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Xenobiotica
the fate of foreign compounds in biological systems
Volume 11, 1981 - Issue 2
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Research Article

Daunorubicin reduction mediated by aldehyde and ketone reductases

N. K. Ahmed Laboratory of Clinical Biochemistry, Baltimore Cancer Research Center, National Institutes of Health, University of Maryland Hospital, H.H., 655 West Baltimore Street, Baltimore, Maryland, 21201, USA
,
R. L. Felsted Laboratory of Clinical Biochemistry, Baltimore Cancer Research Center, National Institutes of Health, University of Maryland Hospital, H.H., 655 West Baltimore Street, Baltimore, Maryland, 21201, USA
&
N. R. Bachur Laboratory of Clinical Biochemistry, Baltimore Cancer Research Center, National Institutes of Health, University of Maryland Hospital, H.H., 655 West Baltimore Street, Baltimore, Maryland, 21201, USA
Pages 131-136 | Received 02 Aug 1980, Published online: 22 Sep 2008

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Frank Hoffmann & Edmund Maser. (2007) Carbonyl Reductases and Pluripotent Hydroxysteroid Dehydrogenases of the Short-chain Dehydrogenase/reductase Superfamily. Drug Metabolism Reviews 39:1, pages 87-144.
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Kathryn E. McLane, Jed Fisher & K. Ramakrishnan. (1983) Reductive Drug Metabolism. Drug Metabolism Reviews 14:4, pages 741-799.
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Articles from other publishers (14)

Daniel L. Gustafson & Dennis B. Bailey. 2019. Withrow and MacEwen's Small Animal Clinical Oncology. Withrow and MacEwen's Small Animal Clinical Oncology 182 208 .
Daniel L. Gustafson & Rodney L. Page. 2013. Withrow and MacEwen's Small Animal Clinical Oncology. Withrow and MacEwen's Small Animal Clinical Oncology 157 179 .
Dieter Lang & Amit Kalgutkar. 2003. Drug Metabolizing Enzymes. Drug Metabolizing Enzymes 483 539 .
Daniel L. Gustafson, Jeffrey C. Rastatter, Tina Colombo & Michael E. Long. (2002) Doxorubicin pharmacokinetics: Macromolecule binding, metabolism, and excretion in the context of a physiologic model. Journal of Pharmaceutical Sciences 91:6, pages 1488-1501.
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Xiuzohng Wu, Atsuko Noda, Hiroshi Noda & Yorishige Imamura. (2001) Side-chain metabolism of propranolol: involvement of monoamine oxidase and aldehyde reductase in the metabolism of N-desisopropylpropranolol to propranolol glycol in rat liver. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 129:4, pages 361-368.
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Karen WY Lee, Ben CB Ko, Zhirong Jiang, Deliang Cao & Stephen SM Chung. (2001) Overexpression of aldose reductase in liver cancers may contribute to drug resistance. Anti-Cancer Drugs 12:2, pages 129-132.
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Gerald L. Forrest & Basilio Gonzalez. (2000) Carbonyl reductase. Chemico-Biological Interactions 129:1-2, pages 21-40.
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Mary Ellen Mortensen, Anthony J. Cecalupo, Warren D. Lo, Merrill J. Egorin & Rosalind Batley. (1992) Inadvertent intrathecal injection of daunorubicin with fatal outcome. Medical and Pediatric Oncology 20:3, pages 249-253.
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Garth Powis. (1987) Metabolism and reactions of quinoid anticancer agents. Pharmacology & Therapeutics 35:1-2, pages 57-162.
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D T Molowa, A G Shayne & P S Guzelian. (1986) Purification and characterization of chlordecone reductase from human liver.. Journal of Biological Chemistry 261:27, pages 12624-12627.
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Geetha Vasanthakumar & Nahed K. Ahmed. (1986) Comparative uptake, retention and cytotoxicity of daunorubicin by human myeloid cells. Biochemical Pharmacology 35:7, pages 1185-1190.
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Nahed K. Ahmed. (1985) Daunorubicin reductase activity in human normal lymphocytes, myeloblasts and leukemic cell lines. European Journal of Cancer and Clinical Oncology 21:10, pages 1209-1213.
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Jeffrey R. Brown & S. Haider Imam. 1985. 169 236 .
Hermann Kappus & Helmut Sies. (1981) Toxic drug effects associated with oxygen metabolism: Redox cycling and lipid peroxidation. Experientia 37:12, pages 1233-1241.
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