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Xenobiotica
the fate of foreign compounds in biological systems
Volume 8, 1978 - Issue 6
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Research Article

Enzymic Oxidation α to the Acetylenic Group in the Metabolism of N-(5-Pyrrolidinopent-3-ynyl)- Succinimide (BL 14) in vitro

Björn Lindeke Department of Organic Pharmaceutical Chemistry, The Biomedical Center, University of Uppsala, Box 574, Uppsala, S-751 23, Sweden
,
Gösta Hallström Department of Organic Pharmaceutical Chemistry, The Biomedical Center, University of Uppsala, Box 574, Uppsala, S-751 23, Sweden
,
Elisabet Anderson Department of Organic Pharmaceutical Chemistry, The Biomedical Center, University of Uppsala, Box 574, Uppsala, S-751 23, Sweden
&
Bo Karlén Department of Drugs, Division of Pharmacy, National Board of Health and Welfare, Box 607, Uppsala, S-751 25, Sweden
Pages 341-348 | Received 06 May 1977, Published online: 22 Sep 2008

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Read on this site (1)

G. Hallström, B. Lindeke & E. Anderson. (1981) Metabolism of N-(5-pyrrolidinopent-3-ynyl)-succinimide (BL 14) in rat liver preparations. Characterization of four oxidative reactions. Xenobiotica 11:7, pages 459-471.
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Articles from other publishers (5)

Afaf M. Weli & Björn Lindere. (1985) The metabolic fate of pargyline in rat liver microsomes. Biochemical Pharmacology 34:11, pages 1991-1998.
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H. Heusler, J. Epping, S. Heusler, E. Richter, N.P.E. Vermeulen & D.D. Breimer. (1981) Simultaneous determination of blood concentrations of methohexital and its hydroxy metabolite by gas chromatography and identification of 4′-hydroxymethohexital by combined gas—liquid chromatography—mass spectrometry. Journal of Chromatography B: Biomedical Sciences and Applications 226:2, pages 403-412.
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Gösta Hallström & Björn Lindeke. (1981) MetabolicN-oxidation of α-acetylenic amines—A gas chromatographic mass spectrometric investigation of the chemical decomposition ofN-(5-pyrrolidinopent-3-ynyl)succinimideN'-oxide using deuterium substitution. Biological Mass Spectrometry 8:10, pages 514-520.
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Björn Lindeke, Gösta Hallström, Carin Johansson, Örjan Ericsson, Lars-Inge Olsson & Signhild Strömberg. (1981) Metabolism of oxybutynin: Establishment of desethyloxybutynin and oxybutyninN-oxide formation in rat liver preparations using deuterium substitution and gas chromatographic mass spectrometric analysis. Biological Mass Spectrometry 8:10, pages 506-513.
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G. Hallström, B. Lindeke, A.-H. Khuthier & M.A. Al-Iraqi. (1981) Microsomal formation and chemical decomposition of pargyline N-oxide. Chemico-Biological Interactions 34:2, pages 185-200.
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