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Xenobiotica
the fate of foreign compounds in biological systems
Volume 10, 1980 - Issue 3
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Research Article

Metabolism of clebopride in vitro. Mass spectrometry and identification of products of amide hydrolysis and N-debenzylation

G. Huizing Department of Pharmacy, Chelsea College, University of London, Manresa Road, London, SW3 6LX, UK; Laboratory of Clinical Pharmacy and Toxicology, Central Hospital Pharmacy for The Hague, PO Box 43100, 2504 AC, The Hague, The Netherlands
,
A. H. Beckett Department of Pharmacy, Chelsea College, University of London, Manresa Road, London, SW3 6LX, UK
,
J. Segura Division of Biochemistry and Biopharmaceutics, Institute of Research, Laboratories Almirall, SA, Barcelona, 24, Spain
&
O. M. Bakke Division of Biochemistry and Biopharmaceutics, Institute of Research, Laboratories Almirall, SA, Barcelona, 24, Spain; Laboratory of Clinical Biochemistry, 5016 Haukeland Sykehus, Bergen, Norway
Pages 211-218 | Received 03 May 1979, Published online: 22 Sep 2008

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G. Huizing & A. H. Beckett. (1980) Metabolism of clebopride in vitro Identification of N-oxidized products. Xenobiotica 10:7-8, pages 593-602.
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Articles from other publishers (6)

Lishan Lin. 2014. Handbook of Metabolic Pathways of Xenobiotics. Handbook of Metabolic Pathways of Xenobiotics 1 3 .
Hao Sun & Dennis O. Scott. (2011) Metabolism of 4-Aminopiperidine Drugs by Cytochrome P450s: Molecular and Quantum Mechanical Insights into Drug Design. ACS Medicinal Chemistry Letters 2:8, pages 638-643.
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J SEGURA, I GARCÍA, L BORJA, E TARRÚS & O M BAKKE. (1981) The pharmacokinetics of a new benzamide drug, clebopride, in the rat and the dog. Journal of Pharmacy and Pharmacology 33:1, pages 214-218.
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Gerard Huizing, Jordi Segura & Arnold H Beckett. (1980) On the mechanism of metabolic N-dealkylation. Isolation of a relatively stable carbinolamine. Journal of Pharmacy and Pharmacology 32:1, pages 650-651.
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Janine Rose & Neal CastagnoliJr.Jr.. (2006) The metabolism of tertiary amines. Medicinal Research Reviews 3:1, pages 73-88.
Crossref
Jerome Edelson, David P. Benziger & James E. Peterson. 1981. Annual Reports in Medicinal Chemistry Volume 16. Annual Reports in Medicinal Chemistry Volume 16 319 327 .

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