Riina Harjumäki, Chris S. Pridgeon & Magnus Ingelman-Sundberg. (2021) CYP2E1 in Alcoholic and Non-Alcoholic Liver Injury. Roles of ROS, Reactive Intermediates and Lipid Overload. International Journal of Molecular Sciences 22:15, pages 8221.
Crossref
Rolf Teschke. (2018) Alcoholic Liver Disease: Alcohol Metabolism, Cascade of Molecular Mechanisms, Cellular Targets, and Clinical Aspects. Biomedicines 6:4, pages 106.
Crossref
Qi Sun, Gaoyang Wang, Lanyue Gao, Lei Shi, Ying Qi, Xiuqiang Lv & Yaping Jin. (2016) Roles of CYP2e1 in 1,2-dichloroethane-induced liver damage in mice. Environmental Toxicology 31:11, pages 1430-1438.
Crossref
Stephen Nesnow. 2016. Toxicogenomics in Predictive Carcinogenicity. Toxicogenomics in Predictive Carcinogenicity
280
351
.
Eugene G. Hrycay & Stelvio M. Bandiera. 2015. Cytochrome P450 Function and Pharmacological Roles in Inflammation and Cancer. Cytochrome P450 Function and Pharmacological Roles in Inflammation and Cancer
35
84
.
Stephen Nesnow. (2013) Integration of toxicological approaches with “omic” and related technologies to elucidate mechanisms of carcinogenic action: Propiconazole, an example. Cancer Letters 334:1, pages 20-27.
Crossref
Barbara Tomasello, Chiara Copat, Valentina Pulvirenti, Venera Ferrito, Margherita Ferrante, Marcella Renis, Salvatore Sciacca & Concetta Tigano. (2012) Biochemical and bioaccumulation approaches for investigating marine pollution using Mediterranean rainbow wrasse, Coris julis (Linneaus 1798). Ecotoxicology and Environmental Safety 86, pages 168-175.
Crossref
Eugene G. Hrycay & Stelvio M. Bandiera. (2012) The monooxygenase, peroxidase, and peroxygenase properties of cytochrome P450. Archives of Biochemistry and Biophysics 522:2, pages 71-89.
Crossref
Stephen Nesnow, Rachel D. Grindstaff, Guy Lambert, William T. Padgett, Maribel Bruno, Yue Ge, Pei-Jen Chen, Charles E. Wood & Lynea Murphy. (2011) Propiconazole increases reactive oxygen species levels in mouse hepatic cells in culture and in mouse liver by a cytochrome P450 enzyme mediated process. Chemico-Biological Interactions 194:1, pages 79-89.
Crossref
C A Joseph & P A F Dixon. (1984)
A possible cytochrome P-450-mediated
N
-oxidation of diethylcarbamazine
. Journal of Pharmacy and Pharmacology 36:10, pages 711-712.
Crossref
Dimosthenis L. Giokas, Amparo Salvador & Alberto Chisvert. (2007) UV filters: From sunscreens to human body and the environment. TrAC Trends in Analytical Chemistry 26:5, pages 360-374.
Crossref
Evgeny Denisov & Igor Afanas’ev. 2005. Oxidation and Antioxidants in Organic Chemistry and Biology. Oxidation and Antioxidants in Organic Chemistry and Biology
1
284
.
Giada Frenzilli, Vittoria Scarcelli, Ilaria Del Barga, Marco Nigro, Lars Förlin, Claudia Bolognesi & Joachim Sturve. (2004) DNA damage in eelpout (Zoarces viviparus) from Göteborg harbour. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 552:1-2, pages 187-195.
Crossref
Diane J Lees Murdock, Yvonne A Barnett & Christopher R Barnett. (2004) DNA damage and cytotoxicity in pancreatic ?-cells expressing human CYP2E1. Biochemical Pharmacology 68:3, pages 523-530.
