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Xenobiotica
the fate of foreign compounds in biological systems
Volume 12, 1982 - Issue 9
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Research Article

Studies on the metabolism of dimethylnitrosamine in vitro by rat-liver preparations.: II. Inhibition by substrates and inhibitors of monoamine oxidase

B. G. Lake The British Industrial Biological Research Association, Woodmansterne Road, Carshalton, Surrey, SM5 4DS, UK
,
Rosalyn A. Harris The British Industrial Biological Research Association, Woodmansterne Road, Carshalton, Surrey, SM5 4DS, UK
,
M. A. Collins The British Industrial Biological Research Association, Woodmansterne Road, Carshalton, Surrey, SM5 4DS, UK
,
R. C. Cottrell The British Industrial Biological Research Association, Woodmansterne Road, Carshalton, Surrey, SM5 4DS, UK
,
J. C. Phillips The British Industrial Biological Research Association, Woodmansterne Road, Carshalton, Surrey, SM5 4DS, UK
&
S. D. Gangolli The British Industrial Biological Research Association, Woodmansterne Road, Carshalton, Surrey, SM5 4DS, UK
Pages 567-579 | Received 22 Mar 1982, Published online: 22 Sep 2008

Citations (14)

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Bin Gong & Paul J Boor. (2006) The role of amine oxidases in xenobiotic metabolism. Expert Opinion on Drug Metabolism & Toxicology 2:4, pages 559-571.
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B. G. Lake, M. A. Collins, Rosalyn A. Harris, J. C. Phillips, R. C. Cottrell, R. C. Longland & S. D. Gangolli. (1982) Studies on the metabolism of dimethylnitrosamine in vitro by rat-liver preparations.: III. Effect of cobaltous chloride treatment. Xenobiotica 12:9, pages 581-590.
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Articles from other publishers (12)

Brian G. Lake, Roger J. Price, David G. Walters, John C. Phillips, Philip J. Young & Timothy B. Adams. (2003) Studies on the metabolism of the thiofurans furfuryl mercaptan and 2-methyl-3-furanthiol in rat liver. Food and Chemical Toxicology 41:12, pages 1761-1770.
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Tomáš Gichner & Jiří Velemínský. (1988) Mechanisms of inhibition of N-nitroso compounds-induced mutagenicity. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 202:2, pages 325-334.
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Kim Dong-Hyun, Yang Kyu-Hwan, Kirk W. Johnson & Michael P. Holsapple. (1988) Role of the transfer of metabolites from hepatocytes to splenocytes in the suppression of in vitro antibody response by dimethylnitrosamine. Biochemical Pharmacology 37:14, pages 2765-2771.
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Tomáš Gichner & Jiří Velemínský. (1988) Inhibitors of N-nitroso compounds-induced mutagenicity. Mutation Research/Reviews in Genetic Toxicology 195:1, pages 21-43.
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Joseph B. Guttenplan. (1987) N-nitrosamines: bacterial mutagenesis and in vitro metabolism. Mutation Research/Reviews in Genetic Toxicology 186:2, pages 81-134.
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Howard S. Ramsdell & Donald R. Buhler. (1987) Microsomal metabolism of pyrrolizidine alkaloids: N-oxidation of seneciphylline and senecionine. Toxicology Letters 37:3, pages 241-249.
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A.J. Alldrick, B.G. Lake, J. Flynn & I.R. Rowland. (1986) Metabolic conversion of IQ and MeIQ to bacterial mutagens. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 163:2, pages 109-114.
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Toru Kawanishi, Yasuo Ohno, Atsushi Takahashi, Akira Takanara, Yutaka Kasuya & Yoshihito Omori. (1985) Relation between hepatic microsomal metabolism of N-nitrosamines and cytochrome P-450 species. Biochemical Pharmacology 34:7, pages 919-924.
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Karen Lynn Kaul & Raymond F. Novak. (1984) Induction of rabbit hepatic microsomal cytochrome P-450 by imidazole: Enhanced metabolic activity and altered substrate specificity. Archives of Biochemistry and Biophysics 235:2, pages 470-481.
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T. Kawanishi, Y. Ohno, A. Takahashi, A. Takanaka, Y. Kasuya & Y. Omori. (1984) Nature of N-nitrosodimethylamine demethylase. Archives of Toxicology 56:1, pages 7-11.
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Beverly A. Smith & Helmut R. Gutmann. (1984) Differential effect of chronic ethanol consumption by the rat on microsomal oxidation of hepatocarcinogens and their activation to mutagens. Biochemical Pharmacology 33:18, pages 2901-2910.
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P. Schmezer, R.G. Klein & B. Spiegelhalder. (1984) Urinary excretion of N-nitrosodimethylamine in rats after Thalamonal narcosis. Cancer Letters 23:3, pages 351-353.
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