Advanced search
Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 11, 1981 - Issue 12
Submit an article Journal homepage
15
Views
19
CrossRef citations to date
0
Altmetric
Original Article

A novel technique for assessment of biliary secretion and enterohepatic circulation in the unrestrained conscious rat

P. W. Tomlinson Beecham Pharmaceuticals Research Division, Drug Metabolism Unit, Coldharbour Road, The Pinnacles, Harlow, Essex, UK
,
D. J. Jeffery Beecham Pharmaceuticals Research Division, Drug Metabolism Unit, Coldharbour Road, The Pinnacles, Harlow, Essex, UK
&
C. W. Filer Beecham Pharmaceuticals Research Division, Drug Metabolism Unit, Coldharbour Road, The Pinnacles, Harlow, Essex, UK
Pages 863-870 | Received 14 Jul 1981, Published online: 30 Sep 2009

Citations (19)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (7)

D. McKILLOP*C. J. BUTTERS, S. J. HILL, P. J. SIMONS, T. L. EDWARDS & S. E. DOUGHTY. (1998) Enzyme-inducing effects of bicalutamide in mouse, rat and dog. Xenobiotica 28:5, pages 465-478.
Read now
G. C. Bolton, J. P. Keogh, P. D. East, F. J. Hollis & A. D. Shore. (1996) The fate of a thiazolidinedione antidiabetic agent in rat and dog. Xenobiotica 26:6, pages 627-636.
Read now
D. McKillop, P. J. Simons, I. D. Cockshott, S. J. Hill, J. R. Harding, K. J. Cooper & D. C. Jones. (1995) Enantioselective metabolism and pharmacokinetics of Casodex in the male rat. Xenobiotica 25:6, pages 623-633.
Read now
S. E. Clarke, N. E. Austin, J. C. Bloomer, R. E. Haddock, F. C. Higham, F. J. Hollis, M. Nash, P. C. Shardlow, T. C. Tasker, F. R. Woods & G. D. Allen. (1994) Metabolism and disposition of 14C-granisetron in rat, dog and man after intravenous and oral dosing. Xenobiotica 24:11, pages 1119-1131.
Read now
G. W. Boyle, D. McKillop, P. J. Phillips, J. R. Harding, R. Pickford & A. D. McCormick. (1993) Metabolism of Casodex in laboratory animals. Xenobiotica 23:7, pages 781-798.
Read now
P. W. Tomlinson, J. V. Ramji & C. W. Filer. (1992) Disposition of the enantiomers of cromakalim in rat and cynomolgus monkey. Xenobiotica 22:7, pages 799-814.
Read now
I. S. Silver & W. C. Dauterman. (1989) The Pharmacokinetics and Metabolism of (1r, Cis)- and (1r, Trans)-Tetramethrin in Rats. Xenobiotica 19:3, pages 301-314.
Read now

Articles from other publishers (12)

Alexander V. LyubimovTsuhan Lin, Tycho Heimbach, Rakesh Gollen & Handan He. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions 1 39 .
Hiroki Ishibashi, Tomomi Kuwahara, Haruyuki Nakayama-Imaohji, Yoshinari Ohnishi, Hiroki Mori & Mitsuo Shimada. (2012) Effects of indole-3-carbinol and phenethyl isothiocyanate on bile and pancreatic juice excretion in rats. The Journal of Medical Investigation 59:3.4, pages 246-252.
Crossref
Stephen J.P. Damment & Michael Pennick. (2007) Systemic lanthanum is excreted in the bile of rats. Toxicology Letters 171:1-2, pages 69-77.
Crossref
Mehmet Erkut Kara. (2005) The anatomical study on the rat pancreas and its ducts with emphasis on the surgical approach. Annals of Anatomy - Anatomischer Anzeiger 187:2, pages 105-112.
Crossref
René Remie. 2000. The Laboratory Rat. The Laboratory Rat 523 568 .
M. A. DunnM. H. GreenR. M. LeachJrJr. (1991) Kinetics of copper metabolism in rats: a compartmental model. American Journal of Physiology-Endocrinology and Metabolism 261:1, pages E115-E125.
Crossref
Michael J. Basker, Stephen C. Finch & John W. Tyler. (1990) Use of 1H NMR in the identification of a metabolite of a catecholic cephalosporin excreted in rat bile. Journal of Pharmaceutical and Biomedical Analysis 8:7, pages 573-576.
Crossref
K. P. R. Gartland, C. T. Eason, F. W. Bonner & J. K. Nicholson. (1990) Effects of biliary cannulation and buthionine sulphoximine pretreatment on the nephrotoxicity of para-aminophenol in the Fischer 344 rat. Archives of Toxicology 64:1, pages 14-25.
Crossref
K.P.R. Gartland, C.T. Eason, K.E. Wade, F.W. Bonner & J.K. Nicholson. (1989) Proton NMR spectroscopy of bile for monitoring the excretion of endogenous and xenobiotic metabolites: Application to para-aminophenol. Journal of Pharmaceutical and Biomedical Analysis 7:6, pages 699-707.
Crossref
K. P. R. Gartland, C. T. Eason, F. W. Bonner & J. K. Nicholson. 1989. Nephrotoxicity. Nephrotoxicity 423 432 .
Y.H. Park, C.B. Wooldridge, J. Mattern, M.L. Stoltz & R.K. Brazzell. (1988) Disposition of the Aldose Reductase Inhibitor AL01576 in Rats. Journal of Pharmaceutical Sciences 77:2, pages 110-115.
Crossref
R G Turcan, C M MacDonald, R M Ings & J D Coombes. (1985) Inhibition of the rate of 14CO2 production from [14C]ethanol in rats given beta-lactam antibiotics with disulfiram-like effects. Antimicrobial Agents and Chemotherapy 27:4, pages 535-540.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.