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Xenobiotica
the fate of foreign compounds in biological systems
Volume 8, 1978 - Issue 12
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Research Article

Increased Aryl Hydrocarbon Hydroxylase Activity in Hepatic Microsomes from Streptozotocin-Diabetic Female Rats

L. A. Reinke Department of Biomedicinal Chemistry, College of Pharmacy, University of Nebraska Medical Center, 42nd and Dewey Avenue, Omaha, Nebraska, 68105, USA
,
S. J. Stohs Department of Biomedicinal Chemistry, College of Pharmacy, University of Nebraska Medical Center, 42nd and Dewey Avenue, Omaha, Nebraska, 68105, USA
&
H. Rosenberg Department of Biomedicinal Chemistry, College of Pharmacy, University of Nebraska Medical Center, 42nd and Dewey Avenue, Omaha, Nebraska, 68105, USA
Pages 769-778 | Received 13 Feb 1978, Published online: 22 Sep 2008

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S. M. Andrews & L. A. Griffiths. (1984) The metabolism and disposition of [2-14C]diazepam in the streptozotocin-diabetic rat. Xenobiotica 14:10, pages 751-760.
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Articles from other publishers (20)

Eero A. Sotaniemi, Olavi Pelkonen, Arno J. Arranto, Päivi Tapanainen, Arja Rautio & Markku Pasanen. (2002) Diabetes and Elimination of Antipyrine in Man: An Analysis of 298 Patients Classified by Type of Diabetes, Age, Sex, Duration of Disease and Liver Involvement*. Pharmacology & Toxicology 90:3, pages 155-160.
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C.R. Barnett, S. Rudd, P.R. Flatt & C. Ioannides. (1993) Sex differences in the diabetes-induced modulation of rat hepatic cytochrome p450 proteins. Biochemical Pharmacology 45:2, pages 313-319.
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M.A. Valentovic, V.J. Teets, D. Nicoll, J. Stern, D. Leppla & G.O. Rankin. (1990) N-(3,5-Dichlorophenyl)succinimide nephrotoxicity in streptozotocin-induced diabetic rats. Toxicology 63:3, pages 327-339.
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M.Helen Grant & Susan J. Duthie. (1988) The cytotoxicity of menadione in hepatocytes isolated from streptozotocin-induced diabetic rats. Biochemical Pharmacology 37:19, pages 3793-3796.
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Zigong Dong, Junyan Hong, Qiang Ma, Dechun Li, John Bullock, Frank J. Gonzalez, Sang S. Park, Harry V. Gelboin & Chung S. Yang. (1988) Mechanism of induction of cytochrome P-450ac (P-450j) in chemically induced and spontaneously diabetic rats. Archives of Biochemistry and Biophysics 263:1, pages 29-35.
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J.B. WatkinsIIIIII & K.M. klueber. (1988) Hepatic phase II biotransformation in C57Bl/KsJ db/db mice: comparison to that in swiss webster and 129 REJ mice. Comparative Biochemistry and Physiology Part C: Comparative Pharmacology 90:2, pages 417-421.
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D. R. Smith, M. R. Rodway, W. A. Haniak & G. D. Bellward. (1987) Hepatic estrogen and androgen receptors and binding proteins in streptozotocin-diabetic male Wistar rats. Diabetologia 30:12, pages 957-962.
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M.Helen Grant & Susan J. Duthie. (1987) Conjugation reactions in hepatocytes isolated from streptozotocin-induced diabetic rats. Biochemical Pharmacology 36:21, pages 3647-3655.
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L V Favreau, D M Malchoff, J E Mole & J B Schenkman. (1987) Responses to insulin by two forms of rat hepatic microsomal cytochrome P-450 that undergo major (RLM6) and minor (RLM5b) elevations in diabetes.. Journal of Biological Chemistry 262:29, pages 14319-14326.
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John B. WatkinsIIIIII & Lori A. Mangels. (1987) Hepatic biotransformation in lean and obese wistar kyoto rats: Comparison to that in streptozotocin-pretreated sprague-dawley rats. Comparative Biochemistry and Physiology Part C: Comparative Pharmacology 88:1, pages 159-164.
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G.C. Farrell. (1987) Drug metabolism in extrahepatic diseases. Pharmacology & Therapeutics 35:3, pages 375-404.
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T. Zysset & L. Sommer. (1986) Diabetes alters drug metabolism-in vivo studies in a streptozotozin-diabetic rat model. Experientia 42:5, pages 560-562.
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Charles Agius & Anthony S. Gidari. (1985) Effect of streptozotocin on the glutathione S-transferases of mouse liver cytosol. Biochemical Pharmacology 34:6, pages 811-819.
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M.Helen morrison & Gabrielle M. Hawksworth. (1984) Glucuronic acid conjugation by hepatic microsomal fractions isolated from streptozotocin-induced diabetic rats. Biochemical Pharmacology 33:23, pages 3833-3838.
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Burkhard Messner, Jaroslava Still & Jürgen Berndt. (1984) Inhibitory effect of cyclic adenosine-3′,5′-monophosphate on the induction of aryl hydrocarbon hydroxylase in the liver of female rats. Pesticide Biochemistry and Physiology 21:2, pages 283-289.
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Milad Bitar & Myron Weiner. (1983) Heme and hemoproteins in streptozotocin-diabetic female rats. Biochemical Pharmacology 32:12, pages 1921-1928.
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Betty L. Warren, Raphael Pak, Malcolm Finlayson, Larry Gontovnick, Geoffrey Sunahara & Gail D. Bellward. (1983) Differential effects of diabetes on microsomal metabolism of various substrates. Biochemical Pharmacology 32:2, pages 327-335.
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Marilyn R. Past & David E. Cook. (1982) Effect of diabetes on rat liver cytochrome P-450. Biochemical Pharmacology 31:20, pages 3329-3334.
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Walid A. Al-Turk, Sidney J. Stohs & Edward B. Roche. (1981) Activities of hepatic and extrahepatic microsomal mixed function oxidase enzymes in diabetic and gonadectomized-diabetic rats. General Pharmacology: The Vascular System 12:5, pages 345-350.
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M. Younes, R. Schlichting & C.-P. Siegers. (1980) Glutathione S-transferase activities in rat liver: Effect of some factors influencing the metabolism of xenobiotics. Pharmacological Research Communications 12:2, pages 115-129.
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