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Xenobiotica
the fate of foreign compounds in biological systems
Volume 10, 1980 - Issue 1
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Research Article

Metabolism of α- and β-pinene, β-cymene and 1,8-cineole in the brushtail possum, Trichosurus vulpecula

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Pages 17-23 | Received 29 Mar 1979, Published online: 22 Sep 2008

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José Fernando Rinaldi de Alvarenga, Brunna Genaro, Bruna Lamesa Costa, Eduardo Purgatto, Claudine Manach & Jarlei Fiamoncini. (2023) Monoterpenes: current knowledge on food source, metabolism, and health effects. Critical Reviews in Food Science and Nutrition 63:10, pages 1352-1389.
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Lujain Aloum, Mohammad H. Semreen, Taleb H. Al-Tel, Hamza Al-Hroub, Muath Mousa, Richard L. Jayaraj, Eman Alefishat, Abdu Adem & Georg A Petroianu. (2021) Metabolic conversion of β-pinene to β-ionone in rats. Xenobiotica 51:12, pages 1427-1435.
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IanA. Southwell, JosephJ. Brophy & DavidJ. Tucker. (2001) Darwinia citriodora (Myrtaceae), a New Source of Methyl Myrtenate and Methyl Geranate. Journal of Essential Oil Research 13:1, pages 58-60.
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R. Boyle, S. McLean & N. W. Davies. (2000) Biotransformation of 1,8-cineole in the brushtail possum (Trichosurus vulpecula). Xenobiotica 30:9, pages 915-932.
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Stuart McLean & William J. Foley. (1997) Metabolism of Eucalyptus Terpenes by Herbivorous Marsupials. Drug Metabolism Reviews 29:1-2, pages 213-218.
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Y. Asakawa, M. Toyota & T. Ishida. (1988) Biotransformation of 1,4-Cineole, a Monoterpene Ether. Xenobiotica 18:10, pages 1129-1134.
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P. Ventura, M. Schiavi, S. Serafini & A. Selva. (1985) Further studies of trans-sobrerol metabolism: rat, dog and human urine. Xenobiotica 15:4, pages 317-325.
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S. McLean, Heather Galloway, S. Butler, D. Whittle & S. C. Nicol. (1983) Acetylation of sulphanilamide in four marsupials and a monotreme. Xenobiotica 13:2, pages 81-85.
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Wagner B. R. Santos, Lícia T. S. Pina, Marlange A. de Oliveira, Lucas A. B. O. Santos, Marcus V. A. Batista, Gabriela G. G. Trindade, Marcelo C. Duarte, Jackson R. G. S. Almeida, Lucindo J. Quintans-Júnior, Jullyana S. S. Quintans, Mairim R. Serafini, Henrique D. M. Coutinho, Grażyna Kowalska, Tomasz Baj, Radosław Kowalski & Adriana G. Guimarães. (2023) Antinociceptive Effect of a p-Cymene/β-Cyclodextrin Inclusion Complex in a Murine Cancer Pain Model: Characterization Aided through a Docking Study. Molecules 28:11, pages 4465.
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Janah Shaya, Lujain Aloum, Chung-Shin Lu, Peter R. Corridon, Abdulrahman Aoudi, Abeer Shunnar, Eman Alefishat & Georg Petroianu. (2023) Theoretical Study of Hydroxylation of α- and β-Pinene by a Cytochrome P450 Monooxygenase Model. International Journal of Molecular Sciences 24:6, pages 5150.
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Ming-yan Chi, Zu-ying Zhou, Ting Yan, Zi-peng Gong, Yue-ting Li, Si-ying Chen, Yong-lin Wang, Lin Zheng & Yong Huang. (2023) Quantification of six volatile oil constituents of Oleum Cinnamomi in rat plasma and multiple tissues using GC-MS and its application to pharmacokinetic and tissue distribution studies. Journal of Pharmaceutical and Biomedical Analysis 223, pages 115128.
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Rick Wilhiam de Camargo, Marina Goulart da Silva, Guilherme Cabreira Daros, Fabiana Durante de Medeiros, Naiana da Rosa, Caroline Liana Menschhein Medeiros, Eduardo de Medeiros Peretti, Juliete Palandi, Franciane Bobinski, Jucélia Jeremias Fortunato & Rafael Mariano de Bitencourt. (2021) Effects of Chronic Administration of P-Cymene in an Animal Model of LPS-Induced Autism. Planta Medica International Open 8:03, pages e104-e113.
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Bahare Salehi, Shashi Upadhyay, Ilkay Erdogan Orhan, Arun Kumar Jugran, Sumali L.D. Jayaweera, Daniel A. Dias, Farukh Sharopov, Yasaman Taheri, Natália Martins, Navid Baghalpour, William C. Cho & Javad Sharifi-Rad. (2019) Therapeutic Potential of α- and β-Pinene: A Miracle Gift of Nature. Biomolecules 9:11, pages 738.