Crossref
Qing-Xue Zhang, Zoya Melnikov & Dennis E. Feierman. (2004) Characterization of the Acetaminophen-Induced Degradation of Cytochrome P450-3A4 and the Proteolytic Pathway. Pharmacology and Toxicology 94:4, pages 191-200.
Crossref
Jürgen Fuchs & Lester PackerJames Klaunig & Lisa Kamendulis. 2001. Environmental Stressors in Health and Disease. Environmental Stressors in Health and Disease.
Moreno Paolini, Giuseppa Potenza, GianLuigi Biagi & Giorgio Cantelli-Forti. (2001) Re: Ethylbenzene Induces Microsomal Oxygen Free Radical Generation: Antibody-Directed Characterization of the Responsible Cytochrome P450 Enzymes (Toxicol. Appl. Pharmacol.164, 305–311, 2000). Toxicology and Applied Pharmacology 173:3, pages 188.
Crossref
J E Klaunig, L M Kamendulis & Yong Xu. (2016) Epigenetic mechanisms of chemical carcinogenesis. Human & Experimental Toxicology 19:10, pages 543-555.
Crossref
Sonia C. Serron, Neelam Dwivedi & Wayne L. Backes. (2000) Ethylbenzene Induces Microsomal Oxygen Free Radical Generation: Antibody-Directed Characterization of the Responsible Cytochrome P450 Enzymes. Toxicology and Applied Pharmacology 164:3, pages 305-311.
Crossref
I. E. Kovalev & E. I. Rumyantseva. (1999) Diabetes (ethanol) induced isoform of cytochrome P-450. A new theoretical bases in the search for pharmacological methods of correction of some pathological processes involved in diabetes mellitus. Pharmaceutical Chemistry Journal 33:6.
Crossref
Hiroshi Tsukada, Pei-Yu Wang, Takashi Kaneko, Yuan Wang, Masayuki Nakano & Akio Sato. (1998) Dietary carbohydrate intake plays an important role in preventing alcoholic fatty liver in the rat. Journal of Hepatology 29:5, pages 715-724.
Crossref
D.F.V Lewis, C Ioannides & D.V Parke. (1998) Further evaluation of COMPACT, the molecular orbital approach for the prospective safety evaluation of chemicals. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 412:1, pages 41-54.
Crossref
Teresa Wrońska-Nofer, Justyna Wiśniewska-Knypl, Kalina Wyszyńska & Elżbieta Dziubałtowska. (1997) Genotoxicity of industrial dyes under the inductive effect of ethanol on monooxygenase system in mice. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 392:3, pages 229-235.
Crossref
Shigeyuki Sugie, Kiyohisa Okamoto, Masami Ohnishi, Hiroki Makita, Toshihiko Kawamori, Tomoyuki Watanabe, Takuji Tanaka, Yasushi K. Nakamura, Yoshiyuki Nakamura, Isao Tomita & Hideki Mori. (2005) Suppressive Effects of S‐Methyl Methanethiosulfonate on Promotion Stage of Diethylnitrosamine‐initiated and Phenobarbital‐promoted Hepatocarcinogenesis Model. Japanese Journal of Cancer Research 88:1, pages 5-11.
Crossref
Laurie D. DeLeve & Neil Kaplowitz. (1995) MECHANISMS OF DRUG-INDUCED LIVER DISEASE. Gastroenterology Clinics of North America 24:4, pages 787-810.
Crossref
E. Albano, A. Comoglio, P. Clot, A. Iannone, A. Tomasi & M. Ingelman-Sundberg. (1995) Activation of alkylhydrazines to free radical intermediates by ethanol-inducible cytochrome P-4502E1 (CYP2E1). Biochimica et Biophysica Acta (BBA) - General Subjects 1243:3, pages 414-420.
Crossref
Chukwuemeka S. Okereke, Mohamed S. Abdel-Rhaman & Marvin A. Friedman. (1994) Disposition of benzophenone-3 after dermal administration in male rats. Toxicology Letters 73:2, pages 113-122.
