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Xenobiotica
the fate of foreign compounds in biological systems
Volume 9, 1979 - Issue 5
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Original Article

Inhibition of hepatic drug-metabolizing enzymes by arachidonic acid

D. Pessayre Unité de Recherches de Physiopathologie Hépatique (INSERM), Hôpitol Beaujon, 92118, Clichy, France; Departments of Pharmacology and Anesthesiology, The George Washington University Medical Center, Washington, DC, 20037, USA
,
P. Mazel Unité de Recherches de Physiopathologie Hépatique (INSERM), Hôpitol Beaujon, 92118, Clichy, France; Departments of Pharmacology and Anesthesiology, The George Washington University Medical Center, Washington, DC, 20037, USA
,
V. Descatoire Unité de Recherches de Physiopathologie Hépatique (INSERM), Hôpitol Beaujon, 92118, Clichy, France; Departments of Pharmacology and Anesthesiology, The George Washington University Medical Center, Washington, DC, 20037, USA
,
E. Rogier Unité de Recherches de Physiopathologie Hépatique (INSERM), Hôpitol Beaujon, 92118, Clichy, France; Departments of Pharmacology and Anesthesiology, The George Washington University Medical Center, Washington, DC, 20037, USA
,
G. Feldmann Unité de Recherches de Physiopathologie Hépatique (INSERM), Hôpitol Beaujon, 92118, Clichy, France; Departments of Pharmacology and Anesthesiology, The George Washington University Medical Center, Washington, DC, 20037, USA; Laboratoire d'HistoIogie, Embryologie et Cytogenetique, Faculte de Medecine Xavier Bichat, 75018, Paris, France
&
J.-P. Benhamou Unité de Recherches de Physiopathologie Hépatique (INSERM), Hôpitol Beaujon, 92118, Clichy, France; Departments of Pharmacology and Anesthesiology, The George Washington University Medical Center, Washington, DC, 20037, USA
Pages 301-310 | Received 10 Nov 1978, Published online: 30 Sep 2009

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Urs A. Boelsterli, Hyman J. Zimmerman & Anke Kretz-Rommel. (1995) Idiosyncratic Liver Toxicity of Nonsteroidal Antiinflammatory Drugs: Molecular Mechanisms and Pathology. Critical Reviews in Toxicology 25:3, pages 207-235.
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Articles from other publishers (20)

Hermann M. Bolt. 2003. Patty's Toxicology. Patty's Toxicology 1 55 .
Morteza Sarparast, Devon Dattmore, Jamie Alan & Kin Sing Stephen Lee. (2020) Cytochrome P450 Metabolism of Polyunsaturated Fatty Acids and Neurodegeneration. Nutrients 12:11, pages 3523.
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Urs A. Boelsterli. 2013. Drug-Induced Liver Disease. Drug-Induced Liver Disease 343 367 .
Maria Szilagyi. 2003. Patty's Toxicology. Patty's Toxicology 533 588 .
Wolf‐Hagen Schunck & Cosima Schmidt. 2008. Cardiovascular Hormone Systems. Cardiovascular Hormone Systems 333 372 .
Hsien-Tsung Yao, Yi-Wei Chang, Shih-Jung Lan, Chiung-Tong Chen, John T.A. Hsu & Teng-Kuang Yeh. (2006) The inhibitory effect of polyunsaturated fatty acids on human CYP enzymes. Life Sciences 79:26, pages 2432-2440.
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Joseph Prandota. (2004) Possible Pathomechanisms of Sudden Infant Death Syndrome. American Journal of Therapeutics 11:6, pages 517-546.
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Joseph Prandota. (2004) Limitations in the Clinical Usefulness of Single-Dose Pharmacokinetic Studies of Drugs and a Bayesian Approach for the Estimation of Kinetic Parameters. American Journal of Therapeutics 11:4, pages 295-301.
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Jorge H. Capdevila, John R. Falck & Raymond C. Harris. (2000) Cytochrome P450 and arachidonic acid bioactivation: molecular and functional properties of the arachidonate monooxygenase. Journal of Lipid Research 41:2, pages 163-181.
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Steven T. Cragg. 2003. Patty's Toxicology. Patty's Toxicology.
Julia A Hasler, Ronald Estabrook, Michael Murray, Irina Pikuleva, Michael Waterman, Jorge Capdevila, Vijakumar Holla, Christian Helvig, John R Falck, Geoffrey Farrell, Laurence S Kaminsky, Simon D Spivack, Eric Boitier & Philippe Beaune. (1999) Human cytochromes P450. Molecular Aspects of Medicine 20:1-2, pages 1-137.
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Gastons Vereskuns, Clas Wesén, Kerstin Skog & Margaretha Jägerstad. (1998) Inhibitory effect of threo-9,10-dichlorostearic acid on the mutagenic activity of MeIQx, 2-AF and B[a]P in the Ames/Salmonella test. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 416:3, pages 149-157.
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Jorge H. Capdevila, Darryl Zeldin, Armando Karara & John R. Falck. 1996. Physiological Functions of Cytochrome P450 in Relation to Structure and Regulation. Physiological Functions of Cytochrome P450 in Relation to Structure and Regulation 317 339 .
Jorge H. Capdevila, Darryl Zeldin, Keiko Makita, Armando Karara & John R. Falck. 1995. Cytochrome P450. Cytochrome P450 443 471 .
Pradyot K. Mandal, Anupam Bishayee & Malay Chatterjee. (2006) Stimulation of tissue repair by Mikania cordata root extract in carbon tetrachloride‐induced liver injury in mice . Phytotherapy Research 7:1, pages 103-105.
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R. Gasperini, R. Leone, G.P. Velo & M.E. Fracasso. (1990) The inhibition of hepatic microsomal drug metabolism in rats by non-steroidal anti-inflammatory drugs. Pharmacological Research 22, pages 115-116.
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Charles Maponga, Jared C. Barlow & Jerome J. Schentag. (2016) Lack of Effect of Piroxicam on Theophylline Clearance in Healthy Volunteers. DICP 24:2, pages 123-126.
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Gerhard Heinemeyer, Heinz Nau, Alfred G. Hildebrandt & Ivar Roots. (1985) Oxidation and glucuronidation of valproic acid in male rats—Influence of phenobarbital, 3-methylcholanthrene, β-naphthoflavone and clofibrate. Biochemical Pharmacology 34:1, pages 133-139.
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Anne-Marie Taburet & Pierre Aymard. (1983) Valproate glucuronidation by rat liver microsomes. Interaction with parahydroxyphenobarbital. Biochemical Pharmacology 32:24, pages 3859-3861.
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M.Danny Burke, Miriam Falzon & Anthony S. Milton. (1983) Decreased hepatic microsomal cytochrome P450 due to indomethacin: Protective roles of 16,16-dimethylprostaglandin F2α and inducing agents. Biochemical Pharmacology 32:3, pages 389-397.
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