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Xenobiotica
the fate of foreign compounds in biological systems
Volume 12, 1982 - Issue 8
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Research Article

Differential effects of 3-methylcholanthrene and phenobarbitone treatment on the oxidative metabolism of antipyrine in vitro by microsomal fractions of rat liver

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Pages 509-516 | Received 10 Mar 1982, Published online: 22 Sep 2008

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Marwa E. Elsherbiny & Dion R. Brocks. (2011) The ability of polycyclic aromatic hydrocarbons to alter physiological factors underlying drug disposition. Drug Metabolism Reviews 43:4, pages 457-475.
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C. Palette, F. Dubor, V. Rovei & C. Advenier. (1993) Determination of antipyrine sulphoconjugates in isolated cultured rat hepatocytes. Xenobiotica 23:2, pages 181-191.
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S. Loft, A. J. Nielsen, B. E. Borg & H. E. Poulsen. (1991) Metronidazole and antipyrine metabolism in the rat: Clearance determination from one saliva sample. Xenobiotica 21:1, pages 33-46.
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S. Loft & H. E. Poulsen. (1990) Metabolism of metronidazole and antipyrine in hepatocytes isolated from mouse and rat. Xenobiotica 20:2, pages 185-191.
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M. Van Der Graaff, N. P. E. Vermeulen, P. Heij, H. De Bree & D. D. Breimer. (1986) Correlation between the metabolism of hexobarbital and aminopyrine in vivo in rats. Xenobiotica 16:12, pages 1091-1096.
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J. C. Rhodes, S. T. Hall & J. B. Houston. (1984) Inhibition of antipyrine metabolite formation in rats in vivo. Xenobiotica 14:9, pages 677-686.
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A. R. Boobis & D. S. Davies. (1984) Human cytochromes P-450. Xenobiotica 14:1-2, pages 151-185.
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M. W. E. Teunissen, M. Van Graft, N. P. E. Vermeulen & D. D. Breimer. (1983) Influence of allylisopropylacetamide and phenobarbital treatment on in vivo antipyrine metabolite formation in rats. Xenobiotica 13:8, pages 497-502.
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Articles from other publishers (16)

Mary‐Ann Efthivoulou & Michael N. Berry. (2006) Antipyrine and Aminopyrine Induce Acetaldehyde Accumulation from Ethanol in Isolated Hepatocytes. Alcoholism: Clinical and Experimental Research 21:2, pages 267-274.
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J.T.M. Buters, T. Zysset & J. Reichen. (1993) Metabolism of antipyrine in vivo in two rat models of liver cirrhosis ita relationship to intrinsic clearance in vitro and microsomal membrane lipid composition. Biochemical Pharmacology 46:6, pages 983-991.
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YH Park, JE Hudson, RC Barker, BM York & RK Brazzell. (2012) Metabolism of the aldose reductase inhibitor ALO1567 in man.. British Journal of Clinical Pharmacology 32:2, pages 221-227.
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Antero Aitio, Mirja‐Liisa Aitio, Anne‐Marie Camus, Elisabeth Cardis & Helmut Bartsch. (2005) Cytochrome P‐450 Isozyme Pattern Is Related to Individual Susceptibility to Diethylnitrosamine‐induced Liver Cancer in Rats. Japanese Journal of Cancer Research 82:2, pages 146-156.
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J.T.M. Buters & J. Reichen. (1990) Sex difference in antipyrine 3-hydroxylation. Biochemical Pharmacology 40:4, pages 771-777.
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Steffen Loft. (1990) Metronidazole and Antipyrine as Probes for the Study of Foreign Compound Metabolism. Pharmacology & Toxicology 66, pages 1-31.
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C.A.J.F. Van Geel & C.F.A. Van Bezooijen. (1990) The effect of age on the oxidative metabolism of antipyrine by uninduced microsomal fractions of rat liver. Mechanisms of Ageing and Development 53:2, pages 169-177.
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D.J. Henderson & C.F.A. van Bezooijen. (1989) The effect of age on antipyrine metabolism by liver microsomes isolated from phenobarbital-treated rats. Mechanisms of Ageing and Development 49:3, pages 287-294.
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Steffen Loft & Henrik Enohusen Poulsen. (1989) Metabolism of metronidazole and antipyrine in isolated rat hepatocytes. Biochemical Pharmacology 38:7, pages 1125-1136.
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Leslie B. Slusher, Sang S. Park, Harry V. Gelboin & Elliot S. Vesell. (1987) Studies on the metabolism of aminopyrine, antipyrine and theophylline using monoclonal antibodies to cytochrome P-450 isozymes purified from rat liver. Biochemical Pharmacology 36:14, pages 2359-2367.
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Hervé Dupont, Donald S. Davies & Margherita Strolin-Benedetti. (1987) Inhibition of cytochrome P-450-dependent oxidation reactions by mao inhibitors in rat liver microsomes. Biochemical Pharmacology 36:10, pages 1651-1657.
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Porntip Buppodom, Nobuyuki Koga, Hideyuki Yamada & Hidetoshi Yoshimura. (1986) Studies on rat liver cytochrome P-450s involved in the metabolism of antipyrine: phenobarbital- and 3-methylcholanthrene-inducible isozymes possessing 4-hydroxylase activity. Biochemical Pharmacology 35:8, pages 1404-1406.
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J. Moncrieff. (1986) Simultaneous assay of antipyrine and its major metabolites in urine using high-performance liquid chromatography and on-line solid phase sample clean-up. Journal of Chromatography B: Biomedical Sciences and Applications 383, pages 425-431.
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Gerd Kaupp, Fatih Köleli & Eleonore Gründken. (1985) Electrochemical Methoxylation of Antipyrine. Angewandte Chemie International Edition in English 24:10, pages 864-865.
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Gerd Kaupp, Fatih Köleli & Eleonore Gründken. (1985) Elektrochemische Methoxylierung von Antipyrin. Angewandte Chemie 97:10, pages 873-874.
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M.W.E. Teunissen, J.E.Meerburg-van der Torren, N.P.E. Vermeulen & D.D. Breimer. (1983) Automated high-performance liquid chromatographic determination of antipyrine and its main metabolites in plasma, saliva and urine, including 4,4′-dihydroxy-antipyrine. Journal of Chromatography B: Biomedical Sciences and Applications 278, pages 367-378.
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