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Xenobiotica
the fate of foreign compounds in biological systems
Volume 11, 1981 - Issue 4
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Research Article

Identification of urinary mercapturic acids formed from acrylate, methacrylate and crotonate in the rat

L. P. C. Delbressine Department of Dermatology, University of Nijmegen, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands; Department of Pharmacology, University of Nijmegen, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands
,
F. Seutter-Berlage Department of Pharmacology, University of Nijmegen, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands
&
E. Seutter Department of Dermatology, University of Nijmegen, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands
Pages 241-247 | Received 14 Jul 1980, Published online: 22 Sep 2008

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Jonathan Borak, Cheryl Fields, Larry S. Andrews & Mark A. Pemberton. (2011) Methyl methacrylate and respiratory sensitization: A Critical review. Critical Reviews in Toxicology 41:3, pages 230-268.
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I. Linhart, M. Vosmanská & J. ŠMejkal. (1994) Biotransformation of acrylates. Excretion of mercapturic acids and changes in urinary carboxylic acid profile in rat dosed with ethyl and 1-butyl acrylate. Xenobiotica 24:10, pages 1043-1052.
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Articles from other publishers (39)

Axel Wibbertmann, Annette Bitsch & Christine Frieke Kuper. (2021) Comprehensive analysis of chronic rodent inhalation toxicity studies for methyl acrylate with attention to test conditions exceeding a maximum tolerated concentration. Regulatory Toxicology and Pharmacology 122, pages 104900.
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Mina Suh, Deborah Proctor, Grace Chappell, Julia Rager, Chad Thompson, Susan Borghoff, Lavorgie Finch, Robert Ellis-Hutchings & Karin Wiench. (2018) A review of the genotoxic, mutagenic, and carcinogenic potentials of several lower acrylates. Toxicology 402-403, pages 50-67.
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Heidi Peters, Sacha Ferdinandusse, Jos P. Ruiter, Ronald J.A. Wanders, Avihu Boneh & James Pitt. (2015) Metabolite studies in HIBCH and ECHS1 defects: Implications for screening. Molecular Genetics and Metabolism 115:4, pages 168-173.
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Atsushi Takamizawa, Kayoko Mishina & Kenzo Hiraoka. (2012) Observation of dimethylaminoethyl methacrylate–myoglobin binding reaction using laser spray mass spectrometry. Journal of Mass Spectrometry 47:2, pages 221-225.
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. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 254 262 .
. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 9 .
. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 196 231 .
. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 30 .
. (2010) Flavouring Group Evaluation 5, Revision 2 (FGE.05Rev2): Branched- and straight-chain unsaturated carboxylic acids and esters of these with aliphatic saturated alcohols from chemical groups 1, 2, 3 and 5. EFSA Journal 8:10, pages 1400.
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Marina C. Jeppsson, Harriet Mörtstedt, Giovanni Ferrari, Bo A.G. Jönsson & Christian H. Lindh. (2010) Identification of covalent binding sites of ethyl 2-cyanoacrylate, methyl methacrylate and 2-hydroxyethyl methacrylate in human hemoglobin using LC/MS/MS techniques. Journal of Chromatography B 878:27, pages 2474-2482.
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. (2008) Flavouring Group Evaluation 5, Revision 1 (FGE.05Rev1):Esters of branched‐ and straight‐chain aliphatic saturated primary alcohols and of one secondary alcohol, and branched‐ and straight‐chain unsaturated carboxylic acids from chemical groups 1, 2, and 5 (Commission Regulation (EC) No 1565/2000 of 18 July 2000) ‐ Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC). EFSA Journal 6:3.
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Raymond A. Kemper, Diane L. Nabb, Shawn A. Gannon, Timothy A. Snow & Anne Marie Api. (2006) COMPARATIVE METABOLISM OF GERANYL NITRILE AND CITRONELLYL NITRILE IN MOUSE, RAT, AND HUMAN HEPATOCYTES. Drug Metabolism and Disposition 34:6, pages 1019-1029.
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. (2005) Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 5 (FGE.05); Esters of 23 branched- and straight-chain aliphatic saturated primary alcohols and. EFSA Journal 3:7, pages 204.
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Leena A. Nylander-French & John E. French. (2016) Tripropylene Glycol Diacrylate but Not Ethyl Acrylate Induces Skin Tumors in a Twenty-Week Short-Term Tumorigenesis Study in Tg.AC (v-Ha- ras ) Mice . Toxicologic Pathology 26:4, pages 476-483.
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R. R. Tice, L. A. Nylander-French & J. E. French. (1997) Absence of systemic in vivo genotoxicity after dermal exposure to ethyl acrylate and tripropylene glycol diacrylate in Tg.AC (v-Ha-ras) mice. Environmental and Molecular Mutagenesis 29:3, pages 240-249.
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H. Greim, J. Ahlers, R. Bias, B. Broecker, H. Hollander, H.-P. Gelbke, S. Jacobi, H.-J. Klimisch, I. Mangelsdorf, W. Mayr, N. Schön, G. Stropp, P. Stahnecker, R. Vogel, C. Weber, K. Ziegler-Skylakakis & E. Bayer. (1995) Assessment of structurally related chemicals: Toxicity and ecotoxicity of acrylic acid and acrylic acid alkyl esters (acrylates), methacrylic acid and methacrylic acid alkyl esters (methacrylates). Chemosphere 31:2, pages 2637-2659.
