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Xenobiotica
the fate of foreign compounds in biological systems
Volume 11, 1981 - Issue 3
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Research Article

The metabolism of pentachloromethylthiobenzene in germ-free and conventional rats

J. E. Bakke Metabolism and Radiation Research Laboratory, Agricultural Research, Science and Education Administration, US Department of Agriculture, Fargo, ND, 58105, USA
,
P. W. Aschbacher Metabolism and Radiation Research Laboratory, Agricultural Research, Science and Education Administration, US Department of Agriculture, Fargo, ND, 58105, USA
,
V. J. Feil Metabolism and Radiation Research Laboratory, Agricultural Research, Science and Education Administration, US Department of Agriculture, Fargo, ND, 58105, USA
&
B. E. Gustafsson Department of Germfree Research, Karolinska Institutet, Stockholm, Sweden
Pages 173-178 | Received 19 Jun 1980, Published online: 22 Sep 2008

Citations (21)

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Read on this site (9)

G. L. LARSEN. (1998) Intermediary metabolism of pentachloronitrobenzene in the control and germfree rat and rat with cannulated bile ducts. Xenobiotica 28:10, pages 973-984.
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Padmakar G. Deo, N. Ganesh Karanth, N. Gopalakrishna & K. Karanth. (1994) Biodegradation of Hexachlorocyclohexane Isomers in Soil and Food Environment. Critical Reviews in Microbiology 20:1, pages 57-78.
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J. E. Bakke, G. L. Larsen & K. L. Davison. (1994) Effect of AT-125 on the metabolism of propachlor and the glutathione conjugates of propachlor and bromobenzene in rat. Xenobiotica 24:9, pages 909-919.
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J. E. Bakke, D. J. Mulford, J. K. Huwe, V. J. Feil & K. L. Davison. (1993) Glutathione-mediated methylthio-turnover and sex differences in the metabolism of pentachlorothioanisole by rat. Xenobiotica 23:8, pages 949-960.
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D. J. Mulford, J. E. Bakke & V. J. Feil. (1991) Glutathione-S-transferase-medtated xnethylthio displacement and turnover in the metabolism of pentachlorothioanisole by rats. Xenobiotica 21:5, pages 597-603.
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J. K. Huwe, V. J. Feil, J. E. Bakke & D. J. Mulford. (1991) Studies on the displacement of methylthio groups by glutathione. Xenobiotica 21:2, pages 179-191.
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J. E. Bakke, V. J. Feil & D. J. Mulford. (1990) Biliary excretion and intestinal metabolism in the intermediary metabolism of pentachlorothioanisole. Xenobiotica 20:6, pages 601-605.
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J. E. Bakke & J.å Gustafsson. (1986) Role of intestinal flora in metabolism of agrochemicals conjugated with glutathione. Xenobiotica 16:10-11, pages 1047-1056.
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H. P. A. Illing. (1981) Techniques for microfloral and associated metabolic studies in relation to the absorption and enterohepatic circulation of drugs. Xenobiotica 11:12, pages 815-830.
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Articles from other publishers (12)

Jack R. Plimmer & Derek W. Gammon. 2003. Encyclopedia of Agrochemicals. Encyclopedia of Agrochemicals.
J. E. Bakke, V. J. Feil & R. G. Zaylskie. (1989) Isotope dilution assay for urinary methanesulfinic and methanesulfonic acids: Application to detection of methylthio turnover. Biological Mass Spectrometry 18:12, pages 1096-1098.
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Per Ola Darnerud, Ingvar Brandt, Vernon J. Feil & Jerome E. Bakke. (1988) S-(1,2-Dichloro-[14C]vinyl)-l-cysteine (DCVC) in the mouse kidney: Correlation between tissue-binding and toxicity. Toxicology and Applied Pharmacology 95:3, pages 423-434.
Crossref
G.L. LARSEN. 1988. Role of the Gut Flora in Toxicity and Cancer. Role of the Gut Flora in Toxicity and Cancer 79 107 .
R. M. Macholz & M. Kujawa. 1985. Residue Reviews. Residue Reviews 119 149 .
Ingvar Brandt, Abdulmalik Mohammed, Annika Lydéen & Premysl Slanina. (2009) Disposition of some Sulphur‐containing Hexachlorobenzene (HCB) Metabolites: Affinity of Methylsulphonylpentachlorobenzene for the Gray Matter of Brain, the Lungs and the Adrenal Zona reticularis **. Acta Pharmacologica et Toxicologica 54:5, pages 352-360.
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Jerome Bakke & Jan-Åke Gustafsson. (1984) Mercapturic acid pathway metabolites of xenobiotics: generation of potentially toxic metabolites during enterohepatic circulation. Trends in Pharmacological Sciences 5, pages 517-521.
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P.W. Aschbacher & A.D. Mitchell. (1983) Formation of S-(tetrachloromethylthiophenyl) glutathione from pentachloromethyl thiobenzene by isolated rat hepatocytes. Chemosphere 12:7-8, pages 961-965.
Crossref
J.E. Bakke. (1983) Metabolism of bis-methylthiotetrachlorobenzene in rats. Chemosphere 12:6, pages 793-798.
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J. E. Bakke, Å. L. Bergman & G. L. Larsen. (1982) Metabolism of 2,4′,5-Trichlorobiphenyl by the Mercapturic Acid Pathway. Science 217:4560, pages 645-647.
Crossref
Å. Bergman, A. Biessmann, I. Brandt & J. Rafter. (1982) Metabolism of 2,4′,5-trichlorobiphenyl: Role of the intestinal microflora in the formation of bronchial-seeking methyl sulphone metabolites in mice. Chemico-Biological Interactions 40:2, pages 123-131.
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J. E. Bakke. (1982) Conversion of the prosthetic moieties of glutathione pathway conjugates to the correspondingS- acetates. Biological Mass Spectrometry 9:2, pages 74-77.
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