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Xenobiotica
the fate of foreign compounds in biological systems
Volume 10, 1980 - Issue 7-8
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Research Article

The origin of 1-(3-pyridyl-N-oxide)ethanol as a metabolite of 3-acetylpyridine

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Pages 645-653 | Received 31 Jan 1980, Published online: 22 Sep 2008

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Yasushi Yamazoe, Kazumi Ito & Kouichi Yoshinari. (2011) Construction of a CYP2E1-template system for prediction of the metabolism on both site and preference order. Drug Metabolism Reviews 43:4, pages 409-439.
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J. W. Gorrod & N. J. Gooderham. (1985) Microsomal N- and C-oxidation of 4-substituted N-benzylanilines. Xenobiotica 15:12, pages 1021-1031.
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P. Eyer & W. Hell. (1983) The metabolism of 3-benzoylpyridine. Xenobiotica 13:11, pages 649-659.
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. (2013) Scientific opinion on Flavouring Group Evaluation 24, Revision 2 (FGE.24Rev2): Pyridine, pyrrole, indole and quinoline derivatives from chemical group 28. EFSA Journal 11:11.
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. (2011) Scientific Opinion on Flavouring Group Evaluation 17, Revision 3 (FGE.17Rev3): Pyrazine derivatives from chemical group 24. EFSA Journal 9:11.
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. (2011) Scientific Opinion on Flavouring Group Evaluation 17, Revision 2 (FGE.17Rev2): Pyrazine derivatives from chemical group 24. EFSA Journal 9:5.
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PETER A CROOKS, LYAQUATALI A DAMANI & DAVID A COWAN. (1981) Synthesis of N -oxide derivatives of metyrapone and their detection as in vitro metabolites . Journal of Pharmacy and Pharmacology 33:1, pages 309-312.
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. (2008) Flavouring Group Evaluation 17, Revision 1 (FGE.17Rev1): Pyrazine derivatives from chemical group 24 - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC). EFSA Journal 6:9, pages 812.
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. (2008) Pyridine, pyrrole, indole and quinoline derivatives from chemical group 28 Flavouring Group Evaluation 24, Revision 1 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC). EFSA Journal 6:8, pages 792.
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. (2006) Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 24 (FGE.24): Pyridine, pyrrole, indole and quinoline derivatives from chemical group 28 (Commis. EFSA Journal 4:8, pages 372.
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. (2006) Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to Flavouring Group Evaluation 17 (FGE.17): Pyrazine derivatives from chemical group 24 (Comm. EFSA Journal 4:1, pages 295.
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T.B Adams, J Doull, V.J Feron, J.I Goodman, L.J Marnett, I.C Munro, P.M Newberne, P.S Portoghese, R.L Smith, W.J Waddell & B.M Wagner. (2002) The FEMA GRAS assessment of pyrazine derivatives used as flavor ingredients. Food and Chemical Toxicology 40:4, pages 429-451.
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David A. Cowan, Laurence H. Patterson, Lyaquatali A. Damani & John W. Gorrod. (1982) Metabolism of 4-substituted-N-ethyl-N-methylanilines: Chromatographic and mass spectrometric identification ofN-oxidation metabolic products formedin vitro. Biological Mass Spectrometry 9:6, pages 233-240.
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Lyaquatali A. Damani, Peter A. Crooks & David A. Cowan. (1981) Metabolism of metyrapone: 2—chromatographic and mass spectral properties of theN-oxides of metyrapone and metyrapol. Biological Mass Spectrometry 8:6, pages 270-277.
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