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A. Daniel Jones, Carl K. Winter, Michael H. Buonarati & H. J. Segall. (1993) Analysis of mercapturic acid conjugates of xenobiotic compounds using negative ionization and tandem mass spectrometry. Biological Mass Spectrometry 22:1, pages 68-76.
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Pavel Vodička, Ivan Gut & Emil Frantík. (1990) Effects of inhaled acrylic acid derivatives in rats. Toxicology 65:1-2, pages 209-221.
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. 1990. Pharmacology of Neuromuscular Function. Pharmacology of Neuromuscular Function 249 310 .
R Rajaniemi, P Pfaffli & H Savolainen. (1989) Percutaneous absorption of methyl methacrylate by dental technicians.. Occupational and Environmental Medicine 46:5, pages 356-357.
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V. Nigrovic, J. B. Pandya, J. E. Klaunig & K. Fry. (1989) Reactivity and toxicity of atracurium and its metabolitesin vitro. Canadian Journal of Anaesthesia 36:3, pages 262-268.
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Vladimir Nigrovic, William Gallup, Jyoti Pandya & Kelvin Fry. (1989) Generation of Reactive Metabolites During Spontaneous Degradation of Atracurium In Vitro. The American Journal of the Medical Sciences 297:1, pages 12-17.
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Ivan Gut, Pavel Vodička, Miroslav Cikrt, Andrzej Sapota & Ivo Kavan. (1988) Distribution and elimination of (14C)-2-ethylhexyl acrylate radioactivity in rats. Archives of Toxicology 62:5, pages 346-350.
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E. C. Rietveld, F. J. C. van Gastel, F. Seutter-Berlage & B. Zwanenburg. (1988) Glutathione conjugation and bacterial mutagenicity of racemic and enantiomerically pure cis-and trans-methyl epoxycinnamates. Archives of Toxicology 61:5, pages 366-372.
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Andrzej Sapota. (1988) The disposition of [2,3-14C]-methyl and [2,3-14C]-2-ethylhexyl acrylate in male wistar albino rats. Archives of Toxicology 62:2-3, pages 181-184.
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Martha M. Moore, Amanda Amtower, Carolyn L. Doerr, Karen H. Brock & Kerry L. Dearfield. (1988) Genotoxicity of acrylic acid, methyl acrylate, ethyl acrylate, methyl methacrylate, and ethyl methacrylate in l5178y mouse lymphoma cells. Environmental and Molecular Mutagenesis 11:1, pages 49-63.
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Joachim Jandke & Gerhard Spiteller. (1987) Unusual conjugates in biological profiles originating from consumption of onions and garlic. Journal of Chromatography B: Biomedical Sciences and Applications 421, pages 1-8.
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Jan Kopecký, Jaroslav Šmejkal, Igor Linhart, Vladimir Hanuš, J. Heyrovský & Pavel Pech. (2010) A Note on the Synthesis of Methacrylate-Derived Mercapturic Acid Methyl Esters. Bulletin des Sociétés Chimiques Belges 95:12, pages 1123-1127.
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J�rgen N�rrelykke Nissen & Leif Corydon. (1985) Corneal ulcer after exposure to vapours from bone cement (methyl metacrylate and hydroquinone). International Archives of Occupational and Environmental Health 56:2, pages 161-165.
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W. Onkenhout, N. P. E. Vermeulen, W. C. M. M. Luijten & H. J. de Jong. (1983) Electron impact mass spectrometric analysis of mercapturic acid methyl esters. Fragmentation of mercapturic acid methyl esters according to ‘retro-Michael’ reactions. Biological Mass Spectrometry 10:11, pages 614-619.
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Th. H. Waegemaekers & H. B. van der Walle. (2006) The sensitizing potential of 2‐ethylhexyl acrylate in the guinea pig * . Contact Dermatitis 9:5, pages 372-376.
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A. L. Burlingame, K. Straub & T. A. Baillie. (2005) Mass spectrometric studies on the molecular basis of xenobiotic‐induced toxicities. Mass Spectrometry Reviews 2:3, pages 331-387.
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W. Draminski, E. Eder & D. Henschler. (1983) A new pathway of acrolein metabolism in rats. Archives of Toxicology 52:3, pages 243-247.
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Eivor Elovaara, Helena Kivist� & Harri Vainio. (1983) Effects of methyl methacrylate on non-protein thiols and drug metabolizing enzymes in rat liver and kidneys. Archives of Toxicology 52:2, pages 109-121.
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Jelka Tomašić. 1983. Drug Metabolite Isolation and Determination. Drug Metabolite Isolation and Determination 149 160 .
W. Onkenhout, G.J. Guijt, H.J. de Jong & N.P.E. Vermeulen. (1982) Capillary gas chromatographic analysis of mercapturic acids. Journal of Chromatography A 243:2, pages 362-367.
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E. VAN DIJK & J. W. H. MALI. (1982) Proceedings of the 222nd Meeting of the Netherlands Society for Dermatology and Venereology, Nijmegen, 16 May 1981. British Journal of Dermatology 106:5, pages 603-612.
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L. P. C. Delbressine, H. C. J. G. van Balen & F. Seutter-Berlage. (1982) Isolation and identification of mercapturic acid metabolites of phenyl substituted acrylate esters from urine of female rats. Archives of Toxicology 49:3-4, pages 321-330.
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Jerome Edelson, DavidP. Benziger & JamesF. Baker. 1982. 333 342 .

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