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Xenobiotica
the fate of foreign compounds in biological systems
Volume 11, 1981 - Issue 11
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Research Article

The comparative metabolism of 2-bromoethanol and ethylene oxide in the rat

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Pages 763-770 | Received 15 Jun 1981, Published online: 22 Sep 2008

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R. G. Liteplo, M. E. Meek & W. Bruce. (2001) ETHYLENE OXIDE: HAZARD CHARACTERIZATION AND EXPOSURE–RESPONSE ANALYSIS. Journal of Environmental Science and Health, Part C 19:1, pages 219-265.
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Ronald T. H. van Welie, Rob G. J. M. van Dijck, Nico P. E. Vermeulen & Nico J. van Sittert. (1992) Mercapturic Acids, Protein Adducts, and DNA Adducts as Biomarkers of Electrophilic Chemicals. Critical Reviews in Toxicology 22:5-6, pages 271-306.
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M. S. Dobbie, K. E. Porter & A. R. Jones. (1988) Is the Nephrotoxicity of (R)-3-Chlorolactate in the Rat Caused by 3-Chloropyruvate?. Xenobiotica 18:12, pages 1389-1399.
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John A. McKelvey & Michael A. Zemaitis. (1986) The Effects of Ethylene Oxide (EO) Exposure on Tissue Glutathione Levels in Rats and Mice. Drug and Chemical Toxicology 9:1, pages 51-66.
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Joanna Klapacz & Claire Doskey. 2003. Patty's Toxicology. Patty's Toxicology 1 59 .
Jaroslav Mráz, Iveta Hanzlíková, Igor Linhart, Šárka Dušková, Ludmila Dabrowská & Kamil Hejl. (2019) N-(2-Hydroxyethyl)-l-valyl-l-leucine in rat urine as a hydrolytic cleavage product of ethylene oxide adduct with globin. Archives of Toxicology 93:3, pages 603-613.
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Hongwei Hou, Wei Xiong, Na Gao, Xiaotao Zhang, Gangling Tang & Qingyuan Hu. (2012) A column-switching liquid chromatography–tandem mass spectrometry method for quantitation of 2-cyanoethylmercapturic acid and 2-hydroxyethylmercapturic acid in Chinese smokers. Analytical Biochemistry 430:1, pages 75-82.
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Lynn H. Pottenger, Darrell R. Boverhof & John M. WaechterJr.Jr.. 2003. Patty's Toxicology. Patty's Toxicology 425 490 .
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H. M. Bolt. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 8 .
Lode Godderis, Peter Aka, Raluca Mateuca, Micheline Kirsch-Volders, Dominique Lison & Hendrik Veulemans. (2006) Dose-dependent influence of genetic polymorphisms on DNA damage induced by styrene oxide, ethylene oxide and gamma-radiation. Toxicology 219:1-3, pages 220-229.
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Roman Kubec, Seokwon Kim & Rabi A. Musah. (2002) S-Substituted cysteine derivatives and thiosulfinate formation in Petiveria alliacea—part II. Phytochemistry 61:6, pages 675-680.
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Timothy R. Fennell & Carl D. Brown. (2001) A Physiologically Based Pharmacokinetic Model for Ethylene Oxide in Mouse, Rat, and Human. Toxicology and Applied Pharmacology 173:3, pages 161-175.
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John M. Waechter, Lynn H. Pottenger & Gauke E. Veenstra. 2003. Patty's Toxicology. Patty's Toxicology.
Jan L. Vansteenhouse, Judith S. Prescott & Steven A. Barker. (2000) Identification of the 1-cyano-3,4-epithiobutane-derived urinary mercapturic acidn-acetyl-s-(4-cyano-2-thio-1-butyl)-cysteine in male fischer 344 rats. Journal of Applied Toxicology 20:1, pages 1-10.
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Lilian E. Thielemann, Cleofina Bosco, Ram�n Rodrigo, Myriam Orellana & Luis A. Videla. (1999) Effects of bromoethylamine on antioxidant capacity, lipid peroxidation, and morphological characteristics of rat liver. Journal of Biochemical and Molecular Toxicology 13:1, pages 47-52.
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Carl D. Brown, Bahman Asgharian, Max J. Turner & Timothy R. Fennell. (1998) Ethylene Oxide Dosimetry in the Mouse. Toxicology and Applied Pharmacology 148:2, pages 215-221.
