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Xenobiotica
the fate of foreign compounds in biological systems
Volume 10, 1980 - Issue 2
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Research Article

Enzymic and electrophoretic characterization of the hexachlorobenzene-induced cytochrome P-450 in the liver of rat

W. Vizethum Department of Dermatology, University of Düsseldorf, Moorenstr. 5, 4000, Düsseldorf, FR, Germany
,
F. Burkhardt Department of Dermatology, University of Düsseldorf, Moorenstr. 5, 4000, Düsseldorf, FR, Germany
&
G. Goerz Department of Dermatology, University of Düsseldorf, Moorenstr. 5, 4000, Düsseldorf, FR, Germany
Pages 145-150 | Received 28 May 1979, Published online: 22 Sep 2008

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HillaryM. Carpenter, DavidE. Williams & DonaldR. Buhler. (1985) A comparison of the effects of hexachlorobenzene, β‐naphthoflavone, and phenobarbital on cytochrome p‐450 and mixed‐function oxidases in Japanese quail. Journal of Toxicology and Environmental Health 15:1, pages 93-108.
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RonaldB. Franklin, RobertK. Breger & JohnJ. Lech. (1983) Comparative effects of hexachloro‐and hexabromobenzene on hepatic monooxygenase activity of male and female rats. Journal of Toxicology and Environmental Health 12:2-3, pages 223-234.
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Articles from other publishers (12)

Ben van Ommen & Peter J. van Bladeren. (1989) POSSIBLE REACTIVE INTERMEDIATES IN THE OXIDATIVE BIOTRANSFORMATION OF HEXACHLOROBENZENE. Drug Metabolism and Drug Interactions 7:2-3.
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G. Goerz & R. Lissner. 1988. Neue Entwicklungen in der Dermatologie. Neue Entwicklungen in der Dermatologie 157 176 .
Rolf Teschke, Kai Könemann, Klaus Bolsen & Günter Goerz. (1986) Effect of alcohol and hexachlorobenzene administration on hepatic alcohol and xenobiotic metabolizing enzymes. Biochemical Pharmacology 35:16, pages 2827-2832.
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Patricia Linko, Heather N. Yeowell, Thomas A. Gasiewicz & Joyce A. Goldstein. (2006) Induction of cytochrome P‐450 isozymes by hexachlorobenzene in rats and aromatic hydrocarbon (Ah)—Responsive mice. Journal of Biochemical Toxicology 1:2, pages 95-107.
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Nadezhda I. Gutkina & Vladimir M. Mishin. (1986) Immunochemical evidences that hexachlorobenzene induces two forms of cytochrome p-450 in the rat liver microsomes. Chemico-Biological Interactions 58, pages 57-68.
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Mark E. Hahn, Thomas A. Gasiewicz, Joyce A. Goldstein & Patricia Linko. (1986) Effect of hexachlorobenzene on the specific binding of 2,3,7,8,-TCDD to the hepatic receptor. Chemosphere 15:9-12, pages 1691-1698.
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B. van Ommen, P.J. van Bladeren, J.H.M. Temmink & F. Müller. (1985) Formation of pentachlorophenol as the major product of microsomal oxidation of hexachlorobenzene. Biochemical and Biophysical Research Communications 126:1, pages 25-32.
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G. Goerz, K. Bolsen & H. Merk. (1985) Influence of chloroquine on the porphyrin metabolism. Archives of Dermatological Research 277:2, pages 114-117.
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Rolf Teschke, Klaus Bolsen, Helga Landmann & Günter Goerz. (1983) Effect of hexachlorobenzene on the activities of hepatic alcohol metabolizing enzymes. Biochemical Pharmacology 32:11, pages 1745-1751.
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J.A. Goldstein, P. Linko, J.N. Huckins & D.L. Stalling. (1982) Structure-activity relationships of chlorinated benzenes as inducers of different forms of cytochrome P-450 in rat liver. Chemico-Biological Interactions 41:2, pages 131-139.
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Jørn A. Holme & Erik Dybing. (1982) Induction of liver microsomal cytochrome P-450 And associated monooxygenases by octachlorostyrene in inbred strains of mice. Biochemical Pharmacology 31:15, pages 2523-2529.
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Jørn A. Holme & Erik Dybing. (2009) Induction of Liver Microsomal Cytochrome P‐450 and Associated Monooxygenases by Octachlorostyrene in the Rat. Acta Pharmacologica et Toxicologica 50:1, pages 41-49.
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