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Xenobiotica
the fate of foreign compounds in biological systems
Volume 11, 1981 - Issue 7
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Research Article

Differences in the biotransformation of a 17β-hydroxylated steroid, trenbolone acetate, in rat and cow

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Pages 489-500 | Received 01 Dec 1980, Published online: 22 Sep 2008

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I. G. Lange, A. Daxenberger, H. H. D. Meyer, E. Rajpert-De Meyts, N. E. Skakkebæk & D. N. R. Veeramachaneni. (2002) Quantitative assessment of foetal exposure to trenbolone acetate, zeranol and melengestrol acetate, following maternal dosing in rabbits. Xenobiotica 32:8, pages 641-651.
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Shih-Shien Hsu, ThomasR. Covey & JackD. Henion. (1987) Determination of Trenbolone in Bovine Liver and Muscle by HPLC and LC/MS/MS. Journal of Liquid Chromatography 10:14, pages 3033-3045.
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Joseph A. Robinson, Qingli Ma, Jane P. Staveley & Walter J. Smolenski. (2017) Sorption and desorption of 17α‐trenbolone and trendione on five soils. Environmental Toxicology and Chemistry 36:3, pages 613-620.
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Joseph A. Robinson, Qingli Ma, Jane P. Staveley, Walter J. Smolenski & Jon Ericson. (2016) Degradation and transformation of 17α‐trenbolone in aerobic water–sediment systems. Environmental Toxicology and Chemistry 36:3, pages 630-635.
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Yun Zhang, Daniel D. Snow & Shannon L. Bartelt-Hunt. (2016) Stereoselective Degradation of Estradiol and Trenbolone Isomers in Alluvial Sediment. Environmental Science & Technology 50:24, pages 13256-13264.
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D. G. Donner, G. E. Elliott, B. R. Beck, M. R. Forwood & E. F. Du Toit. (2015) The effects of visceral obesity and androgens on bone: trenbolone protects against loss of femoral bone mineral density and structural strength in viscerally obese and testosterone-deficient male rats. Osteoporosis International 27:3, pages 1073-1082.
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Daniel G. Donner, Grace E. Elliott, Belinda R. Beck, Andrew C. Bulmer, Alfred K. Lam, John P. Headrick & Eugene F. Du Toit. (2016) Trenbolone Improves Cardiometabolic Risk Factors and Myocardial Tolerance to Ischemia-Reperfusion in Male Rats With Testosterone-Deficient Metabolic Syndrome. Endocrinology 157:1, pages 368-381.
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Brett R. Blackwell, Bradley J. Johnson, Michael D. Buser, George P. Cobb & Philip N. Smith. (2015) Transformation kinetics of trenbolone acetate metabolites and estrogens in urine and feces of implanted steers. Chemosphere 138, pages 901-907.
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Emily A. Cole, Samantha A. McBride, Kaitlin C. Kimbrough, Jaewoong Lee, Eric A. Marchand, David M. Cwiertny & Edward P. Kolodziej. (2015) Rates and product identification for trenbolone acetate metabolite biotransformation under aerobic conditions. Environmental Toxicology and Chemistry 34:7, pages 1472-1484.
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Keeve E. Nachman & Tyler J. S. Smith. (2015) Hormone Use in Food Animal Production: Assessing Potential Dietary Exposures and Breast Cancer Risk. Current Environmental Health Reports 2:1, pages 1-14.
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Brett R. Blackwell, Tyson R. Brown, Paul R. Broadway, Michael D. Buser, J. Chance Brooks, Bradley J. Johnson, George P. Cobb & Philip N. Smith. (2014) Characterization of trenbolone acetate and estradiol metabolite excretion profiles in implanted steers. Environmental Toxicology and Chemistry 33:12, pages 2850-2858.
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Kristy L Forsgren, Shen Qu, Ramon Lavado, David Cwiertny & Daniel Schlenk. (2014) Trenbolone acetate metabolites promote ovarian growth and development in adult Japanese medaka (Oryzias latipes). General and Comparative Endocrinology 202, pages 1-7.
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Bryson E. Finch, Brett R. Blackwell, Derek R. Faust, Kimberly J. Wooten, Jonathan D. Maul, Stephen B. Cox & Philip N. Smith. (2012) Effects of 17α-trenbolone and melengestrol acetate on Xenopus laevis growth, development, and survival. Environmental Science and Pollution Research 20:2, pages 1151-1160.
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B.R. Blackwell, A. Karnjanapiboonwong, T.A. Anderson & P.N. Smith. (2012) Uptake of 17β-trenbolone and subsequent metabolite trendione by the pinto bean plant (Phaseolus vulgaris). Ecotoxicology and Environmental Safety 85, pages 110-114.
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Bushra Khan & Linda S. Lee. (2012) Estrogens and synthetic androgens in manure slurry from trenbolone acetate/estradiol implanted cattle and in waste-receiving lagoons used for irrigation. Chemosphere 89:11, pages 1443-1449.
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K.S. Schmidt, R. Hackenberg, C.S. Stachel & P. Gowik. (2012) Endogenous and synthetic steroids in bovine urine – Preparation of in-house reference material, stability studies and results of a proficiency test. Analytica Chimica Acta 717, pages 85-91.
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B.R. Blackwell, Q. Cai, P.N. Smith & G.P. Cobb. (2011) Liquid chromatography–tandem mass spectrometry analysis of 17α-trenbolone, 17β-trenbolone and trendione in airborne particulate matter. Talanta 85:3, pages 1317-1323.
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Melanie Boettcher, Thomas Kosmehl & Thomas Braunbeck. (2011) Low-dose effects and biphasic effect profiles: Is trenbolone a genotoxicant?. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 723:2, pages 152-157.
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H. Mash. (2010) Assessing the fate and transformation by-product potential of trenbolone during chlorination. Chemosphere 81:7, pages 946-953.
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Jane E. Morthorst, Henrik Holbech & Poul Bjerregaard. (2010) Trenbolone causes irreversible masculinization of zebrafish at environmentally relevant concentrations. Aquatic Toxicology 98:4, pages 336-343.
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Bushra Khan & Linda S. Lee. (2010) Soil temperature and moisture effects on the persistence of synthetic androgen 17α-trenbolone, 17β-trenbolone and trendione. Chemosphere 79:8, pages 873-879.
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Irmgard Riedmaier, Ales Tichopad, Martina Reiter, Michael W. Pfaffl & Heinrich H.D. Meyer. (2009) Identification of potential gene expression biomarkers for the surveillance of anabolic agents in bovine blood cells. Analytica Chimica Acta 638:1, pages 106-113.
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