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Xenobiotica
the fate of foreign compounds in biological systems
Volume 10, 1980 - Issue 10
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Research Article

Species differences in the metabolism and excretion of fenclofenac

D. Greenslade Reckitt and Colman Ltd, Pharmaceutical Division, Dansom Lane, Hull, HU8 7DS, UK
,
M. E. Havler Reckitt and Colman Ltd, Pharmaceutical Division, Dansom Lane, Hull, HU8 7DS, UK
,
M. J. Humphrey Reckitt and Colman Ltd, Pharmaceutical Division, Dansom Lane, Hull, HU8 7DS, UK
,
B. J. Jordan Reckitt and Colman Ltd, Pharmaceutical Division, Dansom Lane, Hull, HU8 7DS, UK
&
M. J. Rance Reckitt and Colman Ltd, Pharmaceutical Division, Dansom Lane, Hull, HU8 7DS, UK
Pages 753-760 | Received 29 Nov 1979, Published online: 22 Sep 2008

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Ana C. S. P. S. de Jesus, Fernanda M. Costa, Paulo A. P. F. G. das Neves, Fernanda P. A. Melo, Antonio S. Silva, Osmarina P. P. Silva, Cleydson B. R. Santos & Rosivaldo S. Borges. (2019) The role of regioselective hydroxylation on toxicity of diclofenac and related derivatives. Molecular Simulation 45:17, pages 1454-1458.
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Mary Varwell Marsh, J. Caldwell, T. P. Sloan, R. L. Smith, Marian Horner & M. S. Moss. (1983) The metabolism of fenclofenac in the horse. Xenobiotica 13:4, pages 233-240.
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H. P. A. Illing. (1981) Techniques for microfloral and associated metabolic studies in relation to the absorption and enterohepatic circulation of drugs. Xenobiotica 11:12, pages 815-830.
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Articles from other publishers (8)

Zitao Guo, Mengling Liu, Jian Meng, Yaru Xue, Qi Huang, Yuandong Zheng, Yali Wu, Zhendong Chen, Jinghua Yu, Dafang Zhong, Guangze Li, Xiaoyan Chen & Xingxing Diao. (2022) Mechanistic Study on the Species Differences in Excretion Pathway of HR011303 in Humans and Rats. Drug Metabolism and Disposition 50:6, pages 809-818.
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Antonia F. Stepan, Daniel P. Walker, Jonathan Bauman, David A. Price, Thomas A. Baillie, Amit S. Kalgutkar & Michael D. Aleo. (2011) Structural Alert/Reactive Metabolite Concept as Applied in Medicinal Chemistry to Mitigate the Risk of Idiosyncratic Drug Toxicity: A Perspective Based on the Critical Examination of Trends in the Top 200 Drugs Marketed in the United States. Chemical Research in Toxicology 24:9, pages 1345-1410.
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F L S TseF BallardJ M JaffeH J Schwarz. (1983) Enterohepatic circulation of radioactivity following an oral dose of [14C]temazepam in the rat. Journal of Pharmacy and Pharmacology 35:4, pages 225-228.
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Yuan H Zhao, Michael H Abraham, Joelle Le, Anne Hersey, Chris N Luscombe, Gordon Beck, Brad Sherborne & Ian Cooper. (2003) Evaluation of rat intestinal absorption data and correlation with human intestinal absorption. European Journal of Medicinal Chemistry 38:3, pages 233-243.
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G.L. LARSEN. 1988. Role of the Gut Flora in Toxicity and Cancer. Role of the Gut Flora in Toxicity and Cancer 79 107 .
Francis L.S. Tse, Frances Ballard & James M. Jaffe. (1982) A practical method for monitoring drug excretion and enterohepatic circulation in the rat. Journal of Pharmacological Methods 7:2, pages 139-144.
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S.J. Capper, M.J. Humphrey & A.B. Kurtz. (1981) Inhibition of thyroxine binding to serum proteins by fenclofenac and related compounds. Clinica Chimica Acta 112:1, pages 77-83.
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A.A.J. Goldberg & K.E. Godfrey. (1980) Fenclofenac. Clinics in Rheumatic Diseases 6:3, pages 647-674.
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