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Xenobiotica
the fate of foreign compounds in biological systems
Volume 9, 1979 - Issue 12
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Research Article

The Induction of Hepatic and Extrahepatic Xenobiotic Metabolism in the Rat and Ferret by a Polychlorinated Biphenyl Mixture (Aroclor 1254)

B. G. Lake The British Industrial Biological Research Association, Woodmansterne Road, Carshalton, Surrey, SM5 4DS, UK
,
M. A. Collins The British Industrial Biological Research Association, Woodmansterne Road, Carshalton, Surrey, SM5 4DS, UK
,
R. A. Harris The British Industrial Biological Research Association, Woodmansterne Road, Carshalton, Surrey, SM5 4DS, UK
&
S. D. Gangolli The British Industrial Biological Research Association, Woodmansterne Road, Carshalton, Surrey, SM5 4DS, UK
Pages 723-731 | Received 14 Feb 1979, Published online: 22 Sep 2008

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Read on this site (2)

Stephen H. Safe. (1994) Polychlorinated Biphenyls (PCBs): Environmental Impact, Biochemical and Toxic Responses, and Implications for Risk Assessment. Critical Reviews in Toxicology 24:2, pages 87-149.
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Stephen Safe & Otto Hutzinger. (1984) Polychlorinated Biphenyls (PCBs) and Polybrominated Biphenyls (PBBs): Biochemistry, Toxicology, and Mechanism of Action. CRC Critical Reviews in Toxicology 13:4, pages 319-395.
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Articles from other publishers (14)

Daniel McLain & Shayne Gad. 2015. Animal Models in Toxicology, Third Edition. Animal Models in Toxicology, Third Edition 499 565 .
Pontus K.A. Forsell, Anders O. Olsson, Erik Andersson, Laxman Nallan & Michael H. Gelb. (2005) Polychlorinated biphenyls induce arachidonic acid release in human platelets in a tamoxifen sensitive manner via activation of group IVA cytosolic phospholipase A2-?. Biochemical Pharmacology 71:1-2, pages 144-155.
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Yasuhiro Kimura, Yasuo Nagata & Randal K. Buddington. (2004) Some Dietary Fibers Increase Elimination of Orally Administered Polychlorinated Biphenyls but Not That of Retinol in Mice. The Journal of Nutrition 134:1, pages 135-142.
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M. H. Court. (2002) Acetaminophen UDP‐glucuronosyltransferase in ferrets: species and gender differences, and sequence analysis of ferret UGT1A6. Journal of Veterinary Pharmacology and Therapeutics 24:6, pages 415-422.
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Shayne C. Gad. (2016) Pigs and Ferrets as Models in Toxicology and Biological Safety Assessment. International Journal of Toxicology 19:3, pages 149-168.
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Nobuyuki Ohgiya, Hiroshi Yokota, Mitsuru Takahashi, Satoru Komoro & Akira Yuasa. (1996) Purification and properties of a new ?-naphthoflavone inducible cytochrome P -450, aryl hydrocarbon hydroxylase from rat kidney. Biochimica et Biophysica Acta (BBA) - General Subjects 1289:1, pages 122-130.
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R.J. Price, A.B. Renwick, J.A. Beamand, F. Esclangon, P.T. Wield, D.G. Walters & B.G. Lake. (1995) Comparison of the metabolism of 7-ethoxycoumarin and coumarin in precision-cut rat liver and lung slices. Food and Chemical Toxicology 33:3, pages 233-237.
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Lisa Beebe, Stephen D. Fox, Charles W. Riggs, Sang S. Park, Harry V. Gelboin, Haleem J. Issaq & Lucy M. Anderson. (1992) Persistent effects of a single dose of Aroclor 1254 on cytochromes P450IA1 and IIB1 in mouse lung. Toxicology and Applied Pharmacology 114:1, pages 16-24.
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Christopher P. Chengelis. (2016) Examples of Alternative Use in Toxicology for Common Species. Journal of the American College of Toxicology 9:3, pages 319-342.
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P G Traber, J Chianale, R Florence, K Kim, E Wojcik & J J Gumucio. (1988) Expression of cytochrome P450b and P450e genes in small intestinal mucosa of rats following treatment with phenobarbital, polyhalogenated biphenyls, and organochlorine pesticides.. Journal of Biological Chemistry 263:19, pages 9449-9455.
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M. A. Hayes. 1987. Polychlorinated Biphenyls (PCBs): Mammalian and Environmental Toxicology. Polychlorinated Biphenyls (PCBs): Mammalian and Environmental Toxicology 77 95 .
Per Ola Darnerud. (2009) Chlorinated Paraffins: Effect of some Microsomal Enzyme Inducers and Inhibitors on the Degradation of 1‐ 14 C‐Chlorododecanes to 14 CO 2 in Mice . Acta Pharmacologica et Toxicologica 55:2, pages 110-115.
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Joshua W. Hamilton & Stephen E. Bloom. (1983) Developmental differences in basal and induced aryl hydrocarbon (benzo[a]pyrene) hydroxylase activity in chick embryo liver and lung in ovo. Biochemical Pharmacology 32:19, pages 2986-2988.
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Lee R. Shull, Michael R. Bleavins, Barbara A. Olson & Richard J. Aulerich. (1982) Polychlorinated biphenyls (Aroclors® 1016 and 1242): Effect on hepatic microsomal mixed function oxidases in mink and ferrets. Archives of Environmental Contamination and Toxicology 11:3, pages 313-321.
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