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Xenobiotica
the fate of foreign compounds in biological systems
Volume 10, 1980 - Issue 7-8
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Research Article

Effects and metabolic pathway of 4-dimethylaminophenol during kidney perfusion

R. Elbers Pharmakologisches Institut, der Universität München, Nußbaumstrasse 26, D-8000, München, FR, Germany
,
H. G. Kampffmeyer Pharmakologisches Institut, der Universität München, Nußbaumstrasse 26, D-8000, München, FR, Germany
&
H. Rabes Pathologisches Institut, der Universität München, Nußbaumstrasse 26, D-8000, München, FR, Germany
Pages 621-632 | Received 22 Nov 1979, Published online: 22 Sep 2008

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K. G. Eckert, P. Eyer, J. Sonnenbichler & I. Zetl. (1990) Activation and detoxication of aminophenols. II. Synthesis and structural elucidation of various thiol addition products of 1,4-benzoquinoneimine and N-acetyl-1,4-benzoquinoneimine. Xenobiotica 20:4, pages 333-350.
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H. Behrendt & H. G. Kampffmeyer. (1989) Absorption and ester cleavage of methyl salicylate by skin of single-pass perfused rabbit ears. Xenobiotica 19:2, pages 131-141.
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Peter H. Bach & Enoch N. Kwizera. (1988) Nephrotoxicity: A rational approach to target cell injury in vitro in the kidney. Xenobiotica 18:6, pages 685-698.
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J. Stewart & J. P. McCrary. (1987) Comparison of the glucuronidation ability of liver microsomes from rats treated with 3-methylcholanthrene or phenolic antioxidants. Xenobiotica 17:9, pages 1039-1046.
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Peter H. Bach, James W. Bridges & Gilbert H. Mudge. (1985) Chemically Induced Renal Papillary Necrosis and Upper Urothelial Carcinoma. Part 1. CRC Critical Reviews in Toxicology 15:3, pages 217-329.
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Peter H. Bach, James W. Bridges & Gilbert H. Mudge. (1985) Chemically Induced Renal Papillary Necrosis and Upper Urothelial Carcinoma. Part 2. CRC Critical Reviews in Toxicology 15:4, pages 331-439.
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L. L. Szinicz & N. Weger. (1980) Effects of 4-dimethylaminophenol in rat kidneys, isolated rat kidney tubules and hepatocytes. Xenobiotica 10:7-8, pages 611-620.
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Articles from other publishers (11)

Thomas Zilker & Peter Eyer. 2017. Critical Care Toxicology. Critical Care Toxicology 2779 2789 .
Thomas Zilker & Peter Eyer. 2016. Critical Care Toxicology. Critical Care Toxicology 1 12 .
Kian Hong Ng, Beng Gek Lim & Kim Ping Wong. (2003) Sulfate conjugating and transport functions of MDCK distal tubular cells. Kidney International 63:3, pages 976-986.
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Claudia Kohlert, Gernot Schindler, Reinhard W März, Gudrun Abel, Benno Brinkhaus, Hartmut Derendorf, Eva‐Ulrike Gräfe & Markus Veit. (2013) Systemic Availability and Pharmacokinetics of Thymol in Humans. The Journal of Clinical Pharmacology 42:7, pages 731-737.
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Klaus-Gustav Eckert, Folke R. Elbers & Peter Eyer. (1989) Depletion of mitochondrial coenzyme A and glutathione by 4-dimethylaminophenol and formation of mixed thioethers. Biochemical Pharmacology 38:19, pages 3253-3259.
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D. Schrenk, W. Dekant, P.H. Wünsch & D. Henschler. (1988) Role of metabolic activation in the toxicity of S-(pentachlorobutadienyl)glutathione and in the isolated perfused rat kidney. Toxicology in Vitro 2:4, pages 283-290.
Crossref
T.C. Marrs, J. Scawin & D.W. Swanston. (1984) The acute intravenous and oral toxicity in mice, rats and guinea-pigs of 4-dimethylaminophenol (DMAP) and its effects on haematological variables. Toxicology 31:2, pages 165-173.
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P. Eyer & E. Lengfelder. (1984) Radical formation during autoxidation of 4-dimethylaminophenol and some properties of the reaction products. Biochemical Pharmacology 33:7, pages 1005-1013.
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Jelka Tomašić. 1983. Drug Metabolite Isolation and Determination. Drug Metabolite Isolation and Determination 149 160 .
Henk Koster, Ina Halsema, Egbert Scholtens, K.Sandy Pang & Gerard J. Mulder. (1982) Kinetics of sulfation and glucuronidation of harmol in the perfused rat liver preparation. Biochemical Pharmacology 31:19, pages 3023-3028.
Crossref
R. Elbers, P. Eyer, H. Kampffmeyer & S. Soboll. 1982. Biological Reactive Intermediates—II. Biological Reactive Intermediates—II 419 429 .

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