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Xenobiotica
the fate of foreign compounds in biological systems
Volume 7, 1977 - Issue 8
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Research Article

Disposition and Metabolic Fate of Tiaramide Hydrochloride, a New Anti-inflammatory Agent, in the Rat

Hideyo Noguchi Research Laboratories, Fujisawa Pharmaceutical Co., Ltd., Kashima, Yodogawa-ku, Osaka, 532, Japan
,
Masao Okui Research Laboratories, Fujisawa Pharmaceutical Co., Ltd., Kashima, Yodogawa-ku, Osaka, 532, Japan
,
Kohsei Noda Research Laboratories, Fujisawa Pharmaceutical Co., Ltd., Kashima, Yodogawa-ku, Osaka, 532, Japan
&
Ryuichi Kato Research Laboratories, Fujisawa Pharmaceutical Co., Ltd., Kashima, Yodogawa-ku, Osaka, 532, Japan
Pages 491-503 | Received 21 Oct 1976, Published online: 22 Sep 2008

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Read on this site (3)

K. Iwasaki, T. Shiraga, K. Noda, K. Tada & H. Noguchi. (1983) Metabolism of tiaramide in vitro III. Sulphoconjugation of alicyclic amine and alcoholic hydroxyl group by hepatic 105 000 g supernatants. Xenobiotica 13:9, pages 565-574.
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H. Noguchi, K. Tada & K. Iwasaki. (1982) Urinary metabolite profile of tiaramide in man and in some animal species. Xenobiotica 12:4, pages 211-220.
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Hideyo Noguchi, Masao Okui, Kohsei Noda, Masahiko Sugiura, Yoshio Tanaka & Ryuichi Kato. (1977) Species Differences in Metabolism of Tiaramide Hydrochloride, a New Anti-inflammatory Agent. Xenobiotica 7:8, pages 505-516.
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Articles from other publishers (5)

Jaeick Lee, Hye Hyun Yoo, Kwang Jin Rhim, Dong-Ryul Sohn & Dong-Hyun Kim. (2007) Metabolism and excretion of 5-ethyl-2-{5-[4-(2-hydroxyethyl)piperazine-1-sulfonyl]-2-propoxyphenyl}-7-propyl-3,5-dihydropyrrolo[3,2-d]-pyrimidin-4-one (SK3530) in rats. Rapid Communications in Mass Spectrometry 21:7, pages 1139-1149.
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Zenzaburo Tozuka, Hayato Kaneko, Toshifumi Shiraga, Yasuyuki Mitani, Manabu Beppu, Shigeyuki Terashita, Akio Kawamura & Akira Kagayama. (2003) Strategy for structural elucidation of drugs and drug metabolites using (MS)n fragmentation in an electrospray ion trap. Journal of Mass Spectrometry 38:8, pages 793-808.
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Zenzaburo Tozuka, Hayato Kaneko, Toshifumi Shiraga, Manabu Beppu, Toshiro Niwa, Akio Kawamura & Akira Kagayama. (2003) New SRM Data Dependent Exclusion (MS)n Measurement for Structural Determination of Drug Metabolites Using LC/ESI/Ion Trap MS. Drug Metabolism and Pharmacokinetics 18:6, pages 390-403.
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Zenzaburo Tozuka, Hayato Kaneko, Toshifumi Shiraga, Yasuyuki Mitani, Akio Kawamura, Akira Kagayama & Anri Aoba. (2002) Strategy for Structure Elucidation of Drug Metabolites Derived from Protonated Molecules and (MS)n Fragmentation of Zotepine, Tiaramide and their Metabolites. Drug Metabolism and Pharmacokinetics 17:4, pages 316-339.
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William J.S. Lockley, Brian Mead, Alan P. Plumb, Dennis A. Smith, Kazuhide Iwasaki, Akira Suzuki, Keitaro Tada & Hideyo Noguchi. (1982) Sex differences in the conjugation of tiaramide by the CR/CD and JCL/SD strains of albino rat. Biochemical Pharmacology 31:14, pages 2433-2435.
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