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Xenobiotica
the fate of foreign compounds in biological systems
Volume 12, 1982 - Issue 9
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Research Article

The metabolism of benzyl isothiocyanate and its cysteine conjugate in guinea-pigs and rabbits

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Pages 535-542 | Received 10 Dec 1981, Published online: 22 Sep 2008

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Read on this site (5)

Evelyn Lamy, Cathy Scholtes, Corinna Herz & Volker Mersch-Sundermann. (2011) Pharmacokinetics and pharmacodynamics of isothiocyanates. Drug Metabolism Reviews 43:3, pages 387-407.
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Franca Bianchini & Harri Vainio. (2004) Isothiocyanates in Cancer Prevention. Drug Metabolism Reviews 36:3-4, pages 655-667.
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Hiroki Tomisawa, Noriko Ichimoto, Yohko Takanohashi, Shigeyasu Ichihara, Hideo Fukazawa & Mitsuru Tateishi. (1988) Purification and Characterization of Cysteine Conjugate Transaminases from Rat Liver. Xenobiotica 18:9, pages 1015-1028.
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W. H. Mennicke, K. GÖrler, G. Krumbiegel, D. Lorenz & N. Rittmann. (1988) Studies on the metabolism and excretion of benzyl isothiocyanate in man. Xenobiotica 18:4, pages 441-447.
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B. E. Hall & S. P. James. (1986) Mercapturic acid formation in the marmoset (Callithrix jacchus). Xenobiotica 16:7, pages 609-614.
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Articles from other publishers (20)

Alma MartelliValentina CitiLara TestaiSimone BrogiVincenzo Calderone. (2020) Organic Isothiocyanates as Hydrogen Sulfide Donors. Antioxidants & Redox Signaling 32:2, pages 110-144.
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M. Soledade C. Pedras & Chintamani Thapa. (2020) Unveiling fungal detoxification pathways of the cruciferous phytoalexin rapalexin A: Sequential L-cysteine conjugation, acetylation and oxidative cyclization mediated by Colletotrichum spp.. Phytochemistry 169, pages 112188.
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Franziska Beran, Theresa Sporer, Christian Paetz, Seung-Joon Ahn, Franziska Betzin, Grit Kunert, Anton Shekhov, Daniel G. Vassão, Stefan Bartram, Sybille Lorenz & Michael Reichelt. (2018) One Pathway Is Not Enough: The Cabbage Stem Flea Beetle Psylliodes chrysocephala Uses Multiple Strategies to Overcome the Glucosinolate-Myrosinase Defense in Its Host Plants. Frontiers in Plant Science 9.
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Julia Budnowski, Laura Hanske, Fabian Schumacher, Hansruedi Glatt, Stefanie Platz, Sascha Rohn & Michael Blaut. (2015) Glucosinolates Are Mainly Absorbed Intact in Germfree and Human Microbiota-Associated Mice. Journal of Agricultural and Food Chemistry 63:38, pages 8418-8428.
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Ah-Ng KongAnuradha Sehrawat & Shivendra Singh. 2013. Inflammation, Oxidative Stress, and Cancer. Inflammation, Oxidative Stress, and Cancer 447 462 .
Y. Zhang. (2011) The molecular basis that unifies the metabolism, cellular uptake and chemopreventive activities of dietary isothiocyanates. Carcinogenesis 33:1, pages 2-9.
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Ruud Verkerk, Monika Schreiner, Angelika Krumbein, Ewa Ciska, Birgit Holst, Ian Rowland, Remi De Schrijver, Magnor Hansen, Clarissa Gerhäuser, Richard Mithen & Matthijs Dekker. (2009) Glucosinolates in Brassica vegetables: The influence of the food supply chain on intake, bioavailability and human health. Molecular Nutrition & Food Research 53:S2, pages S219-S219.
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Akhilesh Kumar, Saritha S. D'Souza, Sanjay Tickoo, Bharathi P. SalimathH.B. Singh. (2009) Antiangiogenic and Proapoptotic Activities of Allyl Isothiocyanate Inhibit Ascites Tumor Growth in Vivo. Integrative Cancer Therapies 8:1, pages 75-87.
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. (2008) Glucosinolates as undesirable substances in animal feed - Scientific Opinion of the Panel on Contaminants in the Food Chain. EFSA Journal 6:1, pages 590.
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Martijn Vermeulen, Robin van den Berg, Andreas P. Freidig, Peter J. van Bladeren & Wouter H. J. Vaes. (2006) Association between Consumption of Cruciferous Vegetables and Condiments and Excretion in Urine of Isothiocyanate Mercapturic Acids. Journal of Agricultural and Food Chemistry 54:15, pages 5350-5358.
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Yan Ji, Yuhsin Kuo & Marilyn E. Morris. (2005) Pharmacokinetics of Dietary Phenethyl Isothiocyanate in Rats. Pharmaceutical Research 22:10, pages 1658-1666.
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Stephen S. Hecht. 2004. Cancer Chemoprevention. Cancer Chemoprevention 21 35 .
Martijn Vermeulen, Binne Zwanenburg, Gordon J.F Chittenden & Hans Verhagen. (2003) Synthesis of isothiocyanate-derived mercapturic acids. European Journal of Medicinal Chemistry 38:7-8, pages 729-737.
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Martijn Vermeulen, Hans J. M. van Rooijen & Wouter H. J. Vaes. (2003) Analysis of Isothiocyanate Mercapturic Acids in Urine:  A Biomarker for Cruciferous Vegetable Intake. Journal of Agricultural and Food Chemistry 51:12, pages 3554-3559.
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Yasushi Uda, Yoshio Ozawa & Koichi Yoneyama. 2002. Bioactive Natural Products. Bioactive Natural Products 1073 1111 .
H.‐J. Lewerenz, D. W. R. Bleyl & R. Plass. (2006) Subacute oral toxicity study of benzyl isothiocyanate in rats. Food / Nahrung 36:2, pages 190-198.
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J. Elks & C. R. Ganellin. 1990. Dictionary of Drugs. Dictionary of Drugs 119 203 .
Michel Vermorel, Robert K. Heaney & G. Roger Fenwick. (2006) Nutritive value of rapeseed meal: Effects of individual glucosinolates. Journal of the Science of Food and Agriculture 37:12, pages 1197-1202.
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Hiroki Tomisawa, Hideo Fukazawa, Shigeyasu Ichihara & Mitsuru Tateishi. (1986) A novel pathway for formation of thiol-containing metabolites from cysteine conjugates. Biochemical Pharmacology 35:13, pages 2270-2272.
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Walter Dorsch, Olaf Adam, Jörg Weber & Thomas Ziegeltrum. (1984) Antiasthmatic effects of onion extracts - detection of benzyl- and other isothiocyanates (mustard oils) as antiasthmatic compounds of plant origin. European Journal of Pharmacology 107:1, pages 17-24.
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