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Xenobiotica
the fate of foreign compounds in biological systems
Volume 9, 1979 - Issue 3
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Original Article

The effects of cytochrome P-450-448 inhibitors on the binding of benzo(a)pyrene and derivatives to DNA upon microsomal activation

Wan-In Liu Department of Biochemistry, University of Tennessee, Center for the Health Sciences, Memphis, Tennessee, 38163, USA
&
N. H. Sloane Department of Biochemistry, University of Tennessee, Center for the Health Sciences, Memphis, Tennessee, 38163, USA
Pages 165-171 | Received 13 Sep 1978, Published online: 30 Sep 2009

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Read on this site (2)

Ronald A. Martin & F. A. De La Iglesia. (1983) Short-Term Tests with Biochemical End Points Relevant to the Prediction of Carcinogenic Potential of Drugs. Drug Metabolism Reviews 14:3, pages 513-555.
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N. Sloane. (1981) Enzymic hydroxylation of benzo(α)pyrene at the 6-position by vitamin K1-hydroperoxide and rat lung hydroperoxidase. Xenobiotica 11:4, pages 267-274.
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Articles from other publishers (2)

Jamie Horn, James W Flesher & Andreas F Lehner. (2003) The metabolism of formyl-substituted benzanthracenes to hydroxymethyl metabolites in rat liver in vitro and in vivo. Chemico-Biological Interactions 145:1, pages 17-32.
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H.V. Vadi & R.A. Neal. (1981) Microsomal activation of thioacetamide-S-oxide to a metabolite(s) that covalently binds to calf thymus DNA and other polynucleotides. Chemico-Biological Interactions 35:1, pages 25-38.
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