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Xenobiotica
the fate of foreign compounds in biological systems
Volume 8, 1978 - Issue 8
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Original Article

The Fate of Saccharin Impurities: The Excretion and Metabolism of Toluene-2-sulphonamide in Man and Rat

A. G. Renwick Pharmacology, Faculty of Medicine, University of Southampton, Southampton, UK, SO9 3TU
,
L. M. Ball Department of Biochemistry, St. Mary's Hospital Medical School, London, UK, W2 1PG; Pharmacology Branch, NIEHS, Research Triangle ParkNC, 27709, USA
,
D. L. Corina Department of Physiology and Biochemistry, University of Southampton, Southampton, UK, SO9 3TU
&
R. T. Williams Department of Biochemistry, St. Mary's Hospital Medical School, London, UK, W2 1PG
Pages 461-474 | Received 13 Oct 1977, Published online: 30 Sep 2009

Citations (11)

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Read on this site (5)

H. Kamimura, H. Sasaki & S. Kawamura. (1985) Metabolism of amosulalol hydrochloride in man: Quantitative comparison with laboratory animals. Xenobiotica 15:5, pages 413-420.
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A. G. Renwick, J. L. Pettet, B. Gruchy & D. L. Corina. (1982) The fate of [14C]trithiozine in man. Xenobiotica 12:5, pages 329-343.
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D. M. Gardner & A. G. Renwick. (1978) The Reduction of Nitrobenzoic Acids in the Rat. Xenobiotica 8:11, pages 679-690.
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A. G. Renwick. (1978) The Fate of Saccharin Impurities: The Metabolism and Excretion of 3-Amino [3-14C]benz[d]-isothiazole-1,1-dioxide and 5-Chlorosaccharin in the Rat. Xenobiotica 8:8, pages 487-494.
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A. G. Renwick & R. T. Williams. (1978) The Fate of Saccharin Impurities: The Excretion and Metabolism of [3-14C]Benz[d]-isothiazoline-1,1-dioxide (BIT) in Man and Rat. Xenobiotica 8:8, pages 475-486.
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Articles from other publishers (6)

. 1989. Analytical Artifacts: GC, MS, HPLC, TLC and PC. Analytical Artifacts: GC, MS, HPLC, TLC and PC 753 801 .
A.G. Renwick. 1983. Biological Basis of Detoxication. Biological Basis of Detoxication 151 179 .
Karl Eckhardt, Ming-Tzan King, Elmar Gocke & Dieter Wild. (1980) Mutagenicity study of remsen-fahlberg saccharin and contaminants. Toxicology Letters 7:1, pages 51-60.
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T.W. Sweatman & A.G. Renwick. (1980) The tissue distribution and pharmacokinetics of saccharin in the rat. Toxicology and Applied Pharmacology 55:1, pages 18-31.
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D. Wild, K. Eckhardt, E. Gocke & M. T. King. 1980. Short-Term Test Systems for Detecting Carcinogens. Short-Term Test Systems for Detecting Carcinogens 170 178 .
T. W. Sweatman & A. G. Renwick. (1979) Saccharin Metabolism and Tumorigenicity. Science 205:4410, pages 1019-1020.
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