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Xenobiotica
the fate of foreign compounds in biological systems
Volume 10, 1980 - Issue 7-8
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Research Article

Biotransformation of nitrosobenzene, phenylhydroxylamine, and aniline in the isolated perfused rat liver

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Pages 499-516 | Received 29 Oct 1979, Published online: 22 Sep 2008

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Hong Song, Calvin A. Lang & Theresa S. Chen. (1999) The Role of Glutathione INp-Aminophenol-Induced Nephrotoxicity in the Mouse. Drug and Chemical Toxicology 22:3, pages 529-544.
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J. M. Dady, S. P. Bradbury, A. D. Hoffman, M. M. Voit & D. L. Olson. (1991) Hepatic microsomal N-hydroxylation of aniline and 4-chloroaniline by rainbow trout (Onchorhyncus mykiss). Xenobiotica 21:12, pages 1605-1620.
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J. Vervoort, P. A. De Jager, J. Steenbergen & I. M. C. M. Rietjens. (1990) Development of a 19F-n.m.r. method for studies on the in vivo and in vitro metabolism of 2-fluoroaniline. Xenobiotica 20:7, pages 657-670.
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C. T. A. Evelo, J. F. M. Versteegh & B. J. Blaauboer. (1984) Kinetics of the formation and secretion of the aniline metabolite 4-aminophenol and its conjugates by isolated rat hepatocytes. Xenobiotica 14:5, pages 409-416.
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B. J. Blaauboer & C. W. M. Van Holsteijn. (1983) Formation and disposition of N-hydroxylated metabolites of aniline and nitrobenzene by isolated rat hepatocytes. Xenobiotica 13:5, pages 295-302.
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Robert O. Beauchamp, Richard D. Irons, Douglas E. Rickert, D. Bruce Couch, Thomas E. Hamm & J. P. Lyon. (1982) A Critical Review of the Literature on Nitrobenzene Toxicity. CRC Critical Reviews in Toxicology 11:1, pages 33-84.
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Articles from other publishers (23)

Hrvoj VančikHrvoj Vančik. 2013. Aromatic C-nitroso Compounds. Aromatic C-nitroso Compounds 141 150 .
Weiyuan Chang, Shrish Barve & Theresa S. Chen. (2012) p-Aminophenol-induced cytotoxicity in Jurkat T Cells: Protective effect of 2(RS)-n-propylthiazolidine-4(R)-carboxylic acid. Journal of Biochemical and Molecular Toxicology 26:2, pages 71-78.
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Zvi RappoportP. Eyer & D. Gallemann. 2010. Patai's Chemistry of Functional Groups. Patai's Chemistry of Functional Groups.
Harpal Singh, Elissa Purnell & Carion Smith. (2007) Mechanistic Study on Aniline-Induced Erythrocyte Toxicity. Archives of Industrial Hygiene and Toxicology 58:3, pages 275-285.
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Daniel M. Copeland, Ann H. West & George B. Richter-Addo. (2003) Crystal structures of ferrous horse heart myoglobin complexed with nitric oxide and nitrosoethane. Proteins: Structure, Function, and Genetics 53:2, pages 182-192.
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Donna L Savigni, Dieter Wege, Garth S Cliff, Mark L.H Meesters & Evan H Morgan. (2003) Iron and transition metal transport into erythrocytes mediated by nifedipine degradation products and related compounds. Biochemical Pharmacology 65:8, pages 1215-1226.
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J.P Cravedi, G Boudry, M Baradat, D Rao & L Debrauwer. (2001) Metabolic fate of 2,4-dichloroaniline, prochloraz and nonylphenol diethoxylate in rainbow trout: a comparative in vivo/in vitro approach. Aquatic Toxicology 53:3-4, pages 159-172.
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Monica Valentovic, John G Ball, Syam Stoll & G.O Rankin. (2001) 3,4-Dichlorophenylhydroxylamine cytotoxicity in renal cortical slices from Fischer 344 rats. Toxicology 162:3, pages 149-156.
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Brian L. Goodwin, Colin R.J. Ruthven & Merton Sandler. (1997) Metabolism of phenylethanolamines and 2-oxo-2-phenylethylamines in the rat. General Pharmacology: The Vascular System 28:4, pages 535-543.
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Hirotada Fujii, Baolu Zhao, Janusz Koscielniak & Lawrence J. Berliner. (2005) In vivo EPR studies of the metabolic fate of nitrosobenzene in the mouse . Magnetic Resonance in Medicine 31:1, pages 77-80.
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Lynn M. Fowler, John R. Foster & Edward A. Lock. (1993) Effect of ascorbic acid, acivicin and probenecid on the nephrotoxicity of 4-aminophenol in the Fischer 344 rat. Archives of Toxicology 67:9, pages 613-621.
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M. Duverger-van Bogaert, D. Wiame & C. Stecca. (1992) Oxidative activation of 2-aminofluorene by human red blood cell cytosol. Biochemical Pharmacology 44:12, pages 2422-2424.
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Lynn M. Fowler, Richard B. Moore, John R. Foster & Edward A. Lock. (2016) Nephrotoxicity of 4-Aminophenol Glutathione Conjugate. Human & Experimental Toxicology 10:6, pages 451-459.
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J.S. Bus & J.A. Popp. (1987) Perspectives on the mechanism of action of the splenic toxicity of aniline and structurally-related compounds. Food and Chemical Toxicology 25:8, pages 619-626.
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Dominique Larrey, Marina Tinel, Philippe Letteron, Jean Geneve, Veronique Descatoire & Dominique Pessayre. (1986) Formation of an inactive cytochrome P-450Fe(II)-metabolite complex after administration of amiodarone in rats, mice and hamsters. Biochemical Pharmacology 35:13, pages 2213-2220.
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Peter Eyer & Dušan Podhradský. (1986) Evaluation of the micromethod for determination of glutathione using enzymatic cycling and Ellman's reagent. Analytical Biochemistry 153:1, pages 57-66.
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M. Ascherl, P. Eyer & H. Kampffmeyer. (1985) Formation and disposition of nitrosochloramphenicol in rat liver. Biochemical Pharmacology 34:20, pages 3755-3763.
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P. Eyer, E. Lierheimer & M. Schneller. (1984) Reactions of nitrosochloramphenicol in blood. Biochemical Pharmacology 33:14, pages 2299-2308.
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James L. Wilmer, Gregory L. Erexson & Andrew D. Kligerman. 1984. Sister Chromatid Exchanges. Sister Chromatid Exchanges 561 567 .
P. Eyer & M. Schneller. (1983) Reactions of the nitroso analogue of chloramphenicol with reduced glutathione. Biochemical Pharmacology 32:6, pages 1029-1036.
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P. Eyer & H. Kampffmeyer. (1982) Inhibition of glutathione excretion, bile flow, and alterations of the glutathione status by 4-nitrosophenetol during perfusion of rat livers. Chemico-Biological Interactions 42:2, pages 209-223.
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G.J. Mulder, L.E. Unruh, F.E. Evans, B. Ketterer & F.F. Kadlubar. (1982) Formation and identification of glutathione conjugates from 2-nitrosofluorene and N-hydroxy-2-aminofluorene. Chemico-Biological Interactions 39:1, pages 111-127.
Crossref
Werner Lenk & Heidrun Sterzl. (1982) DIFFERENCES IN THE FERRIHEMOGLOBINFORMING CAPABILITIES AND CARCINOGENICITIES BETWEEN MONOCYCLIC AND POLYCYCLIC N-ACYLARYLAMINES AND THEIR DERIVATIVES. Drug Metabolism and Drug Interactions 4:2-3.
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