Crossref
P. Souček, B. Filipcova & I. Gut. (1994) Cytochrome P450 destruction and radical scavenging by benzene and its metabolites. Biochemical Pharmacology 47:12, pages 2233-2242.
Crossref
Magnus Ingelman-Sundberg, Inger Johansson, Hu Yin, Ylva Terelius, Erik Eliasson, Paolo Clot & Emanuele Albano. (1993) Ethanol-inducible cytochrome P4502E1: Genetic polymorphism, regulation, and possible role in the etiology of alcohol-induced liver disease. Alcohol 10:6, pages 447-452.
Crossref
Peter Hlavica & Ute Künzel-Mulas. (1993) Metabolic N-oxide formation by rabbit-liver microsomal cytochrome P-4502B4: involvement of superoxide in the NADPH-dependent N-oxygenation of N,N-dimethylaniline. Biochimica et Biophysica Acta (BBA) - General Subjects 1158:1, pages 83-90.
Crossref
Richard T. Di Giulio, Clifford Habig & Evan P. Gallagher. (1993) Effects of Black Rock Harbor sediments on indices of biotransformation, oxidative stress, and DNA integrity in channel catfish. Aquatic Toxicology 26:1-2, pages 1-22.
Crossref
David F.V. Lewis, C. Ioannides & D.V. Parke. (1993) Validation of a novel molecular orbital approach (COMPACT) for the prospective safety evaluation of chemicals, by comparison with rodent carcinogenicity and Salmonella mutagenicity data evaluated by the U.S. NCI/NTP. Mutation Research/Environmental Mutagenesis and Related Subjects 291:1, pages 61-77.
Crossref
DAVID R. NELSON, TETSUYA KAMATAKI, DAVID J. WAXMAN, F. PETER GUENGERICH, RONALD W. ESTABROOK, RENE FEYEREISEN, FRANK J. GONZALEZ, MINOR J. COON, IRWIN C. GUNSALUS, OSAMU GOTOH, KYUICHIRO OKUDA & DANIEL W. NEBERT. (1993) The P450 Superfamily: Update on New Sequences, Gene Mapping, Accession Numbers, Early Trivial Names of Enzymes, and Nomenclature. DNA and Cell Biology 12:1, pages 1-51.
Crossref
F. Peter Guengerich & Timothy L. Macdonald. 1993. Advances in Electron Transfer Chemistry. Advances in Electron Transfer Chemistry
191
241
.
Magnus Ingelman-Sundberg. 1993. Free Radicals: from Basic Science to Medicine. Free Radicals: from Basic Science to Medicine
287
301
.
Hisao Takahashi, Inger Johansson, Samuel W. French & Magnus Ingelman‐Sundberg. (2009) Effects of Dietary Fat Composition on Activities of the Microsomal Ethanol Oxidizing System and Ethanol‐Inducible Cytochrome P450 (CYP2E1) in the Liver of Rats Chronically Fed Ethanol. Pharmacology & Toxicology 70:5, pages 347-351.
Crossref
Roger Nordmann, Catherine Ribière & Hélène Rouach. (1992) Implication of free radical mechanisms in ethanol-induced cellular injury. Free Radical Biology and Medicine 12:3, pages 219-240.
Crossref
Susumu Imaoka & Yoshihiko Funae. (1991) Induction of cytochrome P450 isozymes in rat liver by methyl n-alkyl ketones and n-alkylbenzenes. Biochemical Pharmacology 42, pages S143-S150.
Crossref
Keith A. Baarson & Carroll A. Snyder. (1991) Evidence for the disruption of the bone marrow microenvironment by combined exposures to inhaled benzene and ingested ethanol. Archives of Toxicology 65:5, pages 414-420.