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Lukas Schmidt & Thomas Göen. (2015) Human metabolism of α-pinene and metabolite kinetics after oral administration. Archives of Toxicology 91:2, pages 677-687.
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Yanqing Gao, Xiangrong Tian, Jian Li, Shibin Shang, Zhanqiang Song & Minggui Shen. (2016) Study on Amphipathic Modification and QSAR of Volatile Turpentine Analogues as Value-Added Botanical Fungicides against Crop-Threatening Pathogenic Fungi. ACS Sustainable Chemistry & Engineering 4:5, pages 2741-2747.
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Yoshiaki Noma & Yoshinori Asakawa. 2015. Handbook of Essential Oils. Handbook of Essential Oils 747 905 .
Lukas Schmidt, Thomas Lahrz, Martin Kraft, Thomas Göen & Hermann Fromme. (2015) Monocyclic and bicyclic monoterpenes in air of German daycare centers and human biomonitoring in visiting children, the LUPE 3 study. Environment International 83, pages 86-93.
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Jian Li, Xiangrong Tian, Yanqing Gao, Shibin Shang, Juntao Feng & Xing Zhang. (2015) A value-added use of volatile turpentine: antifungal activity and QSAR study of β-pinene derivatives against three agricultural fungi. RSC Advances 5:82, pages 66947-66955.
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Michael Murray. 2012. Metabolism of Drugs and Other Xenobiotics. Metabolism of Drugs and Other Xenobiotics 517 542 .
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CLARE MCARTHUR, PRUE E. LONEY, NOEL W. DAVIES & GREGORY J. JORDAN. (2010) Early ontogenetic trajectories vary among defence chemicals in seedlings of a fast‐growing eucalypt. Austral Ecology 35:2, pages 157-166.
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Yoshiaki Noma & Yoshinori Asakawa. 2010. Comprehensive Natural Products II. Comprehensive Natural Products II 669 801 .
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M. De Vincenzi, M. Silano, A. De Vincenzi, F. Maialetti & B. Scazzocchio. (2002) Constituents of aromatic plants: eucalyptol. Fitoterapia 73:3, pages 269-275.
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Kenneth K Chan. (2001) Quantitation of monoterpenoid compounds with potential medicinal use in biological fluids. Journal of Chromatography A 936:1-2, pages 47-57.
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Rebecca Boyle, Stuart McLean, William Foley, Noel W Davies, Evan J Peacock & Ben Moore. (2001) Metabolites of dietary 1,8-cineole in the male koala (Phascolarctos cinereus). Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 129:4, pages 385-395.
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Georgia J Pass, Stuart McLean & Ieva Stupans. (1999) Induction of xenobiotic metabolising enzymes in the common brushtail possum, Trichosurus vulpecula, by Eucalyptus terpenes. Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology 124:3, pages 239-246.
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R.M Bolton & J.T Ahokas. (1997) Purification and Characterisation of Hepatic Glutathione Transferases from a Herbivorous Marsupial, the Brushtail Possum (Trichosurus vulpecula). Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology 116:4, pages 467-475.
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Ian A. Southwell, Craig D. A. Maddox & Myron P. Zalucki. (1995) Metabolism of 1,8-cineole in tea tree (Melaleuca alternifolia andM. linariifolia) by pyrgo beetle (Paropsisterna tigrina). Journal of Chemical Ecology 21:4, pages 439-453.
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Stuart McLean, William J. Foley, Noel W. Davies, Susan Brandon, Li Duo & Adrian J. Blackman. (1993) Metabolic fate of dietary terpenes fromEucalyptus radiata in common ringtail possum (Pseudocheirus peregrinus). Journal of Chemical Ecology 19:8, pages 1625-1643.
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W. J. Foley, E. V. Lassak & J. Brophy. (1987) Digestion and absorption ofEucalyptus essential oils in greater glider (Petauroide svolans) and brushtail possum (Trichosurus vulpecula). Journal of Chemical Ecology 13:11, pages 2115-2130.
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T. Ishidax, Y. Asakawa, T. Takemoto & T. Aratani. (1981) Terpenoids Biotransformation in Mammals III: Biotransformation of α-Pinene, β-Pinene, Pinane, 3-Carene, Carane, Myrcene, and p-Cymene in Rabbits. Journal of Pharmaceutical Sciences 70:4, pages 406-415.
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