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Sumsullah Khan, Christian Sood & Peter J. O'Brien. (2009) The Involvement of Cytochrome P4502E1 in 2‐Bromoethanol‐Induced Hepatocyte Cytotoxicity. Pharmacology & Toxicology 78:4, pages 241-248.
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M. Seakins, W. J. Griffiths, F. M. Harris, S. R. Andrews & D. E. Parry. (1993) Measured and calculated double-ionization energies of 2-haloethanols. Organic Mass Spectrometry 28:10, pages 1144-1147.
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G. J. A. Speijers. 1993. Chemistry and Analysis of Volatile Organic Compounds in the Environment. Chemistry and Analysis of Volatile Organic Compounds in the Environment 25 91 .
Mayo Uziel, Nancy B. Munro, D. Sue Katz, Tuan Vo-Dinh, Elaine A. Zeighami, Michael D. Waters & Jack D. Griffith. (1992) DNA adduct formation by 12 chemicals with populations potentially suitable for molecular epidemiological studies. Mutation Research/Reviews in Genetic Toxicology 277:1, pages 35-90.
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Kannan Krishnan, Michael L. Gargas, Timothy R. Fennell & Melvin E. Andersen. (1992) A Physiologically Based Description of Ethylene Oxide Dosimetry in the Rat. Toxicology and Industrial Health 8:3, pages 121-140.
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Chi-Chu Lo, Ming-Der Hung & Cheng-Jiung Liu. (1992) Replacement of carcinogenic alkylating agent ethylene oxide in the synthesis of (Z)-3-dodecen-1-YL (E)-2-butenoate, sex pheromone of sweet-potato weevil,Cylas formicarius elegantulus (summers) andCylas formicarius formicarius (F.). Journal of Chemical Ecology 18:2, pages 95-103.
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Hari K. Bhat, Gregory K. Asimakis & G.A.S. Ansari. (1991) Uncoupling of oxidative phosphorylation in rat liver mitochondria by chloroethanols. Toxicology Letters 59:1-3, pages 203-211.
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Robert Nilsson, Bruce Molholt & Edward V. Sargent. (1991) Quantitative assessment of a human carcinogenic potency for propylene oxide. Regulatory Toxicology and Pharmacology 14:3, pages 229-244.
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Takahiko Katoh, Hisamitsu Ohmori, Tadamasa Murakami, Yuji Karasaki, Ken Higashi & Masami Muramatsu. (1991) Induction of glutathione-S-transferase and heat-shock proteins in rat liver after ethylene oxide exposure. Biochemical Pharmacology 42:6, pages 1247-1254.
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Vernon E. Walker, Timothy R. Fennell, Joyce A. Boucheron, Norbert Fedtke, Françoise Ciroussel & James A. Swenberg. (1990) Macromolecular adducts of ethylene oxide: a literature review and a time-course study on the formation of 7-(2-hydroxyethyl) guanine following exposures of rats by inhalation. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 233:1-2, pages 151-164.
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Bhupendra S. Kaphalia & G. A. S. Ansari. (2006) Hepatic fatty acid conjugation of 2‐chloroethanol and 2‐bromoethanol in rats. Journal of Biochemical Toxicology 4:3, pages 183-188.
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N. P. E. Vermeulen, J. de Jong, E. J. C. van Bergen & R. T. H. van Welie. (1989) N-acetyl-S-(2-hydroxyethyl)-L-cysteine as a potential tool in biological monitoring studies?. Archives of Toxicology 63:3, pages 173-184.
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T. Shivanandappa & S. Rajendran. (1987) Induction of glutathione S-transterase by fumigants in larvae of the Khapra beetle, Trogoderma granarium (E.). Pesticide Biochemistry and Physiology 28:1, pages 121-126.
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Brian R. Pettit. (1986) The analysis of thiodiglycollic acid by selected ion monitoring. Clinica Chimica Acta 156:1, pages 85-90.
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J. G. Filser & H. M. Bolt. (1984) Inhalation pharmacokinetics based on gas uptake studies. Archives of Toxicology 55:4, pages 219-223.
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Gerhard Stucki & Thomas Leisinger. (1983) Bacterial degradation of 2-chloroethanol proceeds via 2-chloroacetic acid. FEMS Microbiology Letters 16:1, pages 123-126.
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