Crossref
Martin J. J. RONIS, Inger JOHANSSON, Kjell HULTENBY, Jacob LAGERCRANTZ, Hans GLAUMANN & Magnus INGELMAN‐SUNDBERG. (2005)
Acetone‐regulated synthesis and degradation of cytochrome
P
4502
E
2 and cytochrome
P
4502
B
1 in rat liver
. European Journal of Biochemistry 198:2, pages 383-389.
Crossref
Emanuele Albano, Aldo Tomasi, Jan-Olov Persson, Ylva Terelius, Lucia Goria-Gatti, Magnus Ingelman-Sundberg & Mario U. Dianzani. (1991) Role of ethanol-inducible cytochrome P450 (P450IIE1) in catalysing the free radical activation of aliphatic alcohols. Biochemical Pharmacology 41:12, pages 1895-1902.
Crossref
Dieter Pankow, Frank Matschiner & Hans-Jürgen Weigmann. (1991) Influence of aromatic hydrocarbons on the metabolism of dichloromethane to carbon monoxide in rats. Toxicology 68:1, pages 89-100.
Crossref
J. E. A. Leakey, J. J. Bazare, J. R. Harmon, R. J. Feuers, P. H. Duffy & R. W. Hart. 1991. Biological Effects of Dietary Restriction. Biological Effects of Dietary Restriction
207
216
.
Eric F. Johnson, Thomas Kronbach, A. Scott Muerhoff, Keith J. Griffin, Usha R. Pendurthi & Robert H. Tukey. 1991. Molecular Aspects of Monooxygenases and Bioactivation of Toxic Compounds. Molecular Aspects of Monooxygenases and Bioactivation of Toxic Compounds
23
54
.
D.F.V. Lewis, C. Ioannides & D.V. Parke. (1990) A retrospective study of the molecular toxicology of benoxaprofen. Toxicology 65:1-2, pages 33-47.
Crossref
Dennis V. Parke, Costas Ioannides & David F.V. Lewis. (2020) The Safety Evaluation of Drugs and Chemicals by the Use of Computer Optimised Molecular Parametric Analysis of Chemical Toxicity (COMPACT). Alternatives to Laboratory Animals 18:1_part_1, pages 91-102.
Crossref
William W. Au, Wagida A. Anwar, Elie Hanania & V. M. Sadagopa Ramanujam. 1990. Antimutagenesis and Anticarcinogenesis Mechanisms II. Antimutagenesis and Anticarcinogenesis Mechanisms II
389
393
.
C Norsten, T Cronholm, G Ekström, J A Handler, R G Thurman & M Ingelman-Sundberg. (1989) Dehydrogenase-dependent Ethanol Metabolism in Deer Mice (Peromyscus maniculatus) Lacking Cytosolic Alcohol Dehydrogenase. Journal of Biological Chemistry 264:10, pages 5593-5597.
Crossref
Dennis R. Koop, Carmen L. Laethem & Gregory G. Schnier. (1989) Identification of ethanol-inducible P450 isozyme 3a (P450IIE1) as a benzene and phenol hydroxylase. Toxicology and Applied Pharmacology 98:2, pages 278-288.
Crossref
Gunilla Ekström, Christer von Bahr & Magnus Ingelman-Sundberg. (1989) Human liver microsomal cytochrome P-450IIE1. Imnunological evaluation of its contribution to microsomal ethanol oxidation, carboti tetrachloride reduction and NADPH oxidase activity. Biochemical Pharmacology 38:4, pages 689-693.
Crossref
Catherine S.E. Jewell & Gary W. Winston. (1989) Oxyradical production by hepatopancreas microsomes from the red swamp crayfish, Procambarus clarkii. Aquatic Toxicology 14:1, pages 27-46.
Crossref
Inger Johansson, Gunilla Ekstroem, Bob Scholte, David Puzycki, Hans Jörnvall & Magnus Ingelman-Sundberg. (2002) Ethanol-, fasting-, and aceton-inducible cytochromes P-450 in rat liver: regulation and characteristics of enzymes belonging to the IIB and IIE gene subfamilies. Biochemistry 27:6, pages 1925-1934.
