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Xenobiotica
the fate of foreign compounds in biological systems
Volume 11, 1981 - Issue 11
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Research Article

The biotransformation of [14C]minaprine in man and five animal species

H. Davi Centrede recherches CLIN-MIDY, Department of Drug Metabolism and Pharmacokinetics, Rue du Professor J. Blayac, F-34082, Montpellier, France
,
P. Dupont Centrede recherches CLIN-MIDY, Department of Drug Metabolism and Pharmacokinetics, Rue du Professor J. Blayac, F-34082, Montpellier, France
,
J. P. Jeanniot Centrede recherches CLIN-MIDY, Department of Drug Metabolism and Pharmacokinetics, Rue du Professor J. Blayac, F-34082, Montpellier, France
,
R. Roncucci Centrede recherches CLIN-MIDY, Department of Drug Metabolism and Pharmacokinetics, Rue du Professor J. Blayac, F-34082, Montpellier, France
&
W. Cautreels Centrede recherches CLIN-MIDY, Department of Drug Metabolism and Pharmacokinetics, Rue du Professor J. Blayac, F-34082, Montpellier, France
Pages 735-747 | Received 05 Jan 1981, Published online: 22 Sep 2008

Citations (15)

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H. Davi, J. M. Bonnet & Y. Berger. (1992) Disposition of minaprine in animals and in human extensive and limited debrisoquine hydroxylators. Xenobiotica 22:2, pages 171-184.
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E. Lacarelle, F. Marre, A. Durand, H. Davi & R. Rahmani. (1991) Metabolism of minaprine in human and animal hepatocytes and liver microsomes—prediction of metabolism in vivo. Xenobiotica 21:3, pages 317-329.
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S. Caccia, T. Fossati & A. Mancinelli. (1985) Disposition and Metabolism of Minaprine in the Rat. Xenobiotica 15:12, pages 1111-1119.
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H. Davi, A. Carayon, E. Marti, Y. Sales & W. Cautreels. (1985) Circulating and brain metabolites of minaprine in the baboon. Xenobiotica 15:2, pages 97-106.
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Articles from other publishers (11)

H. Gökce & S. Bahçeli. (2014) Molecular structure, spectroscopic properties (FT-IR, Micro-Raman, and UV-vis), and DFT calculations of minaprine. Optics and Spectroscopy 117:1, pages 82-95.
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P Ferretti, S Algeri, F Benfenati, M Cimino, C Ferretti, S Garattini & M Lipartiti. (1984) Biochemical effects of minaprine on striatal dopaminergic neurons in rats. Journal of Pharmacy and Pharmacology 36:1, pages 48-50.
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Laura K. Chico, Heather A. Behanna, Wenhui Hu, Guifa Zhong, Saktimayee Mitra Roy & D. Martin Watterson. (2009) Molecular Properties and CYP2D6 Substrates: Central Nervous System Therapeutics Case Study and Pattern Analysis of a Substrate Database. Drug Metabolism and Disposition 37:11, pages 2204-2211.
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Camille G. Wermuth. (2006) Selective optimization of side activities: the SOSA approach. Drug Discovery Today 11:3-4, pages 160-164.
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Camille‐Georges Wermuth. (2009) Search for new lead compounds: The example of the chemical and pharmacological dissection of aminopyridazines. Journal of Heterocyclic Chemistry 35:5, pages 1091-1100.
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Gottfried Heinisch & Hannelore Frank. 1990. 1 49 .
Paul Worms, Jean-Paul Kan, Regis Steinberg, Jean-Paul Terranova, Alain Perio & Kathleen Biziere. (1989) Cholinomimetic activities of minaprine. Naunyn-Schmiedeberg's Archives of Pharmacology 340:4, pages 411-418.
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Florent Isel & Paul Mandel. (1989) Alterations of serotonin neurotransmission and inhibition of mouse-killing behavior: III Effects of minaprine, CM 30366 and SR 95191. Pharmacology Biochemistry and Behavior 33:3, pages 655-662.
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Jean-Paul Kan, Claire Mouget-Goniot, Paul Worms & Kathleen Biziere. (1986) Effect of the antidepressant minaprine on both forms of monoamine oxidase in the rat. Biochemical Pharmacology 35:6, pages 973-978.
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S. Garattini, G. L. Forloni, S. Tirelli, H. Ladinsky & S. Consolo. (1984) Neurochemical effects of minaprine, a novel psychotropic drug, on the central cholinergic system of the rat. Psychopharmacology 82:3, pages 210-214.
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M.H. Fong, A. Abbiati, E. Benfenati & S. Caccia. (1983) Quantitative analysis of minaprine and some of its metabolites with application to kinetic studies in rats. Journal of Chromatography A 259, pages 141-149.
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