and 3-methylcholanthrene-inducible cytochromes P-450, and NADPH-cytochrome P-450 reductase in rat liver over twenty-four hours. Histochemistry 97:3, pages 247-253.
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P. M. Bélanger & G. Labrecque. 1992. Biologic Rhythms in Clinical and Laboratory Medicine. Biologic Rhythms in Clinical and Laboratory Medicine 403 409 .
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Christine Beedham, David J. Padwick, Youseff Al-Tayib & John A. Smith. (1989) Diurnal variation and melatonin induction of hepatic molybdenum hydroxylase activity in the guinea-pig. Biochemical Pharmacology 38:9, pages 1459-1464.
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Mitsuru Shimuzu, Shigeru Morita, Tetsuo Yamano & Akio Yamada. (1989) Relationship between hepatic glutathione content and carbon tetrachloride-induced hepatotoxicity in vivo. Toxicology Letters 47:1, pages 95-102.
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Michael Schwenk. (2016) Mucosal Biotransformation. Toxicologic Pathology 16:2, pages 138-146.
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Pierre M. B?langer, Marcel Lalande, Fran?ois Dor?Gaston Labrecque. (1987) Time-dependent variations in the organ extraction ratios of acetaminophen in rat. Journal of Pharmacokinetics and Biopharmaceutics 15:2, pages 133-143.
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Hasan Mukhtar, Benjamin J. DelTitoJr.Jr., Peter M. Matgouranis, Mukul Das, Parathasarathy Asokan & David R. Bickers. (1986) Additive Effects of Ultraviolet B and Crude Coal Tar on Cutaneous Carcinogen Metabolism: Possible Relevance to the Tumorigenicity of the Goeckerman Regimen. Journal of Investigative Dermatology 87:3, pages 348-353.
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Hira L. Gurtoo, Beverly Paigen & Jun Minowada. 1984. Individual Susceptibility to Genotoxic Agents in the Human Population. Individual Susceptibility to Genotoxic Agents in the Human Population 373 415 .
Masahiro Koike, Ryo Norikura, Kenji Mizojiri & Koichi Sugeno. (1984) Time-Dependent Elimination of Cinoxacin in Rats. Journal of Pharmaceutical Sciences 73:12, pages 1697-1700.
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R. Craig Schnell, Haig P. Bozigian, Marc H. Davies, B. Alex Merrick & Kenneth L. Johnson. (1983) Circadian rhythm in acetaminophen toxicity: Role of nonprotein sulfhydryls. Toxicology and Applied Pharmacology 71:3, pages 353-361.
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Peter J. Wedlund & René H. Levy. (1983) Time-Dependent Kinetics VII: Effect of Diurnal Oscillations on the Time Course of Carbamazepine Autoinduction in the Rhesus Monkey. Journal of Pharmaceutical Sciences 72:8, pages 905-909.
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G. Goerz, H. Merk, K. Bolsen, D. Tsambaos & H. Berger. (1983) Influence of chronic UV-light exposure on hepatic and cutaneous monooxygenases. Experientia 39:4, pages 385-386.
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Janet R. Dawson & James W. Bridges. (1981) Intestinal microsomal drug metabolism. Biochemical Pharmacology 30:17, pages 2415-2420.
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B. Bruguerolle, M. Valli, L. Bouyard, G. Jadot & P. Bouyard. (1981) Circadian effect on carbamazepine kinetics in rat. European Journal of Drug Metabolism and Pharmacokinetics 6:3, pages 189-193.
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Roland Grafström & Bo Holmberg. (1980) The effect of long term treatment with disulfiram on content of cytochrome P-450 and on benzo(a)pyrene monooxygenase activity in microsomes isolated from the rat small intestinal mucosa. Toxicology Letters 7:1, pages 79-85.
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Roland Grafstr?m & Frank E. Greene. (1980) Differential effects of disulfiram and diethyldithiocarbamate on small intestinal and liver microsomal benzo[a]pyrene metabolism. Biochemical Pharmacology 29:11, pages 1517-1523.
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Rajendra S. Chhabra. (1979) Intestinal absorption and metabolism of xenobiotics. Environmental Health Perspectives 33, pages 61-69.
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V. Graef & S.W. Golf. (1979) Circadian rhythm of hepatic steroid metabolizing enzyme activities in the rat. Journal of Steroid Biochemistry 11:3, pages 1299-1302.
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RAJENDRA S. CHHABRA & J. MICHAEL TREDGER. 1978. Nutrition and Drug Interrelations. Nutrition and Drug Interrelations 253 277 .

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