Crossref
James J. Freeman & Eileen P. Hayes. (1988) Microsomal metabolism of acetonitrile to cyanide. Biochemical Pharmacology 37:6, pages 1153-1159.
Crossref
Erik Eliasson, Inger Johansson & Magnus Ingelman-Sundberg. (1988) Ligand-dependent maintenance of ethanol-inducible cytochrome P-450 in primary rat hepatocyte cell cultures. Biochemical and Biophysical Research Communications 150:1, pages 436-443.
Crossref
Joseph V. BoykinJrJr & Nancy H. Manson. (1987) Mechanisms of cimetidine protection following thermal injury. The American Journal of Medicine 83:6, pages 76-81.
Crossref
Barbara L. Harper & Marvin S. Legator. (1987) Pyridine prevents the clastogenicity of benzene but not of benzo[a]pyrene or cyclophosphamide. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 179:1, pages 23-31.
Crossref
J. E. Fleming, R. B. Shibuya & K. G. Bensch. (1987) Lifespan, oxygen consumption and hydroxyl radical scavenging capacity of two strains of Drosophila melanogaster. AGE 10:3, pages 86-89.
Crossref
David F.V. Lewis. (1987) Quantitative structure-activity relationships in a series of alcohols exhibiting inhibition of cytochrome P-450-mediated aniline hydroxylation. Chemico-Biological Interactions 62:3, pages 271-280.
Crossref
Dennis R. Koop & Minor J. Coon. (1986) Ethanol Oxidation and Toxicity: Role of Alcohol P-450 Oxygenase. Alcoholism: Clinical and Experimental Research 10:s1, pages 44S-49S.
Crossref
Rolf Teschke & Jurgen Gellert. (1986) Hepatic Microsomal Ethanol-Oxidizing System (MEOS): Metabolic Aspects and Clinical Implications. Alcoholism: Clinical and Experimental Research 10:s1, pages 20S-32S.
Crossref
Ylva TERELIUS & Magnus INGELMAN-SUNDBERG. (1986) Metabolism of n-pentane by ethanol-inducible cytochrome P-450 in liver microsomes and reconstituted membranes. European Journal of Biochemistry 161:2, pages 303-308.
Crossref
Randall J. Ruch & James E. Klaunig. (1986) Antioxidant prevention of tumor promoter induced inhibition of mouse hepatocyte intercellular communication. Cancer Letters 33:2, pages 137-150.
Crossref
Eileen P. Hayes, Peter Scala & Gisela Witz. (1986) Lipid composition of liver microsomes from rats treated with acetone. Toxicology Letters 31:2, pages 139-145.
Crossref
A. Bast & M. H. M. Steeghs. (1986) Hydroxyl radicals are not involved in NADPH dependent microsomal lipid peroxidation. Experientia 42:5, pages 555-556.
Crossref
Inger Johansson, Erik Eliasson, Carina Norsten & Magnus Ingelman-Sundberg. (1986) Hydroxylation of acetone by ethanol- and acetone-inducible cytochrome P-450 in liver microsomes and reconstituted membranes. FEBS Letters 196:1, pages 59-64.
Crossref
Costas Ioannides & Christine M. Steele. (1986) Hepatic microsomal mixed-function oxidase activity in ethanol-treated hamsters and its consequences on the bioactivation of aromatic amines to mutagens. Chemico-Biological Interactions 59, pages 129-139.
Crossref
Aalt Bast. (1986) Is formation of reactive oxygen by cytochrome P-450 perilous and predictable?. Trends in Pharmacological Sciences 7, pages 266-270.
Crossref
James C. Griffiths, George F. Kalf & Robert Snyder. 1986. Biological Reactive Intermediates III. Biological Reactive Intermediates III
213
222
.
