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Xenobiotica
the fate of foreign compounds in biological systems
Volume 9, 1979 - Issue 7
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Original Article

Determination of loxapine in human plasma and urine and identification of three urinary metabolites

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Pages 405-414 | Received 26 Nov 1978, Published online: 30 Sep 2009

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Philippe Nuss, Emmanuelle Corruble, Emmanuelle Baloche, Ricardo P. Garay & Pierre-Michel Llorca. (2022) Fifty years of experience with loxapine for the rapid non-coercive tranquilization of acute behavioral disturbances in schizophrenia patients, and beyond. Expert Review of Neurotherapeutics 22:8, pages 639-653.
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B. Biton, S. Sethuramanujam, Kelly E. Picchione, A. Bhattacharjee, N. Khessibi, F. Chesney, C. Lanneau, O. Curet & P. Avenet. (2012) The Antipsychotic Drug Loxapine Is an Opener of the Sodium-Activated Potassium Channel Slack ( Slo2.2 ) . Journal of Pharmacology and Experimental Therapeutics 340:3, pages 706-715.
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Jiang Ping Luo, Sarvesh C. Vashishtha, Edward M. Hawes, Gordon McKay, Kamal K. Midha & Jim Fang. (2011) In vitro identification of the human cytochrome p450 enzymes involved in the oxidative metabolism of loxapine. Biopharmaceutics & Drug Disposition 32:7, pages 398-407.
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Jennifer SD Zimmer, Shane R Needham, Chad D Christianson, Crystal M Piekarski, Chrystal N Sheaff, Keith Huie, Andrea R Reed & Lori Takahashi. (2010) Validation of HPLC–MS/MS methods for analysis of loxapine, amoxapine, 7-OH-loxapine, 8-OH-loxapine and loxapine N -oxide in human plasma . Bioanalysis 2:12, pages 1989-2000.
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Antonio Párraga, Jörg Holenz & Helmut Buschmann. 2007. Antidepressants, Antipsychotics, Anxiolytics. Antidepressants, Antipsychotics, Anxiolytics 491 616 .
Jan Leo Egge Reubsaet & Stig Pedersen-Bjergaard. (2004) Screening for central nervous system-stimulating drugs in human plasma by liquid chromatography with mass spectrometric detection. Journal of Chromatography A 1031:1-2, pages 203-211.
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Siu Wah Cheung, Siu Wa Tang & Gary Remington. (1991) Simultaneous quantitation of loxapine, amoxapine and their 7- and 8-hydroxy metabolites in plasma by high-performance liquid chromatography. Journal of Chromatography B: Biomedical Sciences and Applications 564:1, pages 213-221.
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Scott M. Johnson, Gloria Nygard & S.K. Wahba Khalil. (1984) Isocratic Liquid Chromatographic Method for the Determination of Amoxapine and its Metabolites. Journal of Pharmaceutical Sciences 73:5, pages 696-699.
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J. Raymond DePauloJr.Jr. & Frank J. AydJr.Jr.. (1982) Loxapine: Fifteen years’ clinical expenence. Psychosomatics 23:3, pages 261-271.
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