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Xenobiotica
the fate of foreign compounds in biological systems
Volume 10, 1980 - Issue 9
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Original Article

Enterohepatic recycling of phenolphthalein, morphine, lysergic acid diethylamide (LSD) and diphenylacetic acid in the rat Hydrolysis of glucuronic acid conjugates in the gut lumen

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Pages 689-703 | Received 02 Jan 1980, Published online: 30 Sep 2009

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Rui Filipe Libânio Osório Marta. (2019) Metabolism of lysergic acid diethylamide (LSD): an update. Drug Metabolism Reviews 51:3, pages 378-387.
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Mohd Yaseen Malik, Swati Jaiswal, Abhisheak Sharma, Mahendra Shukla & Jawahar Lal. (2016) Role of enterohepatic recirculation in drug disposition: cooperation and complications. Drug Metabolism Reviews 48:2, pages 281-327.
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P. J. Simons, I. D. Cockshott, J. B. Glen, E. A. Gordon, S. Knott & R. J. Ruane. (1992) Disposition and pharmacology of propofol glucuronide administered intravenously to animals. Xenobiotica 22:11, pages 1267-1273.
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T. R. D. Elmhirst, J. K. Chipman, O. Ribeiro, P. C. Hirom & P. Millburn. (1985) Metabolism and enterohepatic circulation of benzo(a)pyrene-4,5-epoxide in the rat. Xenobiotica 15:11, pages 899-906.
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F L S TseF BallardJ M JaffeH J Schwarz. (1983) Enterohepatic circulation of radioactivity following an oral dose of [14C]temazepam in the rat. Journal of Pharmacy and Pharmacology 35:4, pages 225-228.
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Xiaohong Sun, Lili Niu, Xiaoqin Li, Xiumei Lu & Famei Li. (2009) Characterization of metabolic profile of mosapride citrate in rat and identification of two new metabolites: Mosapride N-oxide and morpholine ring-opened mosapride by UPLC–ESI-MS/MS. Journal of Pharmaceutical and Biomedical Analysis 50:1, pages 27-34.
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Steven Karch. 2008. Karch's Pathology of Drug Abuse, Fourth Edition. Karch's Pathology of Drug Abuse, Fourth Edition 367 374 .
Lisa J. Christopher, Donghui Cui, Wenying Li, Anthony BarrosJr.Jr., Vinod K. Arora, Haiying Zhang, Lifei Wang, Donglu Zhang, James A. Manning, Kan He, Anthony M. Fletcher, Marc Ogan, Michael Lago, Samuel J. Bonacorsi, W. Griffith Humphreys & Ramaswamy A. Iyer. (2008) Biotransformation of [ 14 C]Dasatinib: In Vitro Studies in Rat, Monkey, and Human and Disposition after Administration to Rats and Monkeys . Drug Metabolism and Disposition 36:7, pages 1341-1356.
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Lifei Wang, Donglu Zhang, Arun Swaminathan, Yongjun Xue, Peter T. Cheng, Shung Wu, Rogelio Mosqueda-Garcia, Catherine Aurang, Donald W. Everett & W. Griffith Humphreys. (2006) GLUCURONIDATION AS A MAJOR METABOLIC CLEARANCE PATHWAY OF 14 C-LABELED MURAGLITAZAR IN HUMANS: METABOLIC PROFILES IN SUBJECTS WITH OR WITHOUT BILE COLLECTION . Drug Metabolism and Disposition 34:3, pages 427-439.
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C.Edwin Garner, H.B. Matthews & L.T. Burka. (2000) Phenolphthalein Metabolite Inhibits Catechol-O-methyltransferase-Mediated Metabolism of Catechol Estrogens: A Possible Mechanism for Carcinogenicity. Toxicology and Applied Pharmacology 162:2, pages 124-131.
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Kathleen E. Heppert & Malonne I. Davies. (1999) Using a microdialysis shunt probe to monitor phenolphthalein glucuronide in rats with intact and diverted bile flow. Analytica Chimica Acta 379:3, pages 359-366.
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Jeffrey A. Wilhelm, Leonard C. Bailey, Theresa A. Shepard & Vincent S. Venturella. (1992) Simultaneous determination of phenolphthalein and phenolphthalein glucuronide from dog serum, urine and bile by high-performance liquid chromatography. Journal of Chromatography B: Biomedical Sciences and Applications 578:2, pages 231-238.
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Tonya L. Horton & Gary M. Pollack. (1991) Enterohepatic Recirculation and Renal Metabolism of Morphine in the Rat. Journal of Pharmaceutical Sciences 80:12, pages 1147-1152.
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E. F. Kuleshova, O. S. Anisimova & Yu. N. Sheinker. (1991) Use of chromatography and mass spectrometry in the study of drug metabolism (review). Pharmaceutical Chemistry Journal 25:3, pages 143-159.
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Robert Edwards, Peter Millburn & David H. Hutson. (2006) Comparative metabolism and disposition of [ 14 C‐benzyl ] cypermethrin in quail, rat and mouse . Pesticide Science 30:2, pages 159-181.
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William R. Sawyer & Robert B. Forney. (1988) Postmortem disposition of morphine in rats. Forensic Science International 38:3-4, pages 259-273.
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G.L. LARSEN. 1988. Role of the Gut Flora in Toxicity and Cancer. Role of the Gut Flora in Toxicity and Cancer 79 107 .
Richard A. Ahrens, Huan-Chi Hsu, Soon S. Kim, James P. Saunders & Larry W. Douglass. (1987) The Disaccharide Effect of Sucrose Feeding on Excretion of Intravenously Injected [1,2-3H]Aldosterone and Conjugated Glucuronic Acid in Normotensive Rats. The Journal of Nutrition 117:4, pages 689-693.
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SI Mui Sim & David J. Back. (1986) Intestinal absorption of oestrone, oestrone glucuronide and oestrone sulphate in the rat in situ—II. Studies with the Doluisio technique. Journal of Steroid Biochemistry 24:5, pages 1085-1089.
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Jelka Tomašić. 1983. Drug Metabolite Isolation and Determination. Drug Metabolite Isolation and Determination 149 160 .
Paolo Ventura, Sandro Serafini & Roberto Pria. (1982) Biotransformation of epomediol. Journal of Chromatography A 245:3, pages 350-354.
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Francis L.S. Tse, Frances Ballard & James M. Jaffe. (1982) A practical method for monitoring drug excretion and enterohepatic circulation in the rat. Journal of Pharmacological Methods 7:2, pages 139-144.
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D.J. Back, A.M. Breckenridge, Karen J. Cross, M.L'E. Orme & Elizabeth Thomas. (1982) An antibiotic interaction with ethinyloestradiol in the rat and rabbit. Journal of Steroid Biochemistry 16:3, pages 407-413.
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Paolo Ventura & Antonio Selva. (1982) Biotransformation of epomediol. I—isolation and identification of main metabolites in the rat. Biological Mass Spectrometry 9:1, pages 18-21.
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