Hiroshi Fujii, Tetsuo Ohmachi, Ikuko Sagami & Minro Watanabe. (1985) Liver microsomal drug metabolism in ethanol-treated hamsters. Biochemical Pharmacology 34:21, pages 3881-3884.
Crossref
Inger Johansson & Magnus Ingelman-Sundberg. (1985) Carbon tetrachloride-induced lipid peroxidation dependent on an ethanol-inducible form of rabbit liver microsomal cytochrome P-450. FEBS Letters 183:2, pages 265-269.
Crossref
Holger Luthman & Magnus Ingelman‐Sundberg. (2009) Cytochrome P‐450‐dependent Fragmentation of DNA in Reconstituted Membranes. Acta Pharmacologica et Toxicologica 56:1, pages 69-74.
Crossref
P.A.F. Dixon, S.E. Okereke & M.C.N. Enwelum. (1985) Influence of species, sex and drug pretreatment on the metabolism of metyrapone. Comparative Biochemistry and Physiology Part C: Comparative Pharmacology 81:1, pages 241-243.
Crossref
Magnus Ingelman-Sundberg & Hans J?rnvall. (1984) Induction of the ethanol-inducible form of rabbit liver microsomal cytochrome P-450 by inhibitors of alcohol dehydrogenase. Biochemical and Biophysical Research Communications 124:2, pages 375-382.
Crossref
Gunilla Ekstr?m & Magnus Ingelman-Sundberg. (1984) Cytochrome P-450-dependent lipid peroxidation in reconstituted membrane vesicles. Biochemical Pharmacology 33:15, pages 2521-2523.
Crossref
M Ingelman-Sundberg & I Johansson. (1984) Mechanisms of hydroxyl radical formation and ethanol oxidation by ethanol-inducible and other forms of rabbit liver microsomal cytochromes P-450.. Journal of Biological Chemistry 259:10, pages 6447-6458.
Crossref
Kevin E. Driscoll & Carroll A. Snyder. (1984) The effects of ethanol ingestion and repeated benzene exposures on benzene pharmacokinetics. Toxicology and Applied Pharmacology 73:3, pages 525-532.
Crossref
Gary J. Rosenthal & Carroll A. Snyder. (1984) The effects of ethanol and the role of the spleen during benzene-induced hematotoxicity. Toxicology 30:4, pages 283-295.
Crossref
Thomas Rushmore, Robert Snyder & George Kalf. (1984) Covalent binding of benzene and its metabolites to DNA in rabbit bone marrow mitochondria in vitro. Chemico-Biological Interactions 49:1-2, pages 135-154.
Crossref
D. V. Parke & C. Ioannides. 1984. Disease, Metabolism and Reproduction in the Toxic Response to Drugs and Other Chemicals. Disease, Metabolism and Reproduction in the Toxic Response to Drugs and Other Chemicals
183
192
.
Donald C. Borg & Karen M. Schaich. (1984) Cytotoxicity from Coupled Redox Cycling of Autoxidizing Xenobiotics and Metals: A Selective Critical Review and Commentary on Work-in-Progress. Israel Journal of Chemistry 24:1, pages 38-53.
Crossref
Thomas W. Kensler & Michael A. Trush. (2006) Role of oxygen radicals in tumor promotion. Environmental Mutagenesis 6:4, pages 593-616.
Crossref
Caroline E. Phillipson & Costas Ioannides. (1983) Activation of aromatic amines to mutagens by various animal species including man. Mutation Research/Genetic Toxicology 124:3-4, pages 325-336.
Crossref
I Johansson & M Ingelman-Sundberg. (1983) Hydroxyl radical-mediated, cytochrome P-450-dependent metabolic activation of benzene in microsomes and reconstituted enzyme systems from rabbit liver.. Journal of Biological Chemistry 258:12, pages 7311-7316.
Crossref