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Xenobiotica
the fate of foreign compounds in biological systems
Volume 11, 1981 - Issue 11
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Research Article

Microsomal dechlorination of chloroethanes: Structure-reactivity relationships

A. G. Salmon Imperial Chemical Industries Limited, Central Toxicology Laboratory, Alderley Park, Nr. Macclesfield, Cheshire, SK10 4TJ, UK
,
R. B. Jones Imperial Chemical Industries Limited, Corporate Laboratory, The Heath, Runcorn, Cheshire, WA7 4QE, UK
&
W. C. Mackrodt Imperial Chemical Industries Limited, Corporate Laboratory, The Heath, Runcorn, Cheshire, WA7 4QE, UK
Pages 723-734 | Received 14 Jul 1981, Published online: 22 Sep 2008

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Michael L. Gargas, Harvey J. Clewell & Melvin E. Andersen. (1990) Gas Uptake Inhalation Techniques and the Rates of Metabolism of Chloromethanes, Chloroethanes, and Chloroethylenes in the Rat. Inhalation Toxicology 2:3, pages 295-319.
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Ellen M. Faed. (1984) Properties of Acyl Glucuronides: Implications for Studies of the Pharmacokinetics and Metabolism of Acidic Drugs. Drug Metabolism Reviews 15:5-6, pages 1213-1249.
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Articles from other publishers (14)

Heidrun Greim. 2024. Encyclopedia of Toxicology. Encyclopedia of Toxicology 237 247 .
S.B. Jazayeri, R. Bazl, M. Biglar & M. Amanlou. 2014. Encyclopedia of Toxicology. Encyclopedia of Toxicology 882 889 .
J.E. Barbash. 2014. Treatise on Geochemistry. Treatise on Geochemistry 535 572 .
Patricia Ellis, Michelle Kenyon & Krista Dobo. (2013) Determination of compound-specific acceptable daily intakes for 11 mutagenic carcinogens used in pharmaceutical synthesis. Regulatory Toxicology and Pharmacology 65:2, pages 201-213.
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George M. Rusch. 2003. Patty's Toxicology. Patty's Toxicology 359 427 .
J.E. Barbash. 2007. Treatise on Geochemistry. Treatise on Geochemistry 1 43 .
George M. Rusch. 2001. Patty's Toxicology. Patty's Toxicology.
George M. Rusch. 2003. Patty's Toxicology. Patty's Toxicology.
Michael L. Gargas & Melvin E. Andersen. (1989) Determining kinetic constants of chlorinated ethane metabolism in the rat from rates of exhalation. Toxicology and Applied Pharmacology 99:2, pages 344-353.
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A G Salmon, J A Nash, C M Walklin & R B Freedman. (1985) Dechlorination of halocarbons by microsomes and vesicular reconstituted cytochrome P-450 systems under reductive conditions.. Occupational and Environmental Medicine 42:5, pages 305-311.
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YIN-TAK WOO, DAVID Y. LAI, JOSEPH C. ARCOS & MARY F. ARGUS. 1985. Aliphatic and Polyhalogenated Carcinogens. Aliphatic and Polyhalogenated Carcinogens 415 462 .
John A. Thompson, Bert Ho & Susan L. Mastovich. (1984) Reductive metabolism of 1,1,1,2-tetrachloroethane and related chloroethanes by rat liver microsomes. Chemico-Biological Interactions 51:3, pages 321-333.
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Charles A. Tyson, Katherine Hawk-Prather, David L. Story & David H. Gould. (1983) Correlations of in vitro and in vivo hepatotoxicity for five haloalkanes. Toxicology and Applied Pharmacology 70:2, pages 289-302.
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Russell A. Van Dyke. (1983) Halogenated Anaesthetic Hepatotoxicity— Is the Answer Close at Hand?. Clinics in Anaesthesiology 1:2, pages 485-506.
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