Advanced search
Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 9, 1979 - Issue 10
Submit an article Journal homepage
3
Views
18
CrossRef citations to date
0
Altmetric
Research Article

Oxidative Biotransformation of Benzo(a)Pyrene by Human Lung Microsomal Fractions Prepared from Surgical Specimens

Z. Šípal Department of Forensic Medicine, Karolinska Institutet, S-10401, Stockholm, Sweden
,
T. Ahlenius Department of Forensic Medicine, Karolinska Institutet, S-10401, Stockholm, Sweden
,
A. Bergstrand Department of Pathology, Huddinge Hospital, S-10401, Stockholm, Sweden
,
L. Rodriquez Department of Thoracic Surgery, Karolinska Institutet, S-10401, Stockholm, Sweden
&
S. W. Jakobsson Department of Forensic Medicine, Karolinska Institutet, S-10401, Stockholm, Sweden
Pages 633-645 | Received 22 Jan 1979, Published online: 22 Sep 2008

Citations (18)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Herman Autrup. (1982) Carcinogen Metabolism in Human Tissues and Cells. Drug Metabolism Reviews 13:4, pages 603-646.
Read now

Articles from other publishers (17)

Ziru Dai, Guibo Sun, Jiada Yang, Jie Hou, Ping Zhou, Weijie Xie, Guangbo Ge, Xiaobo Sun & Ling Yang. (2019) Interspecies Variation in NCMN-O-Demethylation in Liver Microsomes from Various Species. Molecules 24:15, pages 2765.
Crossref
Joan Albertí, Audrey Martinet, Sònia Sentellas & Miquel Salvà. (2010) Identification of the Human Enzymes Responsible for the Enzymatic Hydrolysis of Aclidinium Bromide. Drug Metabolism and Disposition 38:7, pages 1202-1210.
Crossref
Philip T. Cagle, Jaishree Jagirdar & Helmut H. Popper. 2008. Dail and Hammar’s Pulmonary Pathology. Dail and Hammar’s Pulmonary Pathology 47 157 .
Clyde W. Wheeler & Thomas M. Guenthner. (2006) Cytochrome P‐450‐dependent metabolism of xenobiotics in human lung. Journal of Biochemical Toxicology 6:3, pages 163-169.
Crossref
P.G. Gervasi, V. Longo, F. Naldi, G. Panattoni & F. Ursino. (1991) Xenobiotic-metabolizing enzymes in human respiratory nasal mucgsa. Biochemical Pharmacology 41:2, pages 177-184.
Crossref
Clyde W. Wheeler & Thomas M. Guenthner. (1990) Spectroscopic quantitation of cytochrome P-450 in human lung microsomes. Journal of Biochemical Toxicology 5:4, pages 269-272.
Crossref
Niilo T. Kärki, Risto Pokela, Lauri Nuutinen & Olavi Pelkonen. (2006) Aryl hydrocarbon hydroxylase in lymphocytes and lung tissue from lung cancer patients and controls. International Journal of Cancer 39:5, pages 565-570.
Crossref
Yukio Mori, Hiroshi Yamazaki, Kazumi Toyoshi, Hiroshi Maruyama & Yoichi Konishi. (1986) Activation of carcinogenic N-nitrosopropylamines to mutagens by lung and pancreas S9 fractions from various animal species and man. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 160:3, pages 159-169.
Crossref
Alfred C. Kaelin, Patricia R. Fryer, Helen Grindley & Alan J. Cummings. (1985) A study of the distribution of 7-ethoxycoumarin O-de-ethylase activity in human placental subcellular fractions. Placenta 6:6, pages 481-495.
Crossref
T. E. Gram. 1985. Toxicology of Inhaled Materials. Toxicology of Inhaled Materials 421 470 .
J. Lorenz, H.R. Glatt, R. Fleischmann, R. Ferlinz & F. Oesch. (1984) Drug metabolism in man and its relationship to that in three rodent species: Monooxygenase, epoxide hydrolase, and glutathione S-transferase activities in subcellular fractions of lung and liver. Biochemical Medicine 32:1, pages 43-56.
Crossref
Olavi Pelkonen, Kirsi Vähäkangas, Niilo T. Kärki & Eero A. Sotaniemi. (2016) Genetic and Environmental Regulation of Aryl Hydrocarbon Hydroxylase in Man: Studies with Liver, Lung, Placenta, and Lymphocytes. Toxicologic Pathology 12:3, pages 256-260.
Crossref
Herman Autrup, Roland C. Grafstrom & Curtis C. Harris. 1983. Organ and Species Specificity in Chemical Carcinogenesis. Organ and Species Specificity in Chemical Carcinogenesis 473 495 .
Sten W. Jakobsson, Richard T. Okita, Nell I. Mock, Bettie Sue S. Masters, L. Maximilian Buja & Russell A. Prough. (2009) Monooxygenase Activities of Human Liver, Lung, and Kidney Microsomes – A Study of 42 post mortem Cases . Acta Pharmacologica et Toxicologica 50:5, pages 332-341.
Crossref
Curtis C. Harris, Benjamin F. Trump, Roland Grafstrom & Herman Autrup. (2004) Differences in Metabolism of Chemical Carcinogens in Cultured Human Epithelial Tissues and Cells. Journal of Cellular Biochemistry 18:3, pages 285-294.
Crossref
N. Sabadie, H. B. Richter‐Reichhelm, R. Saracci, U. Mohr & H. Bartsch. (2006) Inter‐individual differences in oxidative benzo( a )pyrene metabolism by normal and tumorous surgical lung specimens from 105 lung cancer patients . International Journal of Cancer 27:4, pages 417-425.
Crossref
Jerome Edelson, David P. Benziger & James E. Peterson. 1981. Annual Reports in Medicinal Chemistry Volume 16. Annual Reports in Medicinal Chemistry Volume 16 